Erika S O Patriota1, Isis C C Lima1, Eduardo A F Nilson2, Sylvia C C Franceschini3, Vivian S S Gonçalves4, Nathalia Pizato5. 1. University of Brasilia, Graduate Program in Human Nutrition, Brasilia, Brazil. 2. University of Sao Paulo, Center for Epidemiological Research in Nutrition and Public Health, Brasilia, Brazil. 3. Federal University of Viçosa, Graduate Program in Nutrition Sciences, Brasilia, Brazil. 4. University of Brasilia, Graduate Program in Public Health, Brasilia, Brazil. 5. University of Brasilia, Graduate Program in Human Nutrition, Brasilia, Brazil. pizatonat@unb.br.
Abstract
BACKGROUND/ OBJECTIVES: Iodine deficiency in pregnant women is related to impaired foetal growth and development. The objective of this study was to estimate the prevalence of insufficient iodine intake in pregnant women from different regions of the world. SUBJECTS/ METHODS: Using the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines, five electronic databases and Google Scholar grey literature were searched until 10 April 2021. Two reviewers independently conducted article selection, data extraction, and assessment of the risk of bias. Meta-analyses with random effects, subgroup analyses, and meta-regressions were performed. RESULTS: In total, 4639 observational articles were found, with 61 eligible for inclusion. The population consisted of 163,021 pregnant women adults and adolescents, and the overall prevalence of insufficient iodine intake was 53% (95% confidence interval [CI]: 47-60; I2 = 99.8%). Pregnant women who live in insufficient iodine status country had a higher prevalence (86%; 95% CI: 78-93; I² =97.0%) of inadequate iodine nutritional status than to those living in country considered sufficient (51%; 95% IC: 45-57; I² = 99.8%). CONCLUSION: Despite the progress in iodine fortification policies and periodic monitoring of the iodine nutritional status of the population worldwide, salt iodination alone may not be sufficient to provide adequate iodine status to pregnant women. Thus, other actions may be necessary to improve the nutritional clinical care of pregnant group.
BACKGROUND/ OBJECTIVES: Iodine deficiency in pregnant women is related to impaired foetal growth and development. The objective of this study was to estimate the prevalence of insufficient iodine intake in pregnant women from different regions of the world. SUBJECTS/ METHODS: Using the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines, five electronic databases and Google Scholar grey literature were searched until 10 April 2021. Two reviewers independently conducted article selection, data extraction, and assessment of the risk of bias. Meta-analyses with random effects, subgroup analyses, and meta-regressions were performed. RESULTS: In total, 4639 observational articles were found, with 61 eligible for inclusion. The population consisted of 163,021 pregnant women adults and adolescents, and the overall prevalence of insufficient iodine intake was 53% (95% confidence interval [CI]: 47-60; I2 = 99.8%). Pregnant women who live in insufficient iodine status country had a higher prevalence (86%; 95% CI: 78-93; I² =97.0%) of inadequate iodine nutritional status than to those living in country considered sufficient (51%; 95% IC: 45-57; I² = 99.8%). CONCLUSION: Despite the progress in iodine fortification policies and periodic monitoring of the iodine nutritional status of the population worldwide, salt iodination alone may not be sufficient to provide adequate iodine status to pregnant women. Thus, other actions may be necessary to improve the nutritional clinical care of pregnant group.
Authors: Aline C Candido; Núbia de S de Morais; Luiza V Dutra; Carina A Pinto; Sylvia do C C Franceschini; Rita de Cássia G Alfenas Journal: Arch Endocrinol Metab Date: 2019-07-18 Impact factor: 2.309
Authors: David Moher; Larissa Shamseer; Mike Clarke; Davina Ghersi; Alessandro Liberati; Mark Petticrew; Paul Shekelle; Lesley A Stewart Journal: Syst Rev Date: 2015-01-01
Authors: Dal Lae Ju; Sun Wook Cho; Chae Won Chung; Young Ah Lee; Gi Jeong Cheon; Young Joo Park; Choong Ho Shin; Jong Kwan Jun; June-Key Chung; Sue K Park; YoonJu Song Journal: Eur J Nutr Date: 2022-08-10 Impact factor: 4.865