Literature DB >> 27966219

Oncofertility program implementation increases access to fertility preservation options and assisted reproductive procedures for breast cancer patients.

Joceline V Vu1, Natalia C Llarena2, Samantha L Estevez2, Molly B Moravek3, Jacqueline S Jeruss1,4.   

Abstract

BACKGROUND AND OBJECTIVES: Breast cancer treatment can cause premature ovarian failure, yet the majority of young cancer patients do not receive adequate education about treatment effects before initiating chemotherapy. We studied the impact of an oncofertility program on access to fertility preservation.
METHODS: An oncofertility program was initiated to foster collaboration between oncologists and reproductive endocrinologists, and to help increase access to fertility preservation. Documented conversations about fertility concerns, specialist referrals, appointments, and fertility preservation procedures were compared between breast cancer patients from 2004 to 2006, before oncofertility program initiation, and 2007-2012, after program initiation. The study included women <45, stages 0-III, diagnosed before (n = 278) and after (n = 515) program initiation.
RESULTS: Demographics for the cohorts were similar. Fertility discussions (P < 0.0001), patients interested in maintaining fertility at diagnosis (P = 0.0041), referrals to reproductive endocrinologists (P < 0.0001), appointments (P < 0.0001), and fertility preservation procedures (P < 0.0183) increased significantly after programmatic implementation.
CONCLUSIONS: An oncofertility program increased discussions about fertility preservation and access to assisted reproductive procedures. This program positively impacted compliance with national guidelines advising reproductive-age cancer patients to be offered fertility preservation counseling as an initial component of the multidisciplinary care plan. J. Surg. Oncol. 2017;115:116-121.
© 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

Entities:  

Keywords:  breast cancer; fertility preservation; oncofertility; reproductive endocrinology

Mesh:

Year:  2016        PMID: 27966219      PMCID: PMC5292230          DOI: 10.1002/jso.24418

Source DB:  PubMed          Journal:  J Surg Oncol        ISSN: 0022-4790            Impact factor:   3.454


  35 in total

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Authors: 
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Journal:  J Urol       Date:  2012-01-20       Impact factor: 7.450

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Review 5.  Discussing fertility preservation with breast cancer patients.

Authors:  Jacqueline S Jeruss
Journal:  Cancer Treat Res       Date:  2010

Review 6.  Oncofertility: a grand collaboration between reproductive medicine and oncology.

Authors:  Teresa K Woodruff
Journal:  Reproduction       Date:  2015-06-30       Impact factor: 3.906

7.  Goserelin for ovarian protection during breast-cancer adjuvant chemotherapy.

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Authors:  Bruce S Shapiro; Said T Daneshmand; Forest C Garner; Martha Aguirre; Cynthia Hudson; Shyni Thomas
Journal:  Fertil Steril       Date:  2009-08-14       Impact factor: 7.329

Review 9.  Preservation of fertility in patients with cancer.

Authors:  Jacqueline S Jeruss; Teresa K Woodruff
Journal:  N Engl J Med       Date:  2009-02-26       Impact factor: 91.245

Review 10.  Toxicity of chemotherapy and radiation on female reproduction.

Authors:  Dror Meirow; Hannah Biederman; Richard A Anderson; W Hamish B Wallace
Journal:  Clin Obstet Gynecol       Date:  2010-12       Impact factor: 2.190

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3.  Fertility preservation in patients of childbearing age treated for breast cancer: A nationwide cohort study.

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5.  Specific protocols of controlled ovarian stimulation for oocyte cryopreservation in breast cancer patients.

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Journal:  Curr Oncol       Date:  2018-12-01       Impact factor: 3.677

6.  Patterns of Referral for Fertility Preservation Among Female Adolescents and Young Adults with Breast Cancer: A Population-Based Study.

Authors:  Ann Korkidakis; Katherine Lajkosz; Michael Green; Donna Strobino; Maria P Velez
Journal:  J Adolesc Young Adult Oncol       Date:  2019-01-24       Impact factor: 2.223

Review 7.  Gonadotropin-releasing hormone agonists during chemotherapy for ovarian function and fertility preservation for patients with early-stage breast cancer.

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8.  The National Physicians Cooperative: transforming fertility management in the cancer setting and beyond.

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Journal:  Future Oncol       Date:  2018-11-26       Impact factor: 3.404

9.  How can we improve oncofertility care for patients? A systematic scoping review of current international practice and models of care.

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Journal:  Hum Reprod Update       Date:  2019-03-01       Impact factor: 15.610

10.  Consult and procedure incidence outcomes following establishment of a fertility preservation program for children with cancer.

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Journal:  J Assist Reprod Genet       Date:  2021-01-03       Impact factor: 3.412

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