Literature DB >> 27943360

Disease drivers of aging.

Richard J Hodes1, Felipe Sierra1, Steven N Austad2, Elissa Epel3, Gretchen N Neigh4, Kristine M Erlandson5, Marissa J Schafer6, Nathan K LeBrasseur6, Christopher Wiley7, Judith Campisi7, Mary E Sehl8, Rosario Scalia9, Satoru Eguchi9, Balakuntalam S Kasinath10, Jeffrey B Halter11, Harvey Jay Cohen12, Wendy Demark-Wahnefried13, Tim A Ahles14, Nir Barzilai15, Arti Hurria16, Peter W Hunt17.   

Abstract

It has long been known that aging, at both the cellular and organismal levels, contributes to the development and progression of the pathology of many chronic diseases. However, much less research has examined the inverse relationship-the contribution of chronic diseases and their treatments to the progression of aging-related phenotypes. Here, we discuss the impact of three chronic diseases (cancer, HIV/AIDS, and diabetes) and their treatments on aging, putative mechanisms by which these effects are mediated, and the open questions and future research directions required to understand the relationships between these diseases and aging.
© 2016 New York Academy of Sciences.

Entities:  

Keywords:  HIV; age-related; aging; cancer; chronic; diabetes; disease; pathology; prevention

Mesh：

Year:  2016        PMID： 27943360      PMCID： PMC5373660          DOI： 10.1111/nyas.13299

Source DB:  PubMed          Journal:  Ann N Y Acad Sci        ISSN： 0077-8923            Impact factor:   5.691


  153 in total

1.  Calorie restriction enhances cell adaptation to hypoxia through Sirt1-dependent mitochondrial autophagy in mouse aged kidney.

Authors:  Shinji Kume; Takashi Uzu; Kihachiro Horiike; Masami Chin-Kanasaki; Keiji Isshiki; Shin-Ichi Araki; Toshiro Sugimoto; Masakazu Haneda; Atsunori Kashiwagi; Daisuke Koya
Journal:  J Clin Invest       Date:  2010-03-24       Impact factor: 14.808

2.  Epidemiology of heart failure in the United States.

Authors:  R F Gillum
Journal:  Am Heart J       Date:  1993-10       Impact factor: 4.749

3.  Age-associated remodeling of the intestinal epithelial barrier.

Authors:  Lee Tran; Beverley Greenwood-Van Meerveld
Journal:  J Gerontol A Biol Sci Med Sci       Date:  2013-07-20       Impact factor: 6.053

4.  Aging-associated increase in intestinal permeability to polyethylene glycol 900.

Authors:  D Katz; D Hollander; H M Said; V Dadufalza
Journal:  Dig Dis Sci       Date:  1987-03       Impact factor: 3.199

5.  Different mechanisms of endothelial dysfunction with aging and hypertension in rat aorta.

Authors:  C F Küng; T F Lüscher
Journal:  Hypertension       Date:  1995-02       Impact factor: 10.190

6.  Long-term impact of HIV wasting on physical function.

Authors:  Kristine M Erlandson; Xiuhong Li; Alison G Abraham; Joseph B Margolick; Jordan E Lake; Frank J Palella; Susan L Koletar; Todd T Brown
Journal:  AIDS       Date:  2016-01-28       Impact factor: 4.177

7.  Effects of aging and hypertension on endothelium-dependent vascular relaxation in rat carotid artery.

Authors:  K Hongo; T Nakagomi; N F Kassell; T Sasaki; M Lehman; D G Vollmer; T Tsukahara; H Ogawa; J Torner
Journal:  Stroke       Date:  1988-07       Impact factor: 7.914

8.  Evidence that glucose increases monocyte binding to human aortic endothelial cells.

Authors:  J A Kim; J A Berliner; R D Natarajan; J L Nadler
Journal:  Diabetes       Date:  1994-09       Impact factor: 9.461

9.  Acceleration of age-associated methylation patterns in HIV-1-infected adults.

Authors:  Tammy M Rickabaugh; Ruth M Baxter; Mary Sehl; Janet S Sinsheimer; Patricia M Hultin; Lance E Hultin; Austin Quach; Otoniel Martínez-Maza; Steve Horvath; Eric Vilain; Beth D Jamieson
Journal:  PLoS One       Date:  2015-03-25       Impact factor: 3.240

10.  Naturally occurring p16(Ink4a)-positive cells shorten healthy lifespan.

Authors:  Darren J Baker; Bennett G Childs; Matej Durik; Melinde E Wijers; Cynthia J Sieben; Jian Zhong; Rachel A Saltness; Karthik B Jeganathan; Grace Casaclang Verzosa; Abdulmohammad Pezeshki; Khashayarsha Khazaie; Jordan D Miller; Jan M van Deursen
Journal:  Nature       Date:  2016-02-03       Impact factor: 49.962
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  44 in total

1.  A supervised exercise intervention fails to improve depressive symptoms and quality of life among sedentary older adults with HIV infection.

Authors:  DeLayna Goulding; Melissa P Wilson; Samantha MaWhinney; Catherine M Jankowski; Kristine M Erlandson
Journal:  AIDS Care       Date:  2019-06-25

2.  Geroscience and the trans-NIH Geroscience Interest Group, GSIG.

Authors:  Felipe Sierra; Ron Kohanski
Journal:  Geroscience       Date:  2017-02       Impact factor: 7.713

3.  The current understanding of overlap between characteristics of HIV-associated neurocognitive disorders and Alzheimer's disease.

Authors:  Leah H Rubin; Erin E Sundermann; David J Moore
Journal:  J Neurovirol       Date:  2019-01-22       Impact factor: 2.643

Review 4.  Inflammageing: chronic inflammation in ageing, cardiovascular disease, and frailty.

Authors:  Luigi Ferrucci; Elisa Fabbri
Journal:  Nat Rev Cardiol       Date:  2018-09       Impact factor: 32.419

Review 5.  Cardiac tissue remodeling in healthy aging: the road to pathology.

Authors:  Evan Tracy; Gabrielle Rowe; Amanda J LeBlanc
Journal:  Am J Physiol Cell Physiol       Date:  2020-05-20       Impact factor: 4.249

6.  Filgotinib suppresses HIV-1-driven gene transcription by inhibiting HIV-1 splicing and T cell activation.

Authors:  Yang-Hui Jimmy Yeh; Katharine M Jenike; Rachela M Calvi; Jennifer Chiarella; Rebecca Hoh; Steven G Deeks; Ya-Chi Ho
Journal:  J Clin Invest       Date:  2020-09-01       Impact factor: 14.808

7.  Lipoteichoic acid from the cell wall of a heat killed Lactobacillus paracasei D3-5 ameliorates aging-related leaky gut, inflammation and improves physical and cognitive functions: from C. elegans to mice.

Authors:  Shaohua Wang; Shokouh Ahmadi; Ravinder Nagpal; Shalini Jain; Sidharth P Mishra; Kylie Kavanagh; Xuewei Zhu; Zhan Wang; Donald A McClain; Stephen B Kritchevsky; Dalane W Kitzman; Hariom Yadav
Journal:  Geroscience       Date:  2019-12-08       Impact factor: 7.713

8.  Hydrogen Sulfide and the Kidney.

Authors:  Balakuntalam S Kasinath; Hak Joo Lee
Journal:  Adv Exp Med Biol       Date:  2021       Impact factor: 2.622

9.  Aging Research: Collaborations Forge a Promising Future.

Authors:  Melinda S Kelley; Marie A Bernard; Richard J Hodes
Journal:  J Am Geriatr Soc       Date:  2017-08-30       Impact factor: 5.562

10.  Cognitive function prior to systemic therapy and subsequent well-being in older breast cancer survivors: Longitudinal findings from the Thinking and Living with Cancer Study.

Authors:  Lindsay C Kobayashi; Harvey Jay Cohen; Wanting Zhai; Xingtao Zhou; Brent J Small; George Luta; Arti Hurria; Judith Carroll; Danielle Tometich; Brenna C McDonald; Deena Graham; Heather S L Jim; Paul Jacobsen; James C Root; Andrew J Saykin; Tim A Ahles; Jeanne Mandelblatt
Journal:  Psychooncology       Date:  2020-03-17       Impact factor: 3.894
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