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Literature DB >> 27899790

Revisiting unexploited antibiotics in search of new antibacterial drug candidates: the case of MSD-819 (6-chloro-2-quinoxalinecarboxylic acid 1,4-dioxide).

Nicola Ooi¹, Alex J O'Neill¹.

Abstract

Entities: Chemical

Mesh：

Substances：
Anti-Bacterial Agents

Year: 2016 PMID： 27899790 DOI： 10.1038/ja.2016.140

Source DB: PubMed Journal: J Antibiot (Tokyo) ISSN： 0021-8820 Impact factor: 2.649

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15 in total

Review 1. Preclinical evaluation of novel antibacterial agents by microbiological and molecular techniques.

Authors: Alex J O'Neill; Ian Chopra
Journal: Expert Opin Investig Drugs Date: 2004-08 Impact factor: 6.206

Review 2. Bad bugs need drugs: an update on the development pipeline from the Antimicrobial Availability Task Force of the Infectious Diseases Society of America.

Authors: George H Talbot; John Bradley; John E Edwards; David Gilbert; Michael Scheld; John G Bartlett
Journal: Clin Infect Dis Date: 2005-01-25 Impact factor: 9.079

Review 3. Challenges of antibacterial discovery.

Authors: Lynn L Silver
Journal: Clin Microbiol Rev Date: 2011-01 Impact factor: 26.132

Review 4. Platforms for antibiotic discovery.

Authors: Kim Lewis
Journal: Nat Rev Drug Discov Date: 2013-05 Impact factor: 84.694

5. Antibiotic MSD-819. Preparation and properties of biologically active derivatives.

Authors: T W Miller; A K Miller; F J Wolf; E O Stapley; D Hendlin
Journal: J Antibiot (Tokyo) Date: 1969-07 Impact factor: 2.649

6. Anti-staphylococcal activity and mode of action of clofazimine.

Authors: Brunello Oliva; Alexander John O'Neill; Keith Miller; William Stubbings; Ian Chopra
Journal: J Antimicrob Chemother Date: 2004-02-04 Impact factor: 5.790

7. The target of daptomycin is absent from Escherichia coli and other gram-negative pathogens.

Authors: Christopher P Randall; Katherine R Mariner; Ian Chopra; Alex J O'Neill
Journal: Antimicrob Agents Chemother Date: 2012-10-31 Impact factor: 5.191

8. Antibacterial activity and mode of action of tert-butylhydroquinone (TBHQ) and its oxidation product, tert-butylbenzoquinone (TBBQ).

Authors: N Ooi; I Chopra; A Eady; J Cove; R Bojar; A J O'Neill
Journal: J Antimicrob Chemother Date: 2013-03-05 Impact factor: 5.790

Revisiting unexploited antibiotics in search of new antibacterial drug candidates: the case of MSD-819 (6-chloro-2-quinoxalinecarboxylic acid 1,4-dioxide).

Review 1. Preclinical evaluation of novel antibacterial agents by microbiological and molecular techniques.

Review 2. Bad bugs need drugs: an update on the development pipeline from the Antimicrobial Availability Task Force of the Infectious Diseases Society of America.

Review 3. Challenges of antibacterial discovery.

Review 4. Platforms for antibiotic discovery.

5. Antibiotic MSD-819. Preparation and properties of biologically active derivatives.

6. Anti-staphylococcal activity and mode of action of clofazimine.

7. The target of daptomycin is absent from Escherichia coli and other gram-negative pathogens.

8. Antibacterial activity and mode of action of tert-butylhydroquinone (TBHQ) and its oxidation product, tert-butylbenzoquinone (TBBQ).

9. Construction of Escherichia coli K-12 in-frame, single-gene knockout mutants: the Keio collection.

10. Increased mutability of Staphylococci in biofilms as a consequence of oxidative stress.

Review 1. Considerations and Caveats in Combating ESKAPE Pathogens against Nosocomial Infections.

2. Revisiting unexploited antibiotics in search of new antibacterial drug candidates: the case of γ-actinorhodin.