| Literature DB >> 31921562 |
Yu-Xuan Ma1, Chen-Yu Wang1, Yuan-Yuan Li1, Jing Li1, Qian-Qian Wan1, Ji-Hua Chen1, Franklin R Tay1,2, Li-Na Niu1,2.
Abstract
ESKAPE pathogens (Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter species) are among the most common opportunistic pathogens in nosocomial infections. ESKAPE pathogens distinguish themselves from normal ones by developing a high level of antibiotic resistance that involves multiple mechanisms. Contemporary therapeutic strategies which are potential options in combating ESKAPE bacteria need further investigation. Herein, a broad overview of the antimicrobial research on ESKAPE pathogens over the past five years is provided with prospective clinical applications.Entities:
Keywords: antimicrobial peptides; antiresistance; antivirulence; bacteriophages; nanodelivery strategies
Year: 2019 PMID: 31921562 PMCID: PMC6947519 DOI: 10.1002/advs.201901872
Source DB: PubMed Journal: Adv Sci (Weinh) ISSN: 2198-3844 Impact factor: 16.806