Literature DB >> 27885476

Does T2 mapping of the posterior annulus fibrosus indicate the presence of lumbar intervertebral disc herniation? A 3.0 Tesla magnetic resonance study.

Alina Messner1, David Stelzeneder2, Stefan Trattnig1, Götz H Welsch1,3, Martina Schinhan4, Sebastian Apprich4, Martin Brix1,4, Reinhard Windhager4, Siegfried Trattnig1.   

Abstract

PURPOSE: Indicating lumbar disc herniation via magnetic resonance imaging (MRI) T2 mapping in the posterior annulus fibrosus (AF).
METHODS: Sagittal T2 maps of 313 lumbar discs of 64 patients with low back pain were acquired at 3.0 Tesla (3T). The discs were rated according to disc herniation and bulging. Region of interest (ROI) analysis was performed on median, sagittal T2 maps. T2 values of the AF, in the most posterior 10% (PAF-10) and 20% of the disc (PAF-20), were compared.
RESULTS: A significant increase in the T2 values of discs with herniations affecting the imaged area, compared to bulging discs and discs with lateral herniation, was shown in the PAF-10, where no association to the NP was apparent. The PAF-20 exhibited a moderate correlation to the nucleus pulposus (NP).
CONCLUSIONS: High T2 values in the PAF-10 suggest the presence of disc herniation (DH). The results indicate that T2 values in the PAF-20 correspond more to changes in the NP.

Entities:  

Keywords:  Disc signal; Intervertebral disc degeneration; Lumbar spine; Magnetic resonance imaging; Posterior annulus fibrosus; T2 mapping

Mesh:

Year:  2016        PMID: 27885476     DOI: 10.1007/s00586-016-4873-x

Source DB:  PubMed          Journal:  Eur Spine J        ISSN: 0940-6719            Impact factor:   3.134


  29 in total

Review 1.  Clinical practice. Persistent low back pain.

Authors:  Eugene J Carragee
Journal:  N Engl J Med       Date:  2005-05-05       Impact factor: 91.245

2.  T2- and diffusion-maps reveal diurnal changes of intervertebral disc composition: an in vivo MRI study at 1.5 Tesla.

Authors:  Burkhard Ludescher; Julia Effelsberg; Petros Martirosian; Günter Steidle; Bernd Markert; Claus Claussen; Fritz Schick
Journal:  J Magn Reson Imaging       Date:  2008-07       Impact factor: 4.813

3.  Age related reduction of T1rho and T2 magnetic resonance relaxation times of lumbar intervertebral disc.

Authors:  Yi-Xiang J Wang; James F Griffith; Jason C S Leung; Jing Yuan
Journal:  Quant Imaging Med Surg       Date:  2014-08

4.  Quantitative T2 evaluation at 3.0T compared to morphological grading of the lumbar intervertebral disc: a standardized evaluation approach in patients with low back pain.

Authors:  David Stelzeneder; Goetz Hannes Welsch; Balázs Krisztián Kovács; Sabine Goed; Tatjana Paternostro-Sluga; Marianna Vlychou; Klaus Friedrich; Tallal Charles Mamisch; Siegfried Trattnig
Journal:  Eur J Radiol       Date:  2011-02-18       Impact factor: 3.528

5.  3D segmentation of annulus fibrosus and nucleus pulposus from T2-weighted magnetic resonance images.

Authors:  Isaac Castro-Mateos; Jose M Pozo; Peter E Eltes; Luis Del Rio; Aron Lazary; Alejandro F Frangi
Journal:  Phys Med Biol       Date:  2014-12-21       Impact factor: 3.609

6.  Does normalized signal intensity of cervical discs on T2 weighted MRI images change in whiplash patients?

Authors:  Erika J Ulbrich; Javier Añon; Juerg Hodler; Heinz Zimmermann; Matthias Sturzenegger; Suzanne E Anderson; Chris Boesch
Journal:  Injury       Date:  2013-11-20       Impact factor: 2.586

7.  Modified Pfirrmann grading system for lumbar intervertebral disc degeneration.

Authors:  James F Griffith; Yi-Xiang J Wang; Gregory E Antonio; Kai Chow Choi; Alfred Yu; Anil T Ahuja; Ping Chung Leung
Journal:  Spine (Phila Pa 1976)       Date:  2007-11-15       Impact factor: 3.468

8.  Sodium MR imaging of the lumbar intervertebral disk at 7 T: correlation with T2 mapping and modified Pfirrmann score at 3 T--preliminary results.

Authors:  Iris-Melanie Noebauer-Huhmann; Vladimir Juras; Christian W A Pfirrmann; Pavol Szomolanyi; Stefan Zbyn; Alina Messner; Johannes Wimmer; Michael Weber; Klaus M Friedrich; David Stelzeneder; Siegfried Trattnig
Journal:  Radiology       Date:  2012-08-24       Impact factor: 11.105

Review 9.  How should we grade lumbar disc herniation and nerve root compression? A systematic review.

Authors:  Yiping Li; Vance Fredrickson; Daniel K Resnick
Journal:  Clin Orthop Relat Res       Date:  2015-06       Impact factor: 4.176

10.  Quantitative T2 magnetic resonance imaging compared to morphological grading of the early cervical intervertebral disc degeneration: an evaluation approach in asymptomatic young adults.

Authors:  Chun Chen; Minghua Huang; Zhihua Han; Lixin Shao; Yan Xie; Jianhong Wu; Yan Zhang; Hongkui Xin; Aijun Ren; Yong Guo; Deli Wang; Qing He; Dike Ruan
Journal:  PLoS One       Date:  2014-02-03       Impact factor: 3.240

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  9 in total

1.  The importance of level stratification for quantitative MR studies of lumbar intervertebral discs: a cross-sectional analysis in 101 healthy adults.

Authors:  H Hebelka; K Lagerstrand; H Brisby; P J Owen; M J Quittner; T Rantalainen; D L Belavy
Journal:  Eur Spine J       Date:  2019-07-12       Impact factor: 3.134

2.  Axial loading during MRI reveals deviant characteristics within posterior IVD regions between low back pain patients and controls.

Authors:  H Hebelka; L Torén; K Lagerstrand; H Brisby
Journal:  Eur Spine J       Date:  2018-10-09       Impact factor: 3.134

3.  Low back pain patients and controls display functional differences in endplates and vertebrae measured with T2-mapping.

Authors:  K Lagerstrand; H Hebelka; H Brisby
Journal:  Eur Spine J       Date:  2018-11-17       Impact factor: 3.134

Review 4.  Lumbar Disc Herniation.

Authors:  Raj M Amin; Nicholas S Andrade; Brian J Neuman
Journal:  Curr Rev Musculoskelet Med       Date:  2017-12

5.  A comparative study of diffusion kurtosis imaging and T2* mapping in quantitative detection of lumbar intervertebral disk degeneration.

Authors:  Feifei Zeng; Yunfei Zha; Liang Li; Dong Xing; Wei Gong; Lei Hu; Yang Fan
Journal:  Eur Spine J       Date:  2019-05-15       Impact factor: 3.134

6.  Association between MIR31HG polymorphisms and the risk of Lumbar disc herniation in Chinese Han population.

Authors:  Xinglv Hu; Dingjun Hao; Jichao Yin; Futai Gong; Xiangyang Wang; Ruoxi Wang; Bo Liu
Journal:  Cell Cycle       Date:  2022-06-15       Impact factor: 5.173

7.  Prediction of Lumbar Disk Herniation and Clinical Outcome Using Quantitative Magnetic Resonance Imaging: A 5-Year Follow-Up Study.

Authors:  Marcus Raudner; Markus M Schreiner; Vladimir Juras; Michael Weber; David Stelzeneder; Claudia Kronnerwetter; Reinhard Windhager; Siegfried Trattnig
Journal:  Invest Radiol       Date:  2019-03       Impact factor: 6.016

8.  Endoscopic removal of nucleus pulposus of intervertebral disc on lumbar intervertebral disc protrusion and the influence on inflammatory factors and immune function.

Authors:  Gang Xu; Changchun Zhang; Kun Zhu; Zhengqi Bao; Pinghui Zhou; Xiaojun Li
Journal:  Exp Ther Med       Date:  2019-11-19       Impact factor: 2.447

9.  Compositional magnetic resonance imaging in the evaluation of the intervertebral disc: Axial vs sagittal T2 mapping.

Authors:  Marcus Raudner; Markus M Schreiner; Michael Weber; Vladimir Juras; David Stelzeneder; Reinhard Windhager; Siegfried Trattnig
Journal:  J Orthop Res       Date:  2020-06-05       Impact factor: 3.494

  9 in total

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