Emeric Abet1, François Orion2, Fabrice Denimal3, Anne-Géraldine Brau-Weber3, Benoît de Kerviler3, Marc-Henri Jean3, Guillaume Boulanger3, Jérôme Dimet4, Michel Comy3. 1. Digestive Surgery Service, Vendée Hospital Center, Les Oudairies, 85000, La Roche Sur Yon, France. emeric.abet@chd-vendee.fr. 2. Anesthesiology Service, Vendée Hospital Center, 85000, La Roche Sur Yon, France. 3. Digestive Surgery Service, Vendée Hospital Center, Les Oudairies, 85000, La Roche Sur Yon, France. 4. Clinical Research Department, Vendée Hospital Center, 85000, La Roche Sur Yon, France.
Abstract
BACKGROUND: The objective of this study was to evaluate the interest of using ropivacaine for outpatient laparoscopic cholecystectomy. The use of local anesthesia by instillation and infiltration could reduce pain and increase the number of outpatient cholecystectomies. METHODS: A one-center randomized prospective clinical trial compared the use of ropivacaine during outpatient laparoscopic cholecystectomy to the control group of outpatients for laparoscopic cholecystectomy between April 2014 and May 2015. One hundred twenty-four were eligible, and 100 patients were randomized. Patients with outpatient cholecystectomy were randomized into 2 groups: ropivacaine group (Rop group) and control group (control group). We performed a ropivacaine intraperitoneal instillation and wound infiltration for the ropivacaine group at the end of the procedure. The primary observation was authorization for home discharge. The patient was evaluated by the surgeon using the Chung score. Secondary observations included postoperative pain at 2 h post-surgery, at 6 h post-surgery and the day following surgery. RESULTS: Ninety-eight were able to leave on the evening of surgery. At 6 h post-surgery, the Chung score was identical for both groups (p = 0.73). At 2 and 6 h post-surgery and the day following surgery, there was no significant difference in pain levels (p = 0.63; p = 0.61; p = 0.98). Analgesic consumption was no significant difference in the groups. CONCLUSIONS: The use of ropivacaine does not increase the rate of home discharge and does not change the postoperative pain of outpatient cholecystectomy.
RCT Entities:
BACKGROUND: The objective of this study was to evaluate the interest of using ropivacaine for outpatient laparoscopic cholecystectomy. The use of local anesthesia by instillation and infiltration could reduce pain and increase the number of outpatient cholecystectomies. METHODS: A one-center randomized prospective clinical trial compared the use of ropivacaine during outpatient laparoscopic cholecystectomy to the control group of outpatients for laparoscopic cholecystectomy between April 2014 and May 2015. One hundred twenty-four were eligible, and 100 patients were randomized. Patients with outpatient cholecystectomy were randomized into 2 groups: ropivacaine group (Rop group) and control group (control group). We performed a ropivacaine intraperitoneal instillation and wound infiltration for the ropivacaine group at the end of the procedure. The primary observation was authorization for home discharge. The patient was evaluated by the surgeon using the Chung score. Secondary observations included postoperative pain at 2 h post-surgery, at 6 h post-surgery and the day following surgery. RESULTS: Ninety-eight were able to leave on the evening of surgery. At 6 h post-surgery, the Chung score was identical for both groups (p = 0.73). At 2 and 6 h post-surgery and the day following surgery, there was no significant difference in pain levels (p = 0.63; p = 0.61; p = 0.98). Analgesic consumption was no significant difference in the groups. CONCLUSIONS: The use of ropivacaine does not increase the rate of home discharge and does not change the postoperative pain of outpatient cholecystectomy.
Authors: Sandra P Widjaja; Henning Fischer; Alexander R Brunner; Philipp Honigmann; Jürg Metzger Journal: World J Surg Date: 2017-11 Impact factor: 3.352
Authors: Júlio Cezar Uili Coelho; Giuliano Ohde Dalledone; Eduardo Lopes Martins Filho; Eduardo José Brommelstroet Ramos; Marco Aurélio Roeder da Costa; Omar O H M de Loyola E Silva Journal: JSLS Date: 2019 Apr-Jun Impact factor: 2.172