Literature DB >> 27868226

Factors affecting patient reporting of adverse drug reactions: a systematic review.

Rania Al Dweik1, Dawn Stacey2, Dafna Kohen3, Sanni Yaya4.   

Abstract

AIM: The aim of the present study was to determine the barriers and motives influencing consumer reporting of adverse drug reactions (ADRs).
METHODS: A systematic review, guided by the Cochrane Handbook, was conducted. Electronic searches included MEDLINE, EMBASE, PsycINFO, CINAHL, PubMed and the Cochrane Database of Systematic Reviews from 1964 to December 2014. Eligible studies addressed patients' perceptions and factors influencing ADR reporting. Studies about healthcare professional (HCP) reporting of ADRs were excluded. Studies were appraised for quality, and results were analysed descriptively.
RESULTS: Of 1435 citations identified, 21 studies were eligible. Studies were primarily conducted in the UK, the Netherlands and Australia. The identified barriers to patient reporting of ADRs (n = 15 studies) included poor awareness, confusion about who should report the ADR, difficulties with reporting procedures, lack of feedback on submitted reports, mailing costs, ADRs resolved and prior negative reporting experiences. The identified motives for patients reporting ADRs (n = 10 studies) were: preventing others from having similar ADRs, wanting personal feedback, improving medication safety, informing regulatory agencies, improving HCP practices, responding to HCPs not reporting their ADRs and having been asked to report ADRs by HCPs.
CONCLUSIONS: Most patients were not aware of reporting systems and others were confused about reporting. Patients were mainly motivated to make their ADRs known to prevent similar suffering in other patients. By increasing patient familiarity and providing clear reporting processes, reporting systems could better achieve patient reporting of ADRs.
© 2016 The British Pharmacological Society.

Entities:  

Keywords:  adverse drug reaction reporting system; adverse drug reactions; barriers; motives; patient; pharmacovigilance

Mesh:

Year:  2016        PMID: 27868226      PMCID: PMC5346870          DOI: 10.1111/bcp.13159

Source DB:  PubMed          Journal:  Br J Clin Pharmacol        ISSN: 0306-5251            Impact factor:   4.335


  27 in total

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Review 3.  Factors affecting patient reporting of adverse drug reactions: a systematic review.

Authors:  Rania Al Dweik; Dawn Stacey; Dafna Kohen; Sanni Yaya
Journal:  Br J Clin Pharmacol       Date:  2016-11-25       Impact factor: 4.335

4.  A patient's perspective: the impact of adverse drug reactions on patients and their views on reporting.

Authors:  S Lorimer; A Cox; N J Langford
Journal:  J Clin Pharm Ther       Date:  2011-05-18       Impact factor: 2.512

5.  Attitudes and opinion about adverse drug events of women living in a city of south Italy.

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6.  Patients' motives for participating in active post-marketing surveillance.

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9.  Motives for reporting adverse drug reactions by patient-reporters in the Netherlands.

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  30 in total

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Review 3.  Factors affecting patient reporting of adverse drug reactions: a systematic review.

Authors:  Rania Al Dweik; Dawn Stacey; Dafna Kohen; Sanni Yaya
Journal:  Br J Clin Pharmacol       Date:  2016-11-25       Impact factor: 4.335

4.  Development of a Web-Based System to Report Medication-Related Adverse Effects: Design and Usability Study.

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6.  Knowledge of adverse events following immunization, its prevalence and actions of mothers of children aged 0-23 months in a tertiary health institution in Jos, North Central Nigeria.

Authors:  Tolulope O Afolaranmi; Z I Hassan; O Y Sodipo; D Gwomson; O J Ugwu; A O D Ofakunrin; O O Ige; Y O Tagurum; P W Bupwatda
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7.  Dedicated mobile application for drug adverse reaction reporting by patients with relapsing remitting multiple sclerosis (Vigip-SEP study): study protocol for a randomized controlled trial.

Authors:  Gilles Defer; Florian Le Caignec; Sophie Fedrizzi; François Montastruc; Damien Chevanne; Jean-Jacques Parienti; Laure Peyro-Saint-Paul
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8.  Interest in a Mobile App for Two-Way Risk Communication: A Survey Study Among European Healthcare Professionals and Patients.

Authors:  Sieta T de Vries; Petra Denig; Carmen Lasheras Ruiz; François Houÿez; Lisa Wong; Alastair Sutcliffe; Peter G M Mol
Journal:  Drug Saf       Date:  2018-07       Impact factor: 5.606

9.  Descriptions of Adverse Drug Reactions Are Less Informative in Forums Than in the French Pharmacovigilance Database but Provide More Unexpected Reactions.

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Journal:  Front Pharmacol       Date:  2018-05-01       Impact factor: 5.810

10.  Adverse Drug Reaction Reporting in Ethiopia: Systematic Review.

Authors:  Abel Demerew Hailu; Solomon Ahmed Mohammed
Journal:  Biomed Res Int       Date:  2020-08-10       Impact factor: 3.411

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