Ravana Angelini Sfalcin1, Américo Bortolazzo Correr1, Lucas Rafael Morbidelli1, Tatiany Gabrielle Freire Araújo1, Victor Pinheiro Feitosa2, Lourenço Correr-Sobrinho1, Timothy Frederick Watson3, Salvatore Sauro4. 1. Department of Restorative Dentistry, Piracicaba Dental School, University of Campinas-UNICAMP, Limeira Avenue, 901-Piracicaba, São Paulo, Brazil. 2. Department of Restorative Dentistry, School of Pharmacy, Dentistry and Nursing, Federal University of Ceará, Alexandre Baraúna Road, Fortaleza, Ceará, 949, Brazil. 3. King's College London Dental Institute, Tissue Engineering & Biophotonics, London, SE1 9RT, UK. 4. Biomaterials and Minimally Invasive Dentistry-Departamento de Odontologia, Facultad de Ciencias de la Salud, Universidad CEU, Cardenal Herrera, C/Del Pozo s/n, Alfara del Patriarca, Valencia, Spain. salvatore.sauro@uch.ceu.es.
Abstract
OBJECTIVE: This study aimed at evaluating the chemophysical properties of experimental resin infiltrants (ERIs) doped with different bioactive particles. METHODS: A control resin infiltrant (CR) was formulated using triethylene glycol dimethacrylate (TEGDMA) and ethoxylated bisphenol A dimethacrylate (BisEMA). Moreover, five experimental ERIs were also created by incorporating the following bioactive fillers (10 wt%) into the CR: hydroxyapatite (Hap), amorphous calcium phosphate (ACP), zinc-polycarboxylated bioactive glass (BAG-Zn), bioactive glass 45S5 (BAG 45S5), and calcium silicate modified with beta tricalcium phosphate (β-TCP). ICON® resin infiltrant was also used as control. All the ERIs used in this study were assessed for degree of conversion (DC), Knoop microhardness (KHN), softening ratio (SR), tensile cohesive strength (TCS), modulus of elasticity (E-modulus), water sorption (WS), and solubility (SL). Data were subjected to ANOVA and Tukey's test (α = 5%). RESULTS: ICON® presented the lowest DC, KHN, TCS, E-modulus, and SR. Incorporation of bioactive fillers into CR caused significant increase in the KHN. Conversely, no significant effect was observed on DC, TCS, and E-modulus. The resin infiltrant containing Hap showed a significant increase in softening ratio, while, ICON® presented the highest WS and SL. The WS of ACP-doped resin infiltrant was significantly higher than that of the Hap-doped infiltrant. The SL of the ACP-doped infiltrant was higher than CR BAG-Zn or BAG 45S5. CONCLUSION: The incorporation of bioactive particles into experimental resin infiltrants can improve the chemomechanical properties and reduce water sorption and solubility. CLINICAL RELEVANCE: Resin infiltrants doped with bioactive particles may improve the long-term performance of the treatment of white-spot lesions.
OBJECTIVE: This study aimed at evaluating the chemophysical properties of experimental resin infiltrants (ERIs) doped with different bioactive particles. METHODS: A control resin infiltrant (CR) was formulated using triethylene glycol dimethacrylate (TEGDMA) and ethoxylated bisphenol A dimethacrylate (BisEMA). Moreover, five experimental ERIs were also created by incorporating the following bioactive fillers (10 wt%) into the CR: hydroxyapatite (Hap), amorphous calcium phosphate (ACP), zinc-polycarboxylated bioactive glass (BAG-Zn), bioactive glass 45S5 (BAG 45S5), and calcium silicate modified with beta tricalcium phosphate (β-TCP). ICON® resin infiltrant was also used as control. All the ERIs used in this study were assessed for degree of conversion (DC), Knoop microhardness (KHN), softening ratio (SR), tensile cohesive strength (TCS), modulus of elasticity (E-modulus), water sorption (WS), and solubility (SL). Data were subjected to ANOVA and Tukey's test (α = 5%). RESULTS: ICON® presented the lowest DC, KHN, TCS, E-modulus, and SR. Incorporation of bioactive fillers into CR caused significant increase in the KHN. Conversely, no significant effect was observed on DC, TCS, and E-modulus. The resin infiltrant containing Hap showed a significant increase in softening ratio, while, ICON® presented the highest WS and SL. The WS of ACP-doped resin infiltrant was significantly higher than that of the Hap-doped infiltrant. The SL of the ACP-doped infiltrant was higher than CR BAG-Zn or BAG 45S5. CONCLUSION: The incorporation of bioactive particles into experimental resin infiltrants can improve the chemomechanical properties and reduce water sorption and solubility. CLINICAL RELEVANCE: Resin infiltrants doped with bioactive particles may improve the long-term performance of the treatment of white-spot lesions.
Authors: Carmem S Pfeifer; Zachary R Shelton; Roberto R Braga; Dario Windmoller; José C Machado; Jeffrey W Stansbury Journal: Eur Polym J Date: 2011-02-01 Impact factor: 4.598
Authors: Juliana Malacarne; Ricardo M Carvalho; Mario F de Goes; Nadia Svizero; David H Pashley; Franklin R Tay; Cynthia K Yiu; Marcela Rocha de Oliveira Carrilho; Marcela Rocha de Oliveira Carrilho Journal: Dent Mater Date: 2006-01-06 Impact factor: 5.304