Literature DB >> 27833207

Brain death and true patient care.

Doyen Nguyen1.   

Abstract

The "brain death" standard as a criterion of death is closely associated with the need for transplantable organs from heart-beating donors. Are all of these potential donors really dead, or does the documented evidence of patients destined for organ harvesting who improve, or even recover to live normal lives, call into question the premise underlying "brain death"? The aim of this paper is to re-examine the notion of "brain death," especially its clinical test-criteria, in light of a broad framework, including medical knowledge in the field of neuro-intensive care and the traditional ethics of the medical profession. I will argue that both the empirical medical evidence and the ethics of the doctor-patient relationship point to an alternative approach toward the severely comatose patient (potential brain-dead donor). Lay Summary: Though legally accepted and widely practiced, the "brain death" standard for the determination of death has remained a controversial issue, especially in view of the occurrence of "chronic brain death" survivors. This paper critically re-evaluates the clinical test-criteria for "brain death," taking into account what is known about the neuro-critical care of severe brain injury. The medical evidence, together with the understanding of the moral role of the physician toward the patient present before him or her, indicate that an alternative approach should be offered to the deeply comatose patient.

Entities:  

Keywords:  Apnea test; Brain death; Hippocratic ethos; Neuro-intensive care; Severe brain injury

Year:  2016        PMID: 27833207      PMCID: PMC5102188          DOI: 10.1080/00243639.2016.1188472

Source DB:  PubMed          Journal:  Linacre Q        ISSN: 0024-3639


  74 in total

1.  Brain death, the soul, and organic life.

Authors:  Edward J Furton
Journal:  Natl Cathol Bioeth Q       Date:  2002

2.  Mild hypothermia therapy for patients with severe brain injury.

Authors:  Roman Gal; Ivan Cundrle; Iveta Zimova; Martin Smrcka
Journal:  Clin Neurol Neurosurg       Date:  2002-09       Impact factor: 1.876

Review 3.  Toward a virtue-based normative ethics for the health professions.

Authors:  E D Pellegrino
Journal:  Kennedy Inst Ethics J       Date:  1995-09

4.  Post-cardiac arrest syndrome: epidemiology, pathophysiology, treatment, and prognostication. A consensus statement from the International Liaison Committee on Resuscitation (American Heart Association, Australian and New Zealand Council on Resuscitation, European Resuscitation Council, Heart and Stroke Foundation of Canada, InterAmerican Heart Foundation, Resuscitation Council of Asia, and the Resuscitation Council of Southern Africa); the American Heart Association Emergency Cardiovascular Care Committee; the Council on Cardiovascular Surgery and Anesthesia; the Council on Cardiopulmonary, Perioperative, and Critical Care; the Council on Clinical Cardiology; and the Stroke Council.

Authors:  Robert W Neumar; Jerry P Nolan; Christophe Adrie; Mayuki Aibiki; Robert A Berg; Bernd W Böttiger; Clifton Callaway; Robert S B Clark; Romergryko G Geocadin; Edward C Jauch; Karl B Kern; Ivan Laurent; W T Longstreth; Raina M Merchant; Peter Morley; Laurie J Morrison; Vinay Nadkarni; Mary Ann Peberdy; Emanuel P Rivers; Antonio Rodriguez-Nunez; Frank W Sellke; Christian Spaulding; Kjetil Sunde; Terry Vanden Hoek
Journal:  Circulation       Date:  2008-10-23       Impact factor: 29.690

Review 5.  A change of heart and a change of mind? Technology and the redefinition of death in 1968.

Authors:  M Giacomini
Journal:  Soc Sci Med       Date:  1997-05       Impact factor: 4.634

6.  Edmund Pellegrino's philosophy and ethics of medicine: an overview.

Authors:  Daniel P Sulmasy
Journal:  Kennedy Inst Ethics J       Date:  2014-06

Review 7.  Apnea testing during brain death assessment: a review of clinical practice and published literature.

Authors:  J Brady Scott; Michael A Gentile; Stacey N Bennett; MaryAnn Couture; Neil R MacIntyre
Journal:  Respir Care       Date:  2013-03       Impact factor: 2.258

8.  Moderate hypothermia in patients with severe head injury: cerebral and extracerebral effects.

Authors:  C Metz; M Holzschuh; T Bein; C Woertgen; A Frey; I Frey; K Taeger; A Brawanski
Journal:  J Neurosurg       Date:  1996-10       Impact factor: 5.115

9.  End-of-life decision-making in the United States.

Authors:  R D Truog
Journal:  Eur J Anaesthesiol Suppl       Date:  2008

10.  Study on therapeutic mechanism and clinical effect of mild hypothermia in patients with severe head injury.

Authors:  Dashi Zhi; Sai Zhang; Xin Lin
Journal:  Surg Neurol       Date:  2003-05
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  6 in total

Review 1.  [Diagnosis of irreversible loss of brain function ("brain death")-what is new?]

Authors:  Uwe Walter; Stephan A Brandt
Journal:  Nervenarzt       Date:  2019-10       Impact factor: 1.214

2.  Pope John Paul II and the neurological standard for the determination of death: A critical analysis of his address to the Transplantation Society.

Authors:  Doyen Nguyen
Journal:  Linacre Q       Date:  2017-06-01

3.  Evolution of the Criteria of "Brain Death": A Critical Analysis Based on Scientific Realism and Christian Anthropology.

Authors:  Doyen Nguyen
Journal:  Linacre Q       Date:  2019-09-09

4.  Humility before New Scientific Evidence: We No Longer Have Moral Certainty that "Brain Death" Is True Death.

Authors:  Irene Alexander
Journal:  Linacre Q       Date:  2019-09-20

5.  Deceased Organ Transplantation in Bangladesh: The Dynamics of Bioethics, Religion and Culture.

Authors:  Md Sanwar Siraj
Journal:  HEC Forum       Date:  2021-02-17

6.  Does the Uniform Determination of Death Act Need to Be Revised?

Authors:  Doyen Nguyen
Journal:  Linacre Q       Date:  2020-06-02
  6 in total

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