Literature DB >> 27790448

Clinicopathological Characteristics of Thymic Tuberculosis- A Rare Entity.

Keerthi Ramachandran Pillai1, Meenu Prakash1, Muktha Ramesh Pai2.   

Abstract

Tuberculosis is a severely debilitating disease and it rarely presents with involvement of the thymus. Only fifteen cases have been reported worldwide. We report a case of thymic tuberculosis in a 12-year-old female presenting with cervical lymphadenopathy. Computed tomographic imaging revealed a mediastinal mass which was then excised via thoracotomy. The gross appearance of the cut surface of both lobes was variegated with white, granular caseating material. Microscopy revealed multiple, caseating, epithelioid granulomas with dispersed Langhans giant cells surrounded by thymic parenchyma with Hassals corpuscles. The patient was treated with anti-tubercular drugs and her condition improved. On follow up, the patient is healthy and has gained weight.

Entities:  

Keywords:  Caseation; Granuloma; Thymus

Year:  2016        PMID: 27790448      PMCID: PMC5071948          DOI: 10.7860/JCDR/2016/20734.8573

Source DB:  PubMed          Journal:  J Clin Diagn Res        ISSN: 0973-709X


  13 in total

1.  Multilocular tuberculous cyst of thymus gland.

Authors:  Thomas Stephen; Roy Thankachen; Bhawna Parihar; Sheila Nair; Vinayak Shukla
Journal:  J Thorac Cardiovasc Surg       Date:  2003-12       Impact factor: 5.209

2.  Tuberculoma of the mediastinum; report of the first culturally proved case.

Authors:  J W PEABODY; H E WALKUP; J D MURPHY
Journal:  J Thorac Surg       Date:  1958-03

3.  Tuberculosis of the thymus in a 6-month-old infant with literature review.

Authors:  Kanokpan Ruangnapa; Wanaporn Anuntaseree; Somchai Suntornlohanakul
Journal:  Pediatr Infect Dis J       Date:  2014-02       Impact factor: 2.129

4.  Thymic tuberculosis: a case report.

Authors:  T A Simmers; C Jie; M C Sie
Journal:  Neth J Med       Date:  1997-08       Impact factor: 1.422

5.  Thymus tuberculosis poorly responding to anti-mycobacterial therapy in a young girl with primary infection.

Authors:  Oliviero Sacco; Claudio Gambini; Marco Aicardi; Michela Silvestri; Umberto G Rossi; Paolo Tomà; Girolamo Mattioli; Vincenzo Jasonni; Giovanni A Rossi
Journal:  Sarcoidosis Vasc Diffuse Lung Dis       Date:  2004-10       Impact factor: 0.670

Review 6.  Multilocular thymic tuberculosis: case report.

Authors:  S Ganesan; K Ganesan
Journal:  Br J Radiol       Date:  2008-04       Impact factor: 3.039

7.  Thymic tuberculosis preoperatively evaluated with thallium-201 SPECT: two resected cases.

Authors:  Takashi Iwata; Kiyotoshi Inoue; Shinjiro Mizuguchi; Takuma Tsukioka; Ryuhei Morita; Shigefumi Suehiro
Journal:  Ann Thorac Cardiovasc Surg       Date:  2007-02       Impact factor: 1.520

8.  Tuberculosis of the thymus.

Authors:  J M FitzGerald; J R Mayo; R R Miller; W R Jamieson; F Baumgartner
Journal:  Chest       Date:  1992-11       Impact factor: 9.410

9.  Airway obstruction complicating mediastinal tuberculosis: a life-threatening presentation.

Authors:  Wael I Awad; Tracey D Graves; Veronica C White; Kit Wong
Journal:  Ann Thorac Surg       Date:  2002-07       Impact factor: 4.330

10.  Tuberculosis of thymus--a case report.

Authors:  Anil D Prabhu; E T Ismail; Sunil Rajendran; Jiji Thomas; Madhu Kallath; Kannan A Vellachamy; Murali Prabhakaran Vettath
Journal:  Heart Lung Circ       Date:  2007-03-08       Impact factor: 2.975

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  1 in total

1.  Thymoma and Tuberculoma: Unexpected Coexistence.

Authors:  António Grilo Novais; Diana Pinho Santos; Mariana Conceição; Sara Cunha; Joana Capelo; Pedro Crespo; Lina Carvalho
Journal:  Eur J Case Rep Intern Med       Date:  2021-07-30
  1 in total

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