Literature DB >> 27782262

Pyrrolizidine alkaloids: occurrence, biology, and chemical synthesis.

Jeremy Robertson1, Kiri Stevens1.   

Abstract

Covering: 2013 up to the end of 2015This review covers the isolation and structure of new pyrrolizidines; pyrrolizidine biosynthesis; biological activity, including the occurrence of pyrrolizidines as toxic components or contaminants in foods and beverages; and formal and total syntheses of naturally-occurring pyrrolizidine alkaloids and closely related non-natural analogues.

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Year:  2017        PMID： 27782262     DOI： 10.1039/c5np00076a

Source DB:  PubMed          Journal:  Nat Prod Rep        ISSN： 0265-0568            Impact factor:   13.423


  20 in total

Review 1.  Acyclic Twisted Amides.

Authors:  Guangrong Meng; Jin Zhang; Michal Szostak
Journal:  Chem Rev       Date:  2021-08-18       Impact factor: 72.087

2.  Aminoacyl chain translocation catalysed by a type II thioesterase domain in an unusual non-ribosomal peptide synthetase.

Authors:  Shan Wang; William D G Brittain; Qian Zhang; Zhou Lu; Ming Him Tong; Kewen Wu; Kwaku Kyeremeh; Matthew Jenner; Yi Yu; Steven L Cobb; Hai Deng
Journal:  Nat Commun       Date:  2022-01-10       Impact factor: 17.694

3.  Genome Mining and Assembly-Line Biosynthesis of the UCS1025A Pyrrolizidinone Family of Fungal Alkaloids.

Authors:  Li Li; Man-Cheng Tang; Shoubin Tang; Shushan Gao; Sameh Soliman; Leibniz Hang; Wei Xu; Tao Ye; Kenji Watanabe; Yi Tang
Journal:  J Am Chem Soc       Date:  2018-02-02       Impact factor: 15.419

4.  Installation of the Ether Bridge of Lolines by the Iron- and 2-Oxoglutarate-Dependent Oxygenase, LolO: Regio- and Stereochemistry of Sequential Hydroxylation and Oxacyclization Reactions.

Authors:  Juan Pan; Minakshi Bhardwaj; Bo Zhang; Wei-Chen Chang; Christopher L Schardl; Carsten Krebs; Robert B Grossman; J Martin Bollinger
Journal:  Biochemistry       Date:  2018-03-29       Impact factor: 3.162

5.  Highly selective Diels-Alder and Heck arylation reactions in a divergent synthesis of isoindolo- and pyrrolo-fused polycyclic indoles from 2-formylpyrrole.

Authors:  Carlos H Escalante; Eder I Martínez-Mora; Carlos Espinoza-Hicks; Alejandro A Camacho-Dávila; Fernando R Ramos-Morales; Francisco Delgado; Joaquín Tamariz
Journal:  Beilstein J Org Chem       Date:  2020-06-17       Impact factor: 2.883

Review 6.  Pyrrolizidine Alkaloids: Chemistry, Pharmacology, Toxicology and Food Safety.

Authors:  Rute Moreira; David M Pereira; Patrícia Valentão; Paula B Andrade
Journal:  Int J Mol Sci       Date:  2018-06-05       Impact factor: 5.923

7.  Occurrence and Risk Assessment of Pyrrolizidine Alkaloids in Spices and Culinary Herbs from Various Geographical Origins.

Authors:  Florian Kaltner; Michael Rychlik; Manfred Gareis; Christoph Gottschalk
Journal:  Toxins (Basel)       Date:  2020-03-01       Impact factor: 4.546

8.  Asymmetric and Site-Selective [3 + 2]-Annulations for the Synthesis of High-Value Bicyclic Lactams.

Authors:  Dimitris Kalaitzakis; Manolis Sofiadis; Myron Triantafyllakis; Konstantinos Daskalakis; Georgios Vassilikogiannakis
Journal:  Org Lett       Date:  2018-02-08       Impact factor: 6.005

Review 9.  Pyrrolizidine Alkaloids: Biosynthesis, Biological Activities and Occurrence in Crop Plants.

Authors:  Sebastian Schramm; Nikolai Köhler; Wilfried Rozhon
Journal:  Molecules       Date:  2019-01-30       Impact factor: 4.411

10.  Synthesis of Pyrrolidine Monocyclic Analogues of Pochonicine and Its Stereoisomers: Pursuit ofSimplified Structures and Potent β-N-Acetylhexosaminidase Inhibition.

Authors:  Xin Yan; Yuna Shimadate; Atsushi Kato; Yi-Xian Li; Yue-Mei Jia; George W J Fleet; Chu-Yi Yu
Journal:  Molecules       Date:  2020-03-25       Impact factor: 4.411
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