| Literature DB >> 27771931 |
Abstract
Evodiamine (EVO) is a major alkaloid compound extracted from the dry unripened fruit Evodiae fructus (Evodia rutaecarpa Benth., Rutaceae). EVO has a variety of pharmacological activities, such as anti-obesity, anti-allergenic, analgesic, anti-tumor, anti-ulcerogenic, and neuroprotective activities. EVO has varying efficacies in animal models and humans. Here, the physicochemical properties of EVO are presented, and the EVO's functions and mechanisms of action in various chronic diseases are reviewed. EVO is worth exploring in more depth in the future for its potential use in various chronic diseases.Entities:
Keywords: Cell signaling pathways; Chronic diseases; Evodiamine; Mechanisms of action; Pharmacological activities; Physico-chemical properties
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Year: 2016 PMID： 27771931 DOI： 10.1007/978-3-319-41342-6_14
Source DB: PubMed Journal: Adv Exp Med Biol ISSN： 0065-2598 Impact factor: 2.622