Literature DB >> 27746885

Locally Advanced Stage High-Grade Mucoepidermoid Carcinoma of Salivary Gland in a 9-Year-Old Girl: The Controversy of Adjuvant Therapy.

Olga Micol Martínez1, Elena Daghoum Dorado1, María Dolores Amorós García2, María Isabel Oviedo Ramírez3, Isabel de la Fuente Muñoz4, Jose Luis Fuster Soler1.   

Abstract

Malignant salivary gland tumors are rare in children, mostly represented by low-grade mucoepidermoid carcinomas. For these patients, long-term survival rates above 95% are reported after surgical resection. Here we report a case of a 9-year-old girl with a high grade locally advanced mucoepidermoid carcinoma undergoing adjuvant radiotherapy and chemotherapy after surgery. We emphasize the controversy and lack of evidence-based indication for these highly toxic adjuvant therapy modalities in children.

Entities:  

Keywords:  High-grade; carcinoma; children; mucoepidermoyd

Year:  2016        PMID： 27746885      PMCID： PMC5064301          DOI： 10.4081/rt.2016.6429

Source DB:  PubMed          Journal:  Rare Tumors        ISSN： 2036-3605


  19 in total

Review 1.  Mucoepidermoid carcinoma of minor salivary glands: a clinical study of 16 cases and review of the literature.

Authors:  K Triantafillidou; J Dimitrakopoulos; F Iordanidis; D Koufogiannis
Journal:  Oral Dis       Date:  2006-07       Impact factor: 3.511

2.  Head and neck cancers, Version 2.2014. Clinical practice guidelines in oncology.

Authors:  David G Pfister; Sharon Spencer; David M Brizel; Barbara Burtness; Paul M Busse; Jimmy J Caudell; Anthony J Cmelak; A Dimitrios Colevas; Frank Dunphy; David W Eisele; Jill Gilbert; Maura L Gillison; Robert I Haddad; Bruce H Haughey; Wesley L Hicks; Ying J Hitchcock; Antonio Jimeno; Merrill S Kies; William M Lydiatt; Ellie Maghami; Renato Martins; Thomas McCaffrey; Loren K Mell; Bharat B Mittal; Harlan A Pinto; John A Ridge; Cristina P Rodriguez; Sandeep Samant; David E Schuller; Jatin P Shah; Randal S Weber; Gregory T Wolf; Frank Worden; Sue S Yom; Nicole R McMillian; Miranda Hughes
Journal:  J Natl Compr Canc Netw       Date:  2014-10       Impact factor: 11.908

3.  Clinical characteristics and survival for major salivary gland malignancies in children.

Authors:  Nina L Shapiro; Neil Bhattacharyya
Journal:  Otolaryngol Head Neck Surg       Date:  2006-04       Impact factor: 3.497

4.  The role of radiation therapy in pediatric mucoepidermoid carcinomas of the salivary glands.

Authors:  Juliette Thariat; Pierre-Olivier Vedrine; Stephane Temam; Ali Mohamed Ali; Daniel Orbach; Guillaume Odin; Marc Makeieff; Richard Nicollas; Martin Penicaud; Bruno Toussaint; Sebastien Vergez; Anne Laprie; Michel Rives; Karine Montagne; Natacha Teissier; Laurent Castillo
Journal:  J Pediatr       Date:  2012-11-06       Impact factor: 4.406

5.  Epithelial salivary gland tumors in children: a twenty-five-year experience of 122 patients.

Authors:  Qi-Gen Fang; Shuang Shi; Zhen-Ning Li; Xu Zhang; Fa-Yu Liu; Chang-Fu Sun
Journal:  Int J Pediatr Otorhinolaryngol       Date:  2013-06-06       Impact factor: 1.675

6.  Adjuvant chemoradiotherapy for locoregionally advanced and high-risk salivary gland malignancies.

Authors:  Aaron W Pederson; Joseph K Salama; Daniel J Haraf; Mary Ellen Witt; Kerstin M Stenson; Louis Portugal; Tanguy Seiwert; Victoria M Villaflor; Ezra E W Cohen; Everett E Vokes; Elizabeth A Blair
Journal:  Head Neck Oncol       Date:  2011-07-26

Review 7.  Molecular heterogeneity in mucoepidermoid carcinoma: conceptual and practical implications.

Authors:  Diana Bell; Adel K El-Naggar
Journal:  Head Neck Pathol       Date:  2013-03-05

8.  Outcomes of postoperative concurrent chemoradiotherapy for locally advanced major salivary gland carcinoma.

Authors:  Tawee Tanvetyanon; Dahui Qin; Tapan Padhya; Judith McCaffrey; Weiwei Zhu; David Boulware; Ronald DeConti; Andy Trotti
Journal:  Arch Otolaryngol Head Neck Surg       Date:  2009-07

Review 9.  Salivary gland cancers: current treatments, molecular characteristics and new therapies.

Authors:  Sreenivasa R Chandana; Barbara A Conley
Journal:  Expert Rev Anticancer Ther       Date:  2008-04       Impact factor: 4.512

Review 10.  Salivary gland tumors in children: a retrospective clinical review.

Authors:  Ali Varan; Canan Akyüz; Erman Ataş; Taşkın Yücel; Burça Aydın; Bilgehan Yalçın; Tezer Kutluk; Münevver Büyükpamukçu
Journal:  Pediatr Hematol Oncol       Date:  2014-09-23       Impact factor: 1.969
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  1 in total

Review 1.  Advance oropharyngeal mucoepidermoid carcinoma in a 9-year-old boy: A case report and review of literature.

Authors:  Abdulrazak Ajiya; Iliyasu Yunusa Shuaibu; Mansur Adamu Yahuza
Journal:  Afr J Paediatr Surg       Date:  2022 Apr-Jun
  1 in total

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