Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 How 'hidden' reading frames are expressed.

Literature DB >> 2773038

How 'hidden' reading frames are expressed.

Abstract

Secondary reading frames, 'hidden' under other reading frames, are used for coordinated expression of proteins in several eukaryotic viruses. In some genes, ribosomal frameshifting and initiation or reinitiation of protein synthesis on internal AUG codons are translational mechanisms allowing access to such 'hidden' reading frames. In others, secondary reading frames are translated from alternatively spliced or edited mRNAs.

Mesh：

Substances：
RNA, Ribosomal

Year: 1989 PMID： 2773038 PMCID： PMC7172427 DOI： 10.1016/0968-0004(89)90266-1

Source DB: PubMed Journal: Trends Biochem Sci ISSN： 0968-0004 Impact factor: 13.807

33 in total

1. Natural read-through at the UGA termination signal of Q-beta coat protein cistron.

Authors: A M Weiner; K Weber
Journal: Nat New Biol Date: 1971-09-15

2. Slippery runs, shifty stops, backward steps, and forward hops: -2, -1, +1, +2, +5, and +6 ribosomal frameshifting.

Authors: R B Weiss; D M Dunn; J F Atkins; R F Gesteland
Journal: Cold Spring Harb Symp Quant Biol Date: 1987

Review 3. Alternative splicing: a ubiquitous mechanism for the generation of multiple protein isoforms from single genes.

Authors: R E Breitbart; A Andreadis; B Nadal-Ginard
Journal: Annu Rev Biochem Date: 1987 Impact factor: 23.643

4. Sendai virus contains overlapping genes expressed from a single mRNA.

Authors: C Giorgi; B M Blumberg; D Kolakofsky
Journal: Cell Date: 1983-12 Impact factor: 41.582

5. The 2.2 kb E1b mRNA of human Ad12 and Ad5 codes for two tumor antigens starting at different AUG triplets.

Authors: J L Bos; L J Polder; R Bernards; P I Schrier; P J van den Elsen; A J van der Eb; H van Ormondt
Journal: Cell Date: 1981-11 Impact factor: 41.582

6. Activation of double-stranded RNA-dependent kinase (dsl) by the TAR region of HIV-1 mRNA: a novel translational control mechanism.

Authors: I Edery; R Petryshyn; N Sonenberg
Journal: Cell Date: 1989-01-27 Impact factor: 41.582

7. Measles virus editing provides an additional cysteine-rich protein.

Authors: R Cattaneo; K Kaelin; K Baczko; M A Billeter
Journal: Cell Date: 1989-03-10 Impact factor: 41.582

8. Extensive editing of the cytochrome c oxidase III transcript in Trypanosoma brucei.

Authors: J E Feagin; J M Abraham; K Stuart
Journal: Cell Date: 1988-05-06 Impact factor: 41.582

9. Editing of kinetoplastid mitochondrial mRNAs by uridine addition and deletion generates conserved amino acid sequences and AUG initiation codons.

Authors: J M Shaw; J E Feagin; K Stuart; L Simpson
Journal: Cell Date: 1988-05-06 Impact factor: 41.582

10. An efficient ribosomal frame-shifting signal in the polymerase-encoding region of the coronavirus IBV.

Authors: I Brierley; M E Boursnell; M M Binns; B Bilimoria; V C Blok; T D Brown; S C Inglis
Journal: EMBO J Date: 1987-12-01 Impact factor: 11.598

13 in total

1. A root acyl carrier protein-II from spinach is also expressed in leaves and seeds.

Authors: K M Schmid; J B Ohlrogge
Journal: Plant Mol Biol Date: 1990-11 Impact factor: 4.076

2. Autologous chondrocytes versus filtered bone marrow mesenchymal stem/stromal cells for knee cartilage repair-a prospective study.

Authors: David Martinčič; Jure Leban; Giuseppe Filardo; Maurizio Busacca; Ariana Barlič; Matija Veber; Matej Drobnič
Journal: Int Orthop Date: 2020-07-25 Impact factor: 3.075

3. Factors determining the frequency of plasmid cointegrate formation mediated by insertion sequence IS3 from Escherichia coli.

Authors: J Spielmann-Ryser; M Moser; P Kast; H Weber
Journal: Mol Gen Genet Date: 1991-05

How 'hidden' reading frames are expressed.

1. Natural read-through at the UGA termination signal of Q-beta coat protein cistron.

2. Slippery runs, shifty stops, backward steps, and forward hops: -2, -1, +1, +2, +5, and +6 ribosomal frameshifting.

Review 3. Alternative splicing: a ubiquitous mechanism for the generation of multiple protein isoforms from single genes.

4. Sendai virus contains overlapping genes expressed from a single mRNA.

5. The 2.2 kb E1b mRNA of human Ad12 and Ad5 codes for two tumor antigens starting at different AUG triplets.

6. Activation of double-stranded RNA-dependent kinase (dsl) by the TAR region of HIV-1 mRNA: a novel translational control mechanism.

7. Measles virus editing provides an additional cysteine-rich protein.

8. Extensive editing of the cytochrome c oxidase III transcript in Trypanosoma brucei.

9. Editing of kinetoplastid mitochondrial mRNAs by uridine addition and deletion generates conserved amino acid sequences and AUG initiation codons.

10. An efficient ribosomal frame-shifting signal in the polymerase-encoding region of the coronavirus IBV.

1. A root acyl carrier protein-II from spinach is also expressed in leaves and seeds.

2. Autologous chondrocytes versus filtered bone marrow mesenchymal stem/stromal cells for knee cartilage repair-a prospective study.

3. Factors determining the frequency of plasmid cointegrate formation mediated by insertion sequence IS3 from Escherichia coli.

Review 4. Diversity of coding strategies in influenza viruses.

5. Mechanism of translation of monocistronic and multicistronic human immunodeficiency virus type 1 mRNAs.

Review 6. Messenger RNA editing and the genetic code.

7. A gene required for very short patch repair in Escherichia coli is adjacent to the DNA cytosine methylase gene.

Review 8. How does influenza virus regulate gene expression at the level of mRNA translation? Let us count the ways.

9. On the directional specificity of ribosome frameshifting at a "hungry" codon.

10. Dystrophin in frameshift deletion patients with Becker muscular dystrophy.