Ramesh Omranipour1, Ali Kazemian2, Sadaf Alipour1, Masoume Najafi1, Mansour Alidoosti3, Mitra Navid3, Afsaneh Alikhassi4, Nasrin Ahmadinejad4, Khojasteh Bagheri5, Shahrzad Izadi1. 1. Department of Surgical Oncology, Cancer Institute, Tehran University of Medical Science, Tehran, Iran. 2. Department of Radiotherapy Oncology, Cancer Institute, Tehran University of Medical Science, Tehran, Iran. 3. Medical Thermography Department, Fanavaran Madoone Ghermez Company, Tehran, Iran. 4. Department of Radiology, Cancer Institute, Tehran University of Medical Science, Tehran, Iran. 5. Breast Clinic, Cancer Institute, Tehran University of Medical Science, Tehran, Iran.
Abstract
BACKGROUND: Benefits and harms of screening mammography have been disputed in recent years. This fact, along with the limitations of mammography as well as its unavailability in all our medical centers, tempted us to evaluate the accuracy of thermography in detecting breast abnormalities. PATIENTS AND METHODS: All patients who were candidates for breast biopsy were examined by both mammography and thermography before tissue sampling in a referral center between January 2013 and January 2014. We defined sensitivities and specificities, and positive predictive values (PPVs) and negative predictive values (NPVs), of the 2 modalities in comparison with histologic results as the gold standard. RESULTS: 132 patients were included. The median age of all patients was 49.5 ± 10.3 years (range 24-75 years). The sensitivity, specificity, PPV, NPV, and accuracy for mammography were 80.5%, 73.3%, 85.4%, 66.0%, and 76.9%, respectively, whereas for thermography the figures were 81.6%, 57.8%, 78.9%, 61.9%, and 69.7%, respectively. CONCLUSION: Our study confirms that, at the present time, thermography cannot substitute for mammography for the early diagnosis of breast cancer.
BACKGROUND: Benefits and harms of screening mammography have been disputed in recent years. This fact, along with the limitations of mammography as well as its unavailability in all our medical centers, tempted us to evaluate the accuracy of thermography in detecting breast abnormalities. PATIENTS AND METHODS: All patients who were candidates for breast biopsy were examined by both mammography and thermography before tissue sampling in a referral center between January 2013 and January 2014. We defined sensitivities and specificities, and positive predictive values (PPVs) and negative predictive values (NPVs), of the 2 modalities in comparison with histologic results as the gold standard. RESULTS: 132 patients were included. The median age of all patients was 49.5 ± 10.3 years (range 24-75 years). The sensitivity, specificity, PPV, NPV, and accuracy for mammography were 80.5%, 73.3%, 85.4%, 66.0%, and 76.9%, respectively, whereas for thermography the figures were 81.6%, 57.8%, 78.9%, 61.9%, and 69.7%, respectively. CONCLUSION: Our study confirms that, at the present time, thermography cannot substitute for mammography for the early diagnosis of breast cancer.
Entities:
Keywords:
Breast cancer; Infrared; Mammography; Neoplasm; Thermography
Authors: G C Wishart; M Campisi; M Boswell; D Chapman; V Shackleton; S Iddles; A Hallett; P D Britton Journal: Eur J Surg Oncol Date: 2010-05-10 Impact factor: 4.424
Authors: J K Gohagan; N D Rodes; C W Blackwell; W P Darby; C Farrell; T Herder; D K Pearson; E L Spitznagel; M D Wallace Journal: Prev Med Date: 1980-11 Impact factor: 4.018
Authors: A I Faustino-Rocha; A Silva; J Gabriel; C I Teixeira-Guedes; C Lopes; R Gil da Costa; A Gama; R Ferreira; P A Oliveira; M Ginja Journal: Biomed Pharmacother Date: 2013-07-11 Impact factor: 6.529
Authors: Chengli Song; Virginia Appleyard; Karen Murray; Tim Frank; Wilson Sibbett; Alfred Cuschieri; Alastair Thompson Journal: Int J Cancer Date: 2007-09-01 Impact factor: 7.396