Literature DB >> 27704784

Novel Catalyst System for Suzuki-Miyaura Coupling of Challenging DNA-Linked Aryl Chlorides.

Yun Ding1, Jennifer L DeLorey1, Matthew A Clark1.   

Abstract

A novel Pd catalyst system, [(t-Bu)2P(OH)]2PdCl2 (POPd) with the ligand sodium 2'-(dicyclohexylphosphino)-2,6-dimethoxy-[1,1'-biphenyl]-3-sulfonate, is reported. It effectively catalyzes the Suzuki-Miyaura coupling of challenging phenyl chlorides and pyrimidinyl chlorides that are covalently linked to a double-stranded DNA-template with various boronic acids/esters.

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Year:  2016        PMID： 27704784     DOI： 10.1021/acs.bioconjchem.6b00541

Source DB:  PubMed          Journal:  Bioconjug Chem        ISSN： 1043-1802            Impact factor:   4.774


  13 in total

Review 1.  Arylation Chemistry for Bioconjugation.

Authors:  Chi Zhang; Ekaterina V Vinogradova; Alexander M Spokoyny; Stephen L Buchwald; Bradley L Pentelute
Journal:  Angew Chem Int Ed Engl       Date:  2019-02-15       Impact factor: 15.336

2.  Open-Air Alkylation Reactions in Photoredox-Catalyzed DNA-Encoded Library Synthesis.

Authors:  James P Phelan; Simon B Lang; Jaehoon Sim; Simon Berritt; Andrew J Peat; Katelyn Billings; Lijun Fan; Gary A Molander
Journal:  J Am Chem Soc       Date:  2019-02-12       Impact factor: 15.419

3.  DNA-Compatible Suzuki-Miyaura Cross-Coupling Reaction of Aryl Iodides With (Hetero)Aryl Boronic Acids for DNA-Encoded Libraries.

Authors:  Vijay Kumar Siripuram; Yashoda Krishna Sunkari; Thu-Lan Nguyen; Marc Flajolet
Journal:  Front Chem       Date:  2022-06-14       Impact factor: 5.545

4.  Conjugation of oligonucleotides with activated carbamate reagents prepared by the Ugi reaction for oligonucleotide library synthesis.

Authors:  Ryosuke Kita; Takashi Osawa; Satoshi Obika
Journal:  RSC Chem Biol       Date:  2022-04-19

5.  On-DNA Pd and Cu promoted C-N cross-coupling reactions.

Authors:  Xiaojie Lu; Sarah E Roberts; George J Franklin; Christopher P Davie
Journal:  Medchemcomm       Date:  2017-07-12       Impact factor: 3.597

Review 6.  DNA-Encoded Chemistry: Drug Discovery from a Few Good Reactions.

Authors:  Patrick R Fitzgerald; Brian M Paegel
Journal:  Chem Rev       Date:  2020-10-12       Impact factor: 72.087

7.  Palladium-Catalyzed Hydroxycarbonylation of (Hetero)aryl Halides for DNA-Encoded Chemical Library Synthesis.

Authors:  Jian-Yuan Li; Gabriella Miklossy; Ram K Modukuri; Kurt M Bohren; Zhifeng Yu; Murugesan Palaniappan; John C Faver; Kevin Riehle; Martin M Matzuk; Nicholas Simmons
Journal:  Bioconjug Chem       Date:  2019-07-31       Impact factor: 4.774

Review 8.  DNA-encoded libraries (DELs): a review of on-DNA chemistries and their output.

Authors:  Ying Shi; Yan-Ran Wu; Jian-Qiang Yu; Wan-Nian Zhang; Chun-Lin Zhuang
Journal:  RSC Adv       Date:  2021-01-19       Impact factor: 3.361

9.  In-solution direct oxidative coupling for the integration of sulfur/selenium into DNA-encoded chemical libraries.

Authors:  Shilian Yang; Guixian Zhao; Yuting Gao; Yang Sun; Gong Zhang; Xiaohong Fan; Yangfeng Li; Yizhou Li
Journal:  Chem Sci       Date:  2022-02-01       Impact factor: 9.825

10.  Merging C(sp3)-H activation with DNA-encoding.

Authors:  Zhoulong Fan; Shuai Zhao; Tao Liu; Peng-Xiang Shen; Zi-Ning Cui; Zhe Zhuang; Qian Shao; Jason S Chen; Anokha S Ratnayake; Mark E Flanagan; Dominik K Kölmel; David W Piotrowski; Paul Richardson; Jin-Quan Yu
Journal:  Chem Sci       Date:  2020-09-07       Impact factor: 9.825
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