| Literature DB >> 27693432 |
Prina Mehta1, Rita Haj-Ahmad1, Manoochehr Rasekh1, Muhammad S Arshad1, Ashleigh Smith2, Susanna M van der Merwe2, Xiang Li3, Ming-Wei Chang4, Zeeshan Ahmad5.
Abstract
Complex micro- and nano-structures enable crucial developments in the healthcare remit (e.g., pharmaceutical and biomaterial sciences). In recent times, several technologies have been developed and explored to address key healthcare challenges (e.g., advanced chemotherapy, biomedical diagnostics and tissue regeneration). Electrohydrodynamic atomization (EHDA) technologies are rapidly emerging as promising candidates to address these issues. The fundamental principle driving EHDA engineering relates to the action of an electric force (field) on flowing conducting medium (formulation) giving rise to a stable Taylor cone. Through careful optimization of process parameters, material properties and selection, nozzle and needle design, and collection substrate method, complex active micro- and nano-structures are engineered. This short review focuses on key selected recent and established advances in the field of pharmaceutical and biomaterial applications. CrownMesh:
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Year: 2016 PMID: 27693432 DOI: 10.1016/j.drudis.2016.09.021
Source DB: PubMed Journal: Drug Discov Today ISSN: 1359-6446 Impact factor: 7.851