Literature DB >> 27689882

Synthesis and Evaluation of Paclitaxel-Loaded Gold Nanoparticles for Tumor-Targeted Drug Delivery.

Giulio F Paciotti1, Jielu Zhao2, Shugeng Cao2, Peggy J Brodie2, Lawrence Tamarkin1, Marja Huhta1, Lonnie D Myer1, Jay Friedman1, David G I Kingston2.   

Abstract

The synthesis of a series of thiolated paclitaxel analogs is described as part of a novel nanomedicine program aimed at developing formulations of paclitaxel that will bind to gold nanoparticles for tumor targeted drug delivery. Preliminary evaluation of the new nanomedicine composed of 27 nm gold nanoparticles, tumor necrosis factor alpha (TNFα), thiolated polyethylene glycol (PEG-thiol), and one of several thiolated paclitaxel analogs is presented.

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Year:  2016        PMID： 27689882      PMCID： PMC5356508          DOI： 10.1021/acs.bioconjchem.6b00405

Source DB:  PubMed          Journal:  Bioconjug Chem        ISSN： 1043-1802            Impact factor:   4.774


  50 in total

Review 1.  Mechanisms of Taxol resistance related to microtubules.

Authors:  George A Orr; Pascal Verdier-Pinard; Hayley McDaid; Susan Band Horwitz
Journal:  Oncogene       Date:  2003-10-20       Impact factor: 9.867

2.  Survivin is not induced by novel taxanes.

Authors:  Nima Sharifi; Jun Qi; Susan Bane; Shubhada Sharma; Rui Li; Robert Robey; William D Figg; William L Farrar; David G I Kingston
Journal:  Mol Pharm       Date:  2010-10-07       Impact factor: 4.939

Review 3.  Antibody-drug conjugates: current status and future directions.

Authors:  Heidi L Perez; Pina M Cardarelli; Shrikant Deshpande; Sanjeev Gangwar; Gretchen M Schroeder; Gregory D Vite; Robert M Borzilleri
Journal:  Drug Discov Today       Date:  2013-11-15       Impact factor: 7.851

Review 4.  Colloidal gold: a novel nanoparticle for targeted cancer therapeutics.

Authors:  Anathea C Powell; Giulio F Paciotti; Steven K Libutti
Journal:  Methods Mol Biol       Date:  2010

Review 5.  The golden age: gold nanoparticles for biomedicine.

Authors:  Erik C Dreaden; Alaaldin M Alkilany; Xiaohua Huang; Catherine J Murphy; Mostafa A El-Sayed
Journal:  Chem Soc Rev       Date:  2011-11-22       Impact factor: 54.564

6.  Preparation and biological activity of taxol acetates.

Authors:  W Mellado; N F Magri; D G Kingston; R Garcia-Arenas; G A Orr; S B Horwitz
Journal:  Biochem Biophys Res Commun       Date:  1984-10-30       Impact factor: 3.575

Review 7.  Antibody-drug conjugates: an emerging concept in cancer therapy.

Authors:  Ravi V J Chari; Michael L Miller; Wayne C Widdison
Journal:  Angew Chem Int Ed Engl       Date:  2014-02-20       Impact factor: 15.336

8.  Design, synthesis, and bioactivities of steroid-linked taxol analogues as potential targeted drugs for prostate and breast cancer.

Authors:  Changhui Liu; Jeannine S Strobl; Susan Bane; Jennifer K Schilling; Meredith McCracken; Sabarni K Chatterjee; Rayhana Rahim-Bata; David G I Kingston
Journal:  J Nat Prod       Date:  2004-02       Impact factor: 4.050

9.  Reduction of interstitial fluid pressure after TNF-alpha treatment of three human melanoma xenografts.

Authors:  C A Kristensen; M Nozue; Y Boucher; R K Jain
Journal:  Br J Cancer       Date:  1996-08       Impact factor: 7.640

Review 10.  Overview of neuropathy associated with taxanes for the treatment of metastatic breast cancer.

Authors:  Edgardo Rivera; Mary Cianfrocca
Journal:  Cancer Chemother Pharmacol       Date:  2015-01-18       Impact factor: 3.333
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  14 in total

1.  Inhibition of Human Immunodeficiency Virus-1 Integrase by β-Diketo Acid Coated Gold Nanoparticles.

Authors:  Vanna Sanna; Mohamed Fathy Youssef; Nicolino Pala; Dominga Rogolino; Mauro Carcelli; Pankaj Kumar Singh; Tino Sanchez; Nouri Neamati; Mario Sechi
Journal:  ACS Med Chem Lett       Date:  2020-03-20       Impact factor: 4.345

2.  Biogenic synthesis of multifunctional silver nanoparticles from Rhodotorula glutinis and Rhodotorula mucilaginosa: antifungal, catalytic and cytotoxicity activities.

Authors:  Francisco A Cunha; Maria da C S O Cunha; Sabrina M da Frota; Eduardo J J Mallmann; Tiago M Freire; Luelc S Costa; Amauri J Paula; Everardo A Menezes; Pierre B A Fechine
Journal:  World J Microbiol Biotechnol       Date:  2018-08-06       Impact factor: 3.312

3.  ImmunoPET Imaging of Pancreatic Tumors with 89Zr-Labeled Gold Nanoparticle-Antibody Conjugates.

Authors:  Nicholas B Sobol; Joshua A Korsen; Ali Younes; Kimberly J Edwards; Jason S Lewis
Journal:  Mol Imaging Biol       Date:  2020-09-09       Impact factor: 3.488

Review 4.  Engineered Gold-Based Nanomaterials: Morphologies and Functionalities in Biomedical Applications. A Mini Review.

Authors:  Iole Venditti
Journal:  Bioengineering (Basel)       Date:  2019-06-10

5.  The Cytotoxic Effects of Betulin-Conjugated Gold Nanoparticles as Stable Formulations in Normal and Melanoma Cells.

Authors:  Marius Mioc; Ioana Zinuca Pavel; Roxana Ghiulai; Dorina E Coricovac; Claudia Farcaş; Ciprian-Valentin Mihali; Camelia Oprean; Vlad Serafim; Ramona A Popovici; Cristina A Dehelean; Michael I Shtilman; Aristidis M Tsatsakis; Codruţa Şoica
Journal:  Front Pharmacol       Date:  2018-05-03       Impact factor: 5.810

6.  Gold nanoparticles stabilized with βcyclodextrin-2-amino-4-(4-chlorophenyl)thiazole complex: A novel system for drug transport.

Authors:  I Asela; M Noyong; U Simon; J Andrades-Lagos; J Campanini-Salinas; D Vásquez-Velásquez; M Kogan; N Yutronic; R Sierpe
Journal:  PLoS One       Date:  2017-10-11       Impact factor: 3.240

7.  Modulation of the Microtubule Network for Optimization of Nanoparticle Dynamics for the Advancement of Cancer Nanomedicine.

Authors:  Aaron Bannister; Dushanthi Dissanayake; Antonia Kowalewski; Leah Cicon; Kyle Bromma; Devika B Chithrani
Journal:  Bioengineering (Basel)       Date:  2020-06-14

8.  Membrane Surface-Enhanced Raman Spectroscopy for Cholesterol-Modified Lipid Systems: Effect of Gold Nanoparticle Size.

Authors:  Miftah Faried; Keishi Suga; Yukihiro Okamoto; Kamyar Shameli; Mikio Miyake; Hiroshi Umakoshi
Journal:  ACS Omega       Date:  2019-08-19

Review 9.  Nanotechnology-Based Strategies to Develop New Anticancer Therapies.

Authors:  Massimiliano Magro; Andrea Venerando; Alberto Macone; Gianluca Canettieri; Enzo Agostinelli; Fabio Vianello
Journal:  Biomolecules       Date:  2020-05-08

Review 10.  Gold nanoparticle‑mediated delivery of paclitaxel and nucleic acids for cancer therapy (Review).

Authors:  Zhiguang Wang; Jianyu Dong; Qiaojiajie Zhao; Ying Ying; Lijie Zhang; Junrong Zou; Shuqi Zhao; Jiuju Wang; Yuan Zhao; Shanshan Jiang
Journal:  Mol Med Rep       Date:  2020-10-11       Impact factor: 2.952
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