Leonardo Josué Castro-Muñoz1, César Antonio González-Díaz2, Aide Muñoz-Escobar3, Brisna Joana Tovar-Ayona4, Luz María Aguilar-Anguiano5, Rebeca Vargas-Olmos5, Virginia Sánchez-Monroy6. 1. Instituto Politécnico Nacional, Escuela Nacional de Medicina y Homeopatía, Ciudad de México, CP 07320, México. 2. Laboratorio Multidisciplinario de Investigación, Escuela Militar de Graduados de Sanidad, UDEFA, Lomas de San Isidro, Ciudad de México, CP 11620, México; Instituto Politécnico Nacional, Escuela Superior de Medicina, Sección de Posgrado, Ciudad de México, CP 11340, México. 3. Laboratorio Multidisciplinario de Investigación, Escuela Militar de Graduados de Sanidad, UDEFA, Lomas de San Isidro, Ciudad de México, CP 11620, México. 4. Universidad Nacional Autónoma de México, Facultad de Estudios Superiores Cuautitlán Izcalli, Estado de México, CP 54740, México. 5. Universidad del Ejército y Fuerza Aérea Escuela Medico Militar, Lomas de San Isidro, Ciudad de México, CP 11620, México. 6. Laboratorio Multidisciplinario de Investigación, Escuela Militar de Graduados de Sanidad, UDEFA, Lomas de San Isidro, Ciudad de México, CP 11620, México; Instituto Politécnico Nacional, Escuela Nacional de Medicina y Homeopatía, Ciudad de México, CP 07320, México. Electronic address: vickysm17@hotmail.com.
Abstract
OBJETIVE: H. pylori infection is acquired early in life, but symptoms occur mainly in adults. The mode of transmission remains unclear, but several studies have demonstrated that the microorganism may be transmitted orally. H. pylori has been detected in the oral cavity of children, and some authors have studied infection prevalence due to the importance of the bacteria in gastric and extragastric pathology. In México, little is known about H. pylori prevalence in the oral cavity of asymptomatic children, so the aims of this study were to estimate the prevalence of H. pylori in asymptomatic children and evaluate factors associated with the infection. DESING: We studied 162 asymptomatic children of 3.025±1.474 years of age from a kindergarten in México City. Oral swabs, rotating around to cheeks inside of oral cavity were obtained to determine H. pylori, using the polymerase chain reaction for 16S rRNA and glmM genes. RESULTS: We detected a 13% prevalence of H. pylori infection by PCR, and the results were confirmed by sequencing and showed a >97% identity with H. pylori. We observed increased infection with age. No association between H. pylori infection and variables such as sex, family history of gastric diseases, crowding or pets in the home were found. CONCLUSION: H. pylori infection in the oral cavity is frequent among asymptomatic children in México, which represents a risk of infection for other family members and for other children in educational facilities. Early diagnosis is essential for control of the infection and for the development of preventive strategies in childhood. Copyright Â
OBJETIVE: H. pylori infection is acquired early in life, but symptoms occur mainly in adults. The mode of transmission remains unclear, but several studies have demonstrated that the microorganism may be transmitted orally. H. pylori has been detected in the oral cavity of children, and some authors have studied infection prevalence due to the importance of the bacteria in gastric and extragastric pathology. In México, little is known about H. pylori prevalence in the oral cavity of asymptomatic children, so the aims of this study were to estimate the prevalence of H. pylori in asymptomatic children and evaluate factors associated with the infection. DESING: We studied 162 asymptomatic children of 3.025±1.474 years of age from a kindergarten in México City. Oral swabs, rotating around to cheeks inside of oral cavity were obtained to determine H. pylori, using the polymerase chain reaction for 16S rRNA and glmM genes. RESULTS: We detected a 13% prevalence of H. pylori infection by PCR, and the results were confirmed by sequencing and showed a >97% identity with H. pylori. We observed increased infection with age. No association between H. pylori infection and variables such as sex, family history of gastric diseases, crowding or pets in the home were found. CONCLUSION: H. pylori infection in the oral cavity is frequent among asymptomatic children in México, which represents a risk of infection for other family members and for other children in educational facilities. Early diagnosis is essential for control of the infection and for the development of preventive strategies in childhood. Copyright Â
Authors: Alejandra Mendoza-Cantú; Víctor Hugo Urrutia-Baca; Cynthia Sofía Urbina-Ríos; Myriam Angélica De la Garza-Ramos; Martha Elena García-Martínez; Hilda H H Torre-Martínez Journal: Biomed Res Int Date: 2017-11-01 Impact factor: 3.411
Authors: Miguel Angel Aguilar-Luis; Fernando Palacios-Cuervo; Fátima Espinal-Reyes; Andrea Calderón-Rivera; Saúl Levy-Blitchtein; Carlos Palomares-Reyes; Wilmer Silva-Caso; Victor Zavaleta-Gavidia; Jorge Bazán-Mayra; Angela Cornejo-Tapia; Juana Del Valle-Mendoza; Luis J Del Valle Journal: BMC Res Notes Date: 2018-11-14
Authors: Carlos Eduardo Flores-Treviño; Víctor Hugo Urrutia-Baca; Ricardo Gómez-Flores; Myriam Angélica De La Garza-Ramos; María Marisela Sánchez-Chaparro; Mario Alberto Garza-Elizondo Journal: J Dent Sci Date: 2019-03-27 Impact factor: 2.080