Literature DB >> 27655249

When smokers quit: exposure to nicotine and carcinogens persists from thirdhand smoke pollution.

Georg E Matt1, Penelope J E Quintana2, Joy M Zakarian3, Eunha Hoh2, Melbourne F Hovell2, Melinda Mahabee-Gittens4, Kayo Watanabe2, Kathy Datuin2, Cher Vue2, Dale A Chatfield5.   

Abstract

BACKGROUND: Over a 6-month period, we examined tobacco smoke pollutants (also known as thirdhand smoke, THS) that remained in the homes of former smokers and the exposure to these pollutants.
METHODS: 90 smokers completed study measures at baseline (BL). Measures were repeated among verified quitters 1 week (W1), 1 month (M1), 3 months (M3) and 6 months (M6) following cessation. Measures were analysed for THS pollutants on household surfaces, fingers and in dust (ie, nicotine, tobacco-specific nitrosamines) and for urinary markers of exposure (ie, cotinine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL)).
RESULTS: We observed significant short-term reduction of nicotine on surfaces (BL: 22.2 μg/m2, W1: 10.8 μg/m2) and on fingers of non-smoking residents (BL: 29.1 ng/wipe, W1: 9.1 ng/wipe) without further significant changes. Concentrations of nicotine and nicotine-derived nitrosamine ketone (NNK) in dust did not change and remained near BL levels after cessation. Dust nicotine and NNK loadings significantly increased immediately following cessation (nicotine BL: 5.0 μg/m2, W1: 9.3 μg/m2; NNK BL: 11.6 ng/m2, W1: 36.3 ng/m2) before returning to and remaining at near BL levels. Cotinine and NNAL showed significant initial declines (cotinine BL: 4.6 ng/mL, W1: 1.3 ng/mL; NNAL BL: 10.0 pg/mL, W1: 4.2 pg/mL) without further significant changes.
CONCLUSIONS: Homes of smokers remained polluted with THS for up to 6 months after cessation. Residents continued to be exposed to THS toxicants that accumulated in settled house dust and on surfaces before smoking cessation. Further research is needed to better understand the consequences of continued THS exposure after cessation and the efforts necessary to remove THS. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

Entities:  

Keywords:  Carcinogens; Cessation; Cotinine; Nicotine; Secondhand smoke

Mesh:

Substances:

Year:  2016        PMID: 27655249      PMCID: PMC6478602          DOI: 10.1136/tobaccocontrol-2016-053119

Source DB:  PubMed          Journal:  Tob Control        ISSN: 0964-4563            Impact factor:   7.552


  32 in total

1.  Measuring secondhand smoke exposure in babies: the reliability and validity of mother reports in a sample of low-income families.

Authors:  G E Matt; M F Hovell; J M Zakarian; J T Bernert; J L Pirkle; S K Hammond
Journal:  Health Psychol       Date:  2000-05       Impact factor: 4.267

2.  Dynamic behavior of semivolatile organic compounds in indoor air. 2. Nicotine and phenanthrene with carpet and wallboard.

Authors:  M D Van Loy; W J Riley; J M Daisey; W W Nazaroff
Journal:  Environ Sci Technol       Date:  2001-02-01       Impact factor: 9.028

3.  Measuring environmental tobacco smoke exposure in infants and young children through urine cotinine and memory-based parental reports: empirical findings and discussion.

Authors:  G E Matt; D R Wahlgren; M F Hovell; J M Zakarian; J T Bernert; S B Meltzer; J L Pirkle; S Caudill
Journal:  Tob Control       Date:  1999       Impact factor: 7.552

4.  Nicotine derivatives in wastewater and surface waters: application as chemical markers for domestic wastewater.

Authors:  Ignaz J Buerge; Maren Kahle; Hans-Rudolf Buser; Markus D Müller; Thomas Poiger
Journal:  Environ Sci Technol       Date:  2008-09-01       Impact factor: 9.028

5.  Validation of self-reported smoking status using saliva cotinine: a rapid semiquantitative dipstick method.

Authors:  Norman J Montalto; Wayne O Wells
Journal:  Cancer Epidemiol Biomarkers Prev       Date:  2007-09       Impact factor: 4.254

6.  Aggregate exposures of nine preschool children to persistent organic pollutants at day care and at home.

Authors:  Nancy K Wilson; Jane C Chuang; Christopher Lyu; Ronald Menton; Marsha K Morgan
Journal:  J Expo Anal Environ Epidemiol       Date:  2003-05

7.  Exposures of preschool children to chlorpyrifos and its degradation product 3,5,6-trichloro-2-pyridinol in their everyday environments.

Authors:  Marsha K Morgan; Linda S Sheldon; Carry W Croghan; Paul A Jones; Gary L Robertson; Jane C Chuang; Nancy K Wilson; Christopher W Lyu
Journal:  J Expo Anal Environ Epidemiol       Date:  2005-07

8.  Households contaminated by environmental tobacco smoke: sources of infant exposures.

Authors:  G E Matt; P J E Quintana; M F Hovell; J T Bernert; S Song; N Novianti; T Juarez; J Floro; C Gehrman; M Garcia; S Larson
Journal:  Tob Control       Date:  2004-03       Impact factor: 7.552

Review 9.  Tracers for assessing exposure to environmental tobacco smoke: what are they tracing?

Authors:  J M Daisey
Journal:  Environ Health Perspect       Date:  1999-05       Impact factor: 9.031

Review 10.  Biomarkers of environmental tobacco smoke exposure.

Authors:  N L Benowitz
Journal:  Environ Health Perspect       Date:  1999-05       Impact factor: 9.031

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  21 in total

1.  Thirdhand Smoke: New Evidence, Challenges, and Future Directions.

Authors:  Peyton Jacob; Neal L Benowitz; Hugo Destaillats; Lara Gundel; Bo Hang; Manuela Martins-Green; Georg E Matt; Penelope J E Quintana; Jonathan M Samet; Suzaynn F Schick; Prue Talbot; Noel J Aquilina; Melbourne F Hovell; Jian-Hua Mao; Todd P Whitehead
Journal:  Chem Res Toxicol       Date:  2016-12-21       Impact factor: 3.739

2.  Indoor Air Quality and Passive E-cigarette Aerosol Exposures in Vape-Shops.

Authors:  Yeongkwon Son; Daniel P Giovenco; Cristine Delnevo; Andrey Khlystov; Vera Samburova; Qingyu Meng
Journal:  Nicotine Tob Res       Date:  2020-10-08       Impact factor: 4.244

3.  Cotton pillows: A novel field method for assessment of thirdhand smoke pollution.

Authors:  Georg E Matt; Eunha Hoh; Penelope J E Quintana; Joy M Zakarian; Jayson Arceo
Journal:  Environ Res       Date:  2018-09-22       Impact factor: 6.498

4.  Preliminary evidence that high levels of nicotine on children's hands may contribute to overall tobacco smoke exposure.

Authors:  E Melinda Mahabee-Gittens; Ashley L Merianos; Georg E Matt
Journal:  Tob Control       Date:  2017-03-30       Impact factor: 7.552

5.  Nicotine in thirdhand smoke residue predicts relapse from smoking cessation: A pilot study.

Authors:  Georg E Matt; E Melinda Mahabee-Gittens; Joy M Zakarian; Penelope J E Quintana; Eunha Hoh; Mark Myers
Journal:  Addict Behav       Date:  2019-07-02       Impact factor: 3.913

6.  Identification and determination of the volatile organics of third-hand smoke from different cigarettes and clothing fabrics.

Authors:  Elahe Tondro Borujeni; Kamyar Yaghmaian; Kazem Naddafi; Mohammad Sadegh Hassanvand; Maziar Naderi
Journal:  J Environ Health Sci Eng       Date:  2022-02-22

7.  Tobacco smoke exposure in pediatric cystic fibrosis: A qualitative study of clinician and caregiver perspectives on smoking cessation.

Authors:  Gabriela R Oates; William T Harris; Hector H Gutierrez; Cathy Mims; Sarah B Rutland; Corilyn Ott; Soumya J Niranjan; Isabel C Scarinci; Susan C Walley
Journal:  Pediatr Pulmonol       Date:  2020-06-08

8.  E-Liquid Autofluorescence can be used as a Marker of Vaping Deposition and Third-Hand Vape Exposure.

Authors:  Eric S Davis; M Flori Sassano; Henry Goodell; Robert Tarran
Journal:  Sci Rep       Date:  2017-08-07       Impact factor: 4.379

9.  Remediating Thirdhand Smoke Pollution in Multiunit Housing: Temporary Reductions and the Challenges of Persistent Reservoirs.

Authors:  Georg E Matt; Penelope J E Quintana; Eunha Hoh; Joy M Zakarian; Nathan G Dodder; Rachael A Record; Melbourne F Hovell; E Melinda Mahabee-Gittens; Samuel Padilla; Laura Markman; Kayo Watanabe; Thomas E Novotny
Journal:  Nicotine Tob Res       Date:  2021-01-22       Impact factor: 4.244

10.  Association between environmental tobacco smoke exposure across the first four years of life and manifestation of externalizing behavior problems in school-aged children.

Authors:  Lisa Gatzke-Kopp; Michael T Willoughby; Siri Warkentien; Daniel Petrie; Roger Mills-Koonce; Clancy Blair
Journal:  J Child Psychol Psychiatry       Date:  2019-12-03       Impact factor: 8.265

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