Georg E Matt1, E Melinda Mahabee-Gittens2, Joy M Zakarian3, Penelope J E Quintana4, Eunha Hoh4, Mark Myers5. 1. San Diego State University, Department of Psychology, San Diego, CA, USA. Electronic address: gmatt@sdsu.edu. 2. Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH, USA. 3. San Diego State University Research Foundation, San Diego, CA, USA. 4. San Diego State University, School of Public Health, San Diego, CA, USA. 5. Veterans Administration San Diego Healthcare System and Department of Psychiatry, University of California, San Diego, CA, USA.
Abstract
INTRODUCTION: Thirdhand smoke (THS) residue lingers for months in homes of former smokers and may play a role in relapse after smoking cessation. This study examined the association between THS pollution as measured by the level of nicotine in house dust and continued abstinence from smoking. METHODS: Participants were 65 cigarette smokers who reported they were enrolled in any type of smoking cessation program, had set a specific date to quit, and had biochemical verification of continuous abstinence at 1-week (W1), 1-month (M1), 3-months (M3), or 6-months (M6) after their quit date. House dust samples collected at baseline before quitting were analyzed for nicotine concentration (μg/g) and nicotine loading (μg/m2) using liquid chromatography-tandem mass spectrometry (LC-MS/MS). RESULTS: Controlling for age, gender, overall and indoor smoking rates, and years lived in their home, dust nicotine concentration and loading predicted abstinence at W1, M1, M3, and M6. A 10-fold increase in dust nicotine loading and concentration were associated with approximately 50% lower odds of remaining abstinent. CONCLUSIONS: Findings suggest nicotine in house dust may play a role in facilitating relapse after smoking cessation. Additional research is warranted to investigate the causal role of THS residue in homes of former smokers on cravings and continued abstinence.
INTRODUCTION: Thirdhand smoke (THS) residue lingers for months in homes of former smokers and may play a role in relapse after smoking cessation. This study examined the association between THS pollution as measured by the level of nicotine in house dust and continued abstinence from smoking. METHODS:Participants were 65 cigarette smokers who reported they were enrolled in any type of smoking cessation program, had set a specific date to quit, and had biochemical verification of continuous abstinence at 1-week (W1), 1-month (M1), 3-months (M3), or 6-months (M6) after their quit date. House dust samples collected at baseline before quitting were analyzed for nicotineconcentration (μg/g) and nicotine loading (μg/m2) using liquid chromatography-tandem mass spectrometry (LC-MS/MS). RESULTS:Controlling for age, gender, overall and indoor smoking rates, and years lived in their home, dust nicotineconcentration and loading predicted abstinence at W1, M1, M3, and M6. A 10-fold increase in dust nicotine loading and concentration were associated with approximately 50% lower odds of remaining abstinent. CONCLUSIONS: Findings suggest nicotine in house dust may play a role in facilitating relapse after smoking cessation. Additional research is warranted to investigate the causal role of THS residue in homes of former smokers on cravings and continued abstinence.
Authors: Georg E Matt; Penelope J E Quintana; Joy M Zakarian; Addie L Fortmann; Dale A Chatfield; Eunha Hoh; Anna M Uribe; Melbourne F Hovell Journal: Tob Control Date: 2010-10-30 Impact factor: 7.552
Authors: Cynthia A Conklin; Nathalie Robin; Kenneth A Perkins; Ronald P Salkeld; F Joseph McClernon Journal: Exp Clin Psychopharmacol Date: 2008-06 Impact factor: 3.157
Authors: Jessica L Reid; David Hammond; Christian Boudreau; Geoffrey T Fong; Mohammad Siahpush Journal: Nicotine Tob Res Date: 2010-10 Impact factor: 4.244
Authors: Cynthia A Conklin; Kenneth A Perkins; Nathalie Robin; F Joseph McClernon; Ronald P Salkeld Journal: Drug Alcohol Depend Date: 2010-05-26 Impact factor: 4.492
Authors: Georg E Matt; Penelope J E Quintana; Hugo Destaillats; Lara A Gundel; Mohamad Sleiman; Brett C Singer; Peyton Jacob; Neal Benowitz; Jonathan P Winickoff; Virender Rehan; Prue Talbot; Suzaynn Schick; Jonathan Samet; Yinsheng Wang; Bo Hang; Manuela Martins-Green; James F Pankow; Melbourne F Hovell Journal: Environ Health Perspect Date: 2011-05-31 Impact factor: 9.031