Nitin Shivappa1,2,3, James R Hébert1,2,3,4, Monica Ferraroni5, Carlo La Vecchia5, Marta Rossi5. 1. a Cancer Prevention and Control Program , University of South Carolina , Columbia , South Carolina , USA. 2. b Department of Epidemiology and Biostatistics , Arnold School of Public Health, University of South Carolina , Columbia , South Carolina , USA. 3. c Connecting Health Innovations LLC , Columbia , South Carolina , USA. 4. d Department of Family and Preventive Medicine , University of South Carolina School of Medicine , Columbia , South Carolina , USA. 5. e Department of Clinical Sciences and Community Health . Università degli Studi di Milano , Milan , Italy.
Abstract
BACKGROUND: In this study, we explored the association between the dietary inflammatory index (DII) and gastric cancer risk in an Italian case-control study. MATERIALS AND METHODS: Cases were 230 patients with incident, histologically confirmed cases of gastric cancer from the Greater Milan area, Northern Italy. Controls were 547 frequency-matched subjects admitted to the same network of hospitals as cases for a wide spectrum of acute, non-neoplastic conditions. The DII was computed using a reproducible and valid 78-item food frequency questionnaire. Odds ratios (ORs) were estimated through logistic regression models conditioned on age and sex and adjusted for recognized confounding factors, including total energy intake. RESULTS: Subjects with the most pro-inflammatory diet had a higher risk of gastric cancer compared to subjects with the most anti-inflammatory diet (ORQuartile4vs1 = 2.35, 95% confidence interval, 1.32, 4.20; P-trend = 0.004). CONCLUSION: These results indicate that a pro-inflammatory diet, as indicated by higher DII score, was associated with increased risk of gastric cancer.
BACKGROUND: In this study, we explored the association between the dietary inflammatory index (DII) and gastric cancer risk in an Italian case-control study. MATERIALS AND METHODS: Cases were 230 patients with incident, histologically confirmed cases of gastric cancer from the Greater Milan area, Northern Italy. Controls were 547 frequency-matched subjects admitted to the same network of hospitals as cases for a wide spectrum of acute, non-neoplastic conditions. The DII was computed using a reproducible and valid 78-item food frequency questionnaire. Odds ratios (ORs) were estimated through logistic regression models conditioned on age and sex and adjusted for recognized confounding factors, including total energy intake. RESULTS: Subjects with the most pro-inflammatory diet had a higher risk of gastric cancer compared to subjects with the most anti-inflammatory diet (ORQuartile4vs1 = 2.35, 95% confidence interval, 1.32, 4.20; P-trend = 0.004). CONCLUSION: These results indicate that a pro-inflammatory diet, as indicated by higher DII score, was associated with increased risk of gastric cancer.
Authors: Nitin Shivappa; Anna E Prizment; Cindy K Blair; David R Jacobs; Susan E Steck; James R Hébert Journal: Cancer Epidemiol Biomarkers Prev Date: 2014-08-25 Impact factor: 4.254
Authors: Eduardo De Stefani; Pelayo Correa; Paolo Boffetta; Hugo Deneo-Pellegrini; Alvaro L Ronco; María Mendilaharsu Journal: Gastric Cancer Date: 2004 Impact factor: 7.370
Authors: Fred K Tabung; Susan E Steck; Jiajia Zhang; Yunsheng Ma; Angela D Liese; Ilir Agalliu; Melanie Hingle; Lifang Hou; Thomas G Hurley; Li Jiao; Lisa W Martin; Amy E Millen; Hannah L Park; Milagros C Rosal; James M Shikany; Nitin Shivappa; Judith K Ockene; James R Hebert Journal: Ann Epidemiol Date: 2015-03-19 Impact factor: 3.797
Authors: Nitin Shivappa; James R Hébert; Ernst R Rietzschel; Marc L De Buyzere; Michel Langlois; Evi Debruyne; Ascensión Marcos; Inge Huybrechts Journal: Br J Nutr Date: 2015-02-02 Impact factor: 3.718
Authors: Marta Rossi; Valentina Rosato; Cristina Bosetti; Pagona Lagiou; Maria Parpinel; Paola Bertuccio; Eva Negri; Carlo La Vecchia Journal: Cancer Causes Control Date: 2010-06-03 Impact factor: 2.506
Authors: S Franceschi; E Negri; S Salvini; A Decarli; M Ferraroni; R Filiberti; A Giacosa; R Talamini; O Nanni; G Panarello Journal: Eur J Cancer Date: 1993 Impact factor: 9.162
Authors: Nitin Shivappa; Antonella Zucchetto; Maurizio Montella; Diego Serraino; Susan E Steck; Carlo La Vecchia; James R Hébert Journal: Br J Nutr Date: 2015-06-08 Impact factor: 3.718
Authors: Nitin Shivappa; Susan E Steck; Thomas G Hurley; James R Hussey; Yunsheng Ma; Ira S Ockene; Fred Tabung; James R Hébert Journal: Public Health Nutr Date: 2013-10-10 Impact factor: 4.022
Authors: Jacques Ferlay; Isabelle Soerjomataram; Rajesh Dikshit; Sultan Eser; Colin Mathers; Marise Rebelo; Donald Maxwell Parkin; David Forman; Freddie Bray Journal: Int J Cancer Date: 2014-10-09 Impact factor: 7.396
Authors: Nitin Shivappa; Marialaura Bonaccio; James R Hebert; Augusto Di Castelnuovo; Simona Costanzo; Emilia Ruggiero; George Pounis; Maria Benedetta Donati; Giovanni de Gaetano; Licia Iacoviello Journal: Nutrition Date: 2018-04-21 Impact factor: 4.008
Authors: Melissa Lopez-Pentecost; Tracy E Crane; David O Garcia; Lindsay N Kohler; Betsy C Wertheim; James R Hebert; Susan E Steck; Nitin Shivappa; Margarita Santiago-Torres; Marian L Neuhouser; Irene E Hatsu; Linda Snetselaar; Mridul Datta; Candyce H Kroenke; Gloria E Sarto; Cynthia A Thomson Journal: Z Gesundh Wiss Date: 2020-07-14
Authors: Michael D Wirth; Maria Sevoyan; Lorne Hofseth; Nitin Shivappa; Thomas G Hurley; James R Hébert Journal: Brain Behav Immun Date: 2017-12-05 Impact factor: 7.217
Authors: Nitin Shivappa; Camila Niclis; Julia Becaria Coquet; María D Román; James R Hébert; María Del Pilar Diaz Journal: Cancer Causes Control Date: 2018-07-17 Impact factor: 2.506
Authors: Sara Moazzen; Kimberley W J van der Sloot; Roel J Vonk; Geertruida H de Bock; Behrooz Z Alizadeh Journal: Nutrients Date: 2020-06-23 Impact factor: 5.717
Authors: Stina Bodén; Robin Myte; Maria Wennberg; Sophia Harlid; Ingegerd Johansson; Nitin Shivappa; James R Hébert; Bethany Van Guelpen; Lena Maria Nilsson Journal: PLoS One Date: 2019-04-12 Impact factor: 3.240