| Literature DB >> 27586037 |
Tarik Benmarhnia1, Pierre-Alexandre Dionne2, Éric Tchouaket3, Alvine K Fansi4, Astrid Brousselle2.
Abstract
OBJECTIVES: In Quebec, various actors fund activities aimed at increasing physical activity, improving eating habits and reducing smoking. The objective was to evaluate how effective does the healthy lifestyle habits promotion (HLHP) strategy need to be to make to offset its costs.Entities:
Keywords: Attributable fraction; Burden of disease; Economic benefits; Economic evaluation; Health policy; Healthy lifestyle habits promotion; Public health; Return on investment; Risk factors
Mesh:
Year: 2016 PMID: 27586037 PMCID: PMC5288452 DOI: 10.1007/s00038-016-0884-y
Source DB: PubMed Journal: Int J Public Health ISSN: 1661-8556 Impact factor: 3.380
Fig. 1Methodological process. Canada 2016
Fig. 2Logic model of the healthy lifestyle habits promotion strategy in Quebec. Canada 2016
Economic burden of illness by diagnostic category in Quebec
| Code | Cause | Direct costs*, † | |||
|---|---|---|---|---|---|
| Drugs | Hospital care | Medical care | All direct costs | ||
| W000 | All causes | $6,267,268,479 | $10,801,577,118 | $4,647,884,743 | $21,716,730,340 |
| W060 | A. Malignant tumours | ||||
| W064 | 4. Colon and rectal cancer | $3,682,912 | $112,028,852 | $16,223,691 | $131,935,455 |
| W067 | 7. Tracheal, bronchial and lung cancer | $4,750,870 | $123,715,726 | $23,135,123 | $151,601,720 |
| W069 | 9. Breast cancer | $13,768,738 | $42,144,588 | $21,509,603 | $77,422,929 |
| W079 | C. Type 2 diabetes | $147,840,004 | $132,547,663 | $99,296,278 | $379,683,944 |
| W104 | G. Cardiovascular diseases | ||||
| W106 | 2. Hypertensive disease | $741,822,143 | $57,843,016 | $169,159,096 | $968,824,255 |
| W107 | 3. Ischemic heart disease | $290,308,382 | $505,568,277 | $167,814,583 | $963,691,242 |
| W108 | 4. Cerebrovascular disease | $22,588,070 | $396,509,597 | $38,292,634 | $457,390,301 |
| W111 | H. Respiratory conditions | ||||
| W112 | 1. Chronic obstructive pulmonary disease | $83,672,505 | $229,684,077 | $81,379,783 | $394,736,365 |
| W113 | 2. Asthma | $206,389,146 | $69,830,400 | $59,673,740 | $335,893,285 |
| W125 | L. Musculoskeletal diseases | ||||
| W127 | 2. Osteoarthritis (arthrosis) | $57,525,894 | $138,020,356 | $43,047,497 | $238,593,747 |
Canada 2016
* Forecasts based on health expenditure data from Canadian Institute for Health Information (CIHI) and Economic Burden of Illness in Canada (EBIC) data from the Public Health Agency of Canada (Katzmarzyk and Janssen 2004; Kelly et al. 2005; Krueger et al. 2013).
†The chronic diseases selected in our economic model (subcategories A4, A7, A9, C, G2, G3, G4, H1, H2, L2) were responsible for $4.161 billion of direct healthcare spending in 2010
Assessment of Population attributable fractions (PAF) of total direct healthcare costs
| Chronic diseases | Risk factors (RF) | Men | Women | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| RRa | (95 % CIb) |
| Adj. PAFd (%) | RRa | (95 % CIb) |
| Adj. PAFd (%) | ||||
| (1) Pulmonary diseases | |||||||||||
| Chronic obstructive pulmonary disease | Smoker | 4.11 | 3.28 | 5.15 | 18.9 | 59.9 | 3.28 | 2.35 | 4.58 | 15.7 | 39.4 |
| Occasional smoker | 2.14 | 1.87 | 2.46 | 6.3 | 2.14 | 1.87 | 2.46 | 4.9 | |||
| Former smoker | 2.97 | 2.63 | 3.34 | 42.3 | 1.61 | 1.46 | 1.77 | 38.8 | |||
| Insufficient consumption of fruits and vegetables | 1.32 | 1.09 | 1.67 | 56.7 | 15.2 | 1.32 | 1.09 | 1.67 | 39.7 | 11.1 | |
| Asthma | Smoker | 1.70 | 1.30 | 2.20 | 18.9 | 13.6 | 1.30 | 0.80 | 2.30 | 15.7 | 6.3 |
| Occasional smoker | 1.40 | 1.20 | 1.60 | 6.3 | 1.40 | 1.20 | 1.60 | 4.9 | |||
| Obesity | 1.43 | 1.14 | 1.79 | 17.5 | 13.6 | 1.78 | 1.36 | 2.32 | 15.4 | 15.8 | |
| Overweight | 1.20 | 1.08 | 1.33 | 41.0 | 1.25 | 1.05 | 1.49 | 27.1 | |||
| (2) Cancers | |||||||||||
| Lung cancer | Smoker | 8.96 | 6.63 | 12.1 | 18.9 | 73.0 | 7.58 | 5.36 | 10.7 | 15.7 | 68.1 |
| Former smoker | 3.85 | 2.77 | 5.34 | 42.3 | 3.85 | 2.77 | 5.34 | 38.8 | |||
| Insufficient consumption of fruits and vegetables | 1.21 | 1.04 | 1.45 | 56.7 | 10.6 | 1.21 | 1.04 | 1.45 | 39.7 | 7.7 | |
| Breast cancer | Physical inactivity | 1.49 | 1.00 | 2.27 | 63.5 | 23.7 | |||||
| Insufficient consumption of fruits and vegetables | 1.12 | 1.01 | 1.25 | 39.7 | 4.5 | ||||||
| Post-menopausal breast cancer | Obesity | 1.15 | 1.08 | 1.23 | 15.4 | 4.3 | |||||
| Overweight | 1.08 | 1.03 | 1.23 | 27.1 | |||||||
| Colon and rectum cancer | Obesity | 1.95 | 1.59 | 2.39 | 17.5 | 27.3 | 1.66 | 1.52 | 1.81 | 15.4 | 18.3 |
| Overweight | 1.51 | 1.37 | 1.67 | 41.0 | 1.45 | 1.30 | 1.62 | 27.1 | |||
| Physical inactivity | 1.26 | 1.10 | 1.47 | 58.2 | 13.1 | 1.40 | 1.13 | 1.74 | 63.5 | 20.3 | |
| (3) Cardiovascular diseases | |||||||||||
| Stroke | Obesity | 1.26 | 1.07 | 1.48 | 17.5 | 6.2 | 1.26 | 1.07 | 1.48 | 15.4 | 5.1 |
| Overweight | 1.05 | 0.93 | 1.17 | 41.0 | 1.05 | 0.93 | 1.17 | 27.1 | |||
| Insufficient consumption of fruits and vegetables | 1.20 | 1.12 | 1.30 | 56.7 | 10.4 | 1.05 | 0.96 | 1.14 | 39.7 | 2.0 | |
| Physical inactivity | 1.25 | 1.15 | 1.35 | 58.2 | 12.7 | 1.22 | 1.14 | 1.32 | 63.5 | 12.3 | |
| Smoker | 1.43 | 1.35 | 1.52 | 25.2 | 15.3 | 1.72 | 1.59 | 1.86 | 20.6 | 17.6 | |
| Former smoker | 1.17 | 1.05 | 1.88 | 42.3 | 1.17 | 1.05 | 1.88 | 38.8 | |||
| Ischemic heart diseases | Obesity | 1.72 | 1.51 | 2.24 | 17.5 | 19.7 | 3.10 | 2.81 | 3.43 | 15.4 | 35.1 |
| Overweight | 1.29 | 1.18 | 1.41 | 41.0 | 1.80 | 1.64 | 1.98 | 27.1 | |||
| Insufficient consumption of fruits and vegetables | 1.11 | 1.02 | 1.22 | 56.7 | 5.9 | 1.32 | 0.95 | 1.82 | 39.7 | 11.1 | |
| Physical inactivity | 1.10 | 0.96 | 1.30 | 58.2 | 5.5 | 1.25 | 1.09 | 1.45 | 63.5 | 13.7 | |
| Smoker | 1.60 | 1.26 | 2.02 | 25.2 | 12.8 | 3.22 | 2.47 | 4.22 | 20.6 | 34.0 | |
| Former smoker | 0.99 | 0.69 | 1.42 | 42.3 | 1.15 | 0.92 | 1.44 | 38.8 | |||
| Hypertension | Obesity | 1.84 | 1.51 | 2.24 | 17.5 | 20.7 | 2.42 | 1.59 | 3.67 | 15.4 | 28.3 |
| Overweight | 1.28 | 1.10 | 1.50 | 41.0 | 1.65 | 1.24 | 2.19 | 27.1 | |||
| Physical inactivity | 1.47 | 1.11 | 2.70 | 58.2 | 21.5 | 1.47 | 1.11 | 2.70 | 63.5 | 23.0 | |
| Smoker | 1.15 | 1.03 | 1.27 | 25.2 | 6.7 | 1.15 | 1.03 | 1.27 | 20.6 | 5.8 | |
| Former smoker | 1.08 | 1.01 | 1.15 | 42.3 | 1.08 | 1.01 | 1.15 | 38.8 | |||
| (4) Metabolic diseases | |||||||||||
| Type II diabetes | Obesity | 6.48 | 5.17 | 8.13 | 17.5 | 61.9 | 8.38 | 5.46 | 12.85 | 15.4 | 65.1 |
| Overweight | 2.63 | 2.09 | 3.32 | 41.0 | 3.69 | 2.52 | 5.40 | 27.1 | |||
| Insufficient consumption of fruits and vegetables | 1.20 | 1.11 | 1.32 | 58.2 | 10.4 | 1.20 | 1.11 | 1.32 | 63.5 | 11.3 | |
| Physical inactivity | 1.04 | 0.85 | 1.27 | 56.7 | 2.2 | 1.04 | 0.85 | 1.27 | 39.7 | 1.6 | |
| (5) Musculoskeletal diseases | |||||||||||
| Osteoarthritis | Obesity | 4.20 | 2.76 | 6.41 | 17.5 | 56.2 | 1.96 | 1.88 | 2.04 | 15.4 | 26.7 |
| Overweight | 2.76 | 2.05 | 3.70 | 41.0 | 1.80 | 1.75 | 1.85 | 27.1 | |||
Canada 2016
aRelative risk
bConfidence interval
cPrevalence
dPopulation attributable fraction
Direct healthcare costs associated to lifestyle-related risk factors
| Chronic diseases | Direct healthcare costs (CAN $2010) | Risk factors (RF) | Adj. PAFa (%) | Costs attributable to risk factors ($) | Total costs adjusted for multiple exposition ($) |
|---|---|---|---|---|---|
| (1) Pulmonary diseases | |||||
| Chronic Obstructive Pulmonary disease | $394,736,365 | Smoking | 49.52 | $195,464,225 | $221,658,019 |
| Insufficient consumption of fruits and vegetables | 13.14 | $51,887,048 | |||
| Asthma | $335,893,285 | Smoking | 9.88 | $33,195,061 | $77,751,443 |
| Obesity and overweight | 14.72 | $49,442,607 | |||
| (2) Cancers | |||||
| Lung cancers | $151,601,720 | Smoking | 70.56 | $106,973,175 | $111,056,160 |
| Insufficient consumption of fruits and vegetables | 9.15 | $13,869,767 | |||
| Breast cancers | $77,422,929 | Physical inactivity | 4.55 | $3,520,702 | $21,058,496 |
| Insufficient consumption of fruits and vegetables | 23.73 | $18,373,294 | |||
| Post-menopausal breast cancers | $61,164,114 | Obesity and overweight | 4.29 | $2,621,537 | $2,621,537 |
| Colon and rectum cancers | $131,935,455 | Obesity and overweight | 22.71 | $29,963,004 | $47,049,393 |
| Physical inactivity | 16.76 | $22,106,957 | |||
| (3) Cardiovascular diseases | |||||
| Stroke | $457,390,301 | Smoking | 16.48 | $75,356,930 | $161,321,080 |
| Insufficient consumption of fruits and vegetables | 6.17 | $28,230,351 | |||
| Physical inactivity | 12.48 | $57,064,937 | |||
| Obesity and overweight | 5.63 | $25,751,457 | |||
| Ischemic heart diseases | $963,691,242 | Smoking | 23.55 | $226,961,558 | $522,497,040 |
| Insufficient consumption of fruits and vegetables | 8.57 | $82,558,945 | |||
| Physical inactivity | 9.67 | $93,144,537 | |||
| Obesity and overweight | 27.50 | $264,972,860 | |||
| Hypertension | $968,824,255 | Smoking | 6.25 | $60,584,638 | $436,253,706 |
| Insufficient consumption of fruits and vegetables | 22.24 | $215,504,459 | |||
| Obesity and overweight | 24.59 | $238,211,364 | |||
| (4) Metabolic disease | |||||
| Type II diabetes | $379,683,944 | Insufficient consumption of fruits and vegetables | 1.89 | $7,161,712 | $258,622,744 |
| Physical inactivity | 10.85 | $41,212,151 | |||
| Obesity and overweight | 63.55 | $241,271,621 | |||
| (5) Musculoskeletal diseases | |||||
| Osteoarthritis | $238,593,747 | Obesity and overweight | 41.21 | $98,326,933 | $98,326,933 |
| Direct costs of chronic diseases | $4,160,937,358 | Total costs attributable to risk factors | $1,958,216,550 | ||
Canada 2016
aPopulation attributable fraction