Literature DB >> 27573382

Understanding how mismatch repair proteins participate in the repair/anti-recombination decision.

Ujani Chakraborty1, Eric Alani2.   

Abstract

Mismatch repair (MMR) systems correct DNA mismatches that result from DNA polymerase misincorporation errors. Mismatches also appear in heteroduplex DNA intermediates formed during recombination between nearly identical sequences, and can be corrected by MMR or removed through an unwinding mechanism, known as anti-recombination or heteroduplex rejection. We review studies, primarily in baker's yeast, which support how specific factors can regulate the MMR/anti-recombination decision. Based on recent advances, we present models for how DNA structure, relative amounts of key repair proteins, the timely localization of repair proteins to DNA substrates and epigenetic marks can modulate this critical decision. © FEMS 2016. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Entities:  

Keywords:  DNA mismatch repair; Msh2; Msh3; Msh6; chromatin marks; heteroduplex rejection

Year:  2016        PMID： 27573382      PMCID： PMC5976031          DOI： 10.1093/femsyr/fow071

Source DB:  PubMed          Journal:  FEMS Yeast Res        ISSN： 1567-1356            Impact factor:   2.796


  114 in total

1.  The cell cycle and DNA mismatch repair.

Authors:  Allen G Schroering; Michael A Edelbrock; Timothy J Richards; Kandace J Williams
Journal:  Exp Cell Res       Date:  2006-10-26       Impact factor: 3.905

2.  The full-length Saccharomyces cerevisiae Sgs1 protein is a vigorous DNA helicase that preferentially unwinds holliday junctions.

Authors:  Petr Cejka; Stephen C Kowalczykowski
Journal:  J Biol Chem       Date:  2010-01-19       Impact factor: 5.157

3.  HDAC6-p97/VCP controlled polyubiquitin chain turnover.

Authors:  Cyril Boyault; Benoit Gilquin; Yu Zhang; Vladimir Rybin; Elspeth Garman; Wolfram Meyer-Klaucke; Patrick Matthias; Christoph W Müller; Saadi Khochbin
Journal:  EMBO J       Date:  2006-06-29       Impact factor: 11.598

4.  The yeast histone chaperone chromatin assembly factor 1 protects against double-strand DNA-damaging agents.

Authors:  Jeffrey Linger; Jessica K Tyler
Journal:  Genetics       Date:  2005-09-02       Impact factor: 4.562

5.  Alleles of the yeast Pms1 mismatch-repair gene that differentially affect recombination- and replication-related processes.

Authors:  Caroline Welz-Voegele; Jana E Stone; Phuoc T Tran; Hutton M Kearney; R Michael Liskay; Thomas D Petes; Sue Jinks-Robertson
Journal:  Genetics       Date:  2002-11       Impact factor: 4.562

6.  Sequence composition and context effects on the generation and repair of frameshift intermediates in mononucleotide runs in Saccharomyces cerevisiae.

Authors:  B D Harfe; S Jinks-Robertson
Journal:  Genetics       Date:  2000-10       Impact factor: 4.562

7.  Histone deacetylase 6 binds polyubiquitin through its zinc finger (PAZ domain) and copurifies with deubiquitinating enzymes.

Authors:  Sara S Hook; Amir Orian; Shaun M Cowley; Robert N Eisenman
Journal:  Proc Natl Acad Sci U S A       Date:  2002-09-27       Impact factor: 11.205

8.  Mismatch repair proteins regulate heteroduplex formation during mitotic recombination in yeast.

Authors:  W Chen; S Jinks-Robertson
Journal:  Mol Cell Biol       Date:  1998-11       Impact factor: 4.272

9.  Isolation and characterization of new proliferating cell nuclear antigen (POL30) mutator mutants that are defective in DNA mismatch repair.

Authors:  Patrick J Lau; Hernan Flores-Rozas; Richard D Kolodner
Journal:  Mol Cell Biol       Date:  2002-10       Impact factor: 4.272

10.  Physical and functional interactions between Werner syndrome helicase and mismatch-repair initiation factors.

Authors:  Nurten Saydam; Radhakrishnan Kanagaraj; Tobias Dietschy; Patrick L Garcia; Javier Peña-Diaz; Igor Shevelev; Igor Stagljar; Pavel Janscak
Journal:  Nucleic Acids Res       Date:  2007-08-22       Impact factor: 16.971
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  33 in total

1.  Genomic Instability Promoted by Overexpression of Mismatch Repair Factors in Yeast: A Model for Understanding Cancer Progression.

Authors:  Ujani Chakraborty; Timothy A Dinh; Eric Alani
Journal:  Genetics       Date:  2018-04-13       Impact factor: 4.562

2.  Chromatin Modifiers Alter Recombination Between Divergent DNA Sequences.

Authors:  Ujani Chakraborty; Beata Mackenroth; David Shalloway; Eric Alani
Journal:  Genetics       Date:  2019-06-20       Impact factor: 4.562

3.  Mechanistic Insight into Crossing over during Mouse Meiosis.

Authors:  Shaun E Peterson; Scott Keeney; Maria Jasin
Journal:  Mol Cell       Date:  2020-05-01       Impact factor: 17.970

4.  Precise genome engineering in Drosophila using prime editing.

Authors:  Justin A Bosch; Gabriel Birchak; Norbert Perrimon
Journal:  Proc Natl Acad Sci U S A       Date:  2021-01-05       Impact factor: 11.205

5.  Dynamic human MutSα-MutLα complexes compact mismatched DNA.

Authors:  Kira C Bradford; Hunter Wilkins; Pengyu Hao; Zimeng M Li; Bangchen Wang; Dan Burke; Dong Wu; Austin E Smith; Logan Spaller; Chunwei Du; Jacob W Gauer; Edward Chan; Peggy Hsieh; Keith R Weninger; Dorothy A Erie
Journal:  Proc Natl Acad Sci U S A       Date:  2020-06-25       Impact factor: 11.205

Review 6.  Repair of DNA double-strand breaks in plant meiosis: role of eukaryotic RecA recombinases and their modulators.

Authors:  Côme Emmenecker; Christine Mézard; Rajeev Kumar
Journal:  Plant Reprod       Date:  2022-06-01       Impact factor: 3.767

7.  Multi-omics data integration analysis identifies the spliceosome as a key regulator of DNA double-strand break repair.

Authors:  Dana Sherill-Rofe; Oded Raban; Steven Findlay; Dolev Rahat; Irene Unterman; Arash Samiei; Amber Yasmeen; Zafir Kaiser; Hellen Kuasne; Morag Park; William D Foulkes; Idit Bloch; Aviad Zick; Walter H Gotlieb; Yuval Tabach; Alexandre Orthwein
Journal:  NAR Cancer       Date:  2022-04-08

Review 8.  Expanded roles for the MutL family of DNA mismatch repair proteins.

Authors:  Christopher M Furman; Ryan Elbashir; Eric Alani
Journal:  Yeast       Date:  2020-07-30       Impact factor: 3.239

Review 9.  Collaborations between chromatin and nuclear architecture to optimize DNA repair fidelity.

Authors:  Beata Mackenroth; Eric Alani
Journal:  DNA Repair (Amst)       Date:  2020-11-22

Review 10.  DNA damage repair: historical perspectives, mechanistic pathways and clinical translation for targeted cancer therapy.

Authors:  Ruixue Huang; Ping-Kun Zhou
Journal:  Signal Transduct Target Ther       Date:  2021-07-09
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