Literature DB >> 27538469

Structural Diversity and Biological Activities of Indole Diketopiperazine Alkaloids from Fungi.

Yang-Min Ma1, Xi-Ai Liang1, Yang Kong1, Bin Jia1.   

Abstract

Indole diketopiperazine alkaloids are secondary metabolites of microorganisms that are widely distributed in filamentous fungi, especially in the genera Aspergillus and Penicillium of the phylum Ascomycota or sac fungi. These alkaloids represent a group of natural products characterized by diversity in both chemical structures and biological activities. This review aims to summarize 166 indole diketopiperazine alkaloids from fungi published from 1944 to mid-2015. The emphasis is on diverse chemical structures within these alkaloids and their relevant biological activities. The aim is to assess which of these compounds merit further study for purposes of drug development.

Entities:  

Keywords:  biological activity; fungi; indole diketopiperazine alkaloids; natural product; structural diversity

Mesh：

Substances：

Year:  2016        PMID： 27538469     DOI： 10.1021/acs.jafc.6b01772

Source DB:  PubMed          Journal:  J Agric Food Chem        ISSN： 0021-8561            Impact factor:   5.279


  28 in total

1.  2,5-Diketopiperazines From a Sponge-Derived Fungus Aspergillus sclerotiorum.

Authors:  Chao-Yi Wang; Xiao-Han Liu; Yao-Yao Zheng; Xing-Yan Ning; Ya-Hui Zhang; Xiu-Mei Fu; Xin Li; Chang-Lun Shao; Chang-Yun Wang
Journal:  Front Microbiol       Date:  2022-05-20       Impact factor: 6.064

2.  Efficient production of a cyclic dipeptide (cyclo-TA) using heterologous expression system of filamentous fungus Aspergillus oryzae.

Authors:  Jianzhao Qi; Haiyan Han; Dan Sui; Shengnan Tan; Changli Liu; Pengchao Wang; Chunliang Xie; Xuekui Xia; Jin-Ming Gao; Chengwei Liu
Journal:  Microb Cell Fact       Date:  2022-07-18       Impact factor: 6.352

Review 3.  Natural Products Research in China From 2015 to 2016.

Authors:  Haishan Liu; Guoliang Zhu; Yaqin Fan; Yuqi Du; Mengmeng Lan; Yibo Xu; Weiming Zhu
Journal:  Front Chem       Date:  2018-03-20       Impact factor: 5.221

4.  Indolediketopiperazine Alkaloids from Eurotium cristatum EN-220, an Endophytic Fungus Isolated from the Marine Alga Sargassum thunbergii.

Authors:  Feng-Yu Du; Xin Li; Xiao-Ming Li; Li-Wei Zhu; Bin-Gui Wang
Journal:  Mar Drugs       Date:  2017-01-25       Impact factor: 5.118

5.  Bioactive Indolyl Diketopiperazines from the Marine Derived Endophytic Aspergillus versicolor DY180635.

Authors:  Yi Ding; Xiaojing Zhu; Liling Hao; Mengyao Zhao; Qiang Hua; Faliang An
Journal:  Mar Drugs       Date:  2020-06-28       Impact factor: 5.118

Review 6.  Diketopiperazine Gels: New Horizons from the Self-Assembly of Cyclic Dipeptides.

Authors:  Marco Scarel; Silvia Marchesan
Journal:  Molecules       Date:  2021-06-03       Impact factor: 4.411

7.  Eurotiumins A⁻E, Five New Alkaloids from the Marine-Derived Fungus Eurotium sp. SCSIO F452.

Authors:  Wei-Mao Zhong; Jun-Feng Wang; Xue-Feng Shi; Xiao-Yi Wei; Yu-Chan Chen; Qi Zeng; Yao Xiang; Xia-Yu Chen; Xin-Peng Tian; Zhi-Hui Xiao; Wei-Min Zhang; Fa-Zuo Wang; Si Zhang
Journal:  Mar Drugs       Date:  2018-04-21       Impact factor: 5.118

8.  De Novo Transcriptome Sequencing of the Deep-Sea-Derived Fungus Dichotomomyces cejpii and Analysis of Gliotoxin Biosynthesis Genes.

Authors:  Wei Ye; Weimin Zhang; Taomei Liu; Zilei Huang; Muzi Zhu; Yuchan Chen; Haohua Li; Saini Li
Journal:  Int J Mol Sci       Date:  2018-06-29       Impact factor: 5.923

9.  Efficient biosynthesis of heterodimeric C3-aryl pyrroloindoline alkaloids.

Authors:  Wenya Tian; Chenghai Sun; Mei Zheng; Jeffrey R Harmer; Mingjia Yu; Yanan Zhang; Haidong Peng; Dongqing Zhu; Zixin Deng; Shi-Lu Chen; Mehdi Mobli; Xinying Jia; Xudong Qu
Journal:  Nat Commun       Date:  2018-10-24       Impact factor: 14.919

10.  Isolation, Structural Characterization and Antidiabetic Activity of New Diketopiperazine Alkaloids from Mangrove Endophytic Fungus Aspergillus sp. 16-5c.

Authors:  Geting Ye; Cuiying Huang; Jialin Li; Tao Chen; Jing Tang; Wenbin Liu; Yuhua Long
Journal:  Mar Drugs       Date:  2021-07-20       Impact factor: 5.118
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