| Literature DB >> 27533006 |
Abstract
The innate response to many pathogens involves type I interferon production that is initiated upon cytosolic detection of double-stranded DNA (dsDNA), but how dsDNA is detected is controversial. In this issue of Immunity, Gray et al. (2016) use genetics to bring some much-needed clarity to the field.Mesh:
Substances:
Year: 2016 PMID: 27533006 DOI: 10.1016/j.immuni.2016.08.006
Source DB: PubMed Journal: Immunity ISSN: 1074-7613 Impact factor: 31.745