Literature DB >> 2751290

Efficacy of ciprofloxacin against Leptospira interrogans serogroup icterohaemorrhagiae.

I Shalit1, A Barnea, A Shahar.   

Abstract

Ciprofloxacin activity against Leptospira interrogans serogroup icterohaemorrhagiae was studied in vitro and in an animal model. The MBC of ciprofloxacin was 0.6 microgram/ml. Three of three Syrian hamsters died 8 to 9 days after intraperitoneal challenge with 10(6) leptospires. In contrast, five of six animals given ciprofloxacin 3 or 5 days after challenge survived.

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Year:  1989        PMID: 2751290      PMCID: PMC172537          DOI: 10.1128/AAC.33.5.788

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN: 0066-4804            Impact factor:   5.191


  3 in total

1.  In vitro susceptibilities of five Leptospira strains to 16 antimicrobial agents.

Authors:  S Oie; K Hironaga; A Koshiro; H Konishi; Z Yoshii
Journal:  Antimicrob Agents Chemother       Date:  1983-12       Impact factor: 5.191

Review 2.  Human leptospirosis.

Authors:  R D Feigin; D C Anderson
Journal:  CRC Crit Rev Clin Lab Sci       Date:  1975-03

3.  Penicillins, cephalosporins, and tetracyclines in treatment of hamsters with fatal leptospirosis.

Authors:  A D Alexander; P L Rule
Journal:  Antimicrob Agents Chemother       Date:  1986-12       Impact factor: 5.191

  3 in total
  10 in total

1.  In vitro susceptibilities of seven Leptospira species to traditional and newer antibiotics.

Authors:  Duane R Hospenthal; Clinton K Murray
Journal:  Antimicrob Agents Chemother       Date:  2003-08       Impact factor: 5.191

2.  Efficacy of macrolides and telithromycin against leptospirosis in a hamster model.

Authors:  James E Moon; Michael W Ellis; Michael C Ellis; Matthew E Griffith; Joshua S Hawley; Robert G Rivard; Suzanne McCall; Duane R Hospenthal; Clinton K Murray
Journal:  Antimicrob Agents Chemother       Date:  2006-06       Impact factor: 5.191

3.  Efficacy of fluoroquinolones against Leptospira interrogans in a hamster model.

Authors:  Matthew E Griffith; James E Moon; Erica N Johnson; Kyra P Clark; Joshua S Hawley; Duane R Hospenthal; Clinton K Murray
Journal:  Antimicrob Agents Chemother       Date:  2007-04-30       Impact factor: 5.191

4.  Detection of leptospires in urine by PCR for early diagnosis of leptospirosis.

Authors:  A E Bal; C Gravekamp; R A Hartskeerl; J De Meza-Brewster; H Korver; W J Terpstra
Journal:  J Clin Microbiol       Date:  1994-08       Impact factor: 5.948

5.  Quantitative PCR assay to evaluate ampicillin, ofloxacin, and doxycycline for treatment of experimental leptospirosis.

Authors:  Johann Truccolo; Françoise Charavay; Fabrice Merien; Philippe Perolat
Journal:  Antimicrob Agents Chemother       Date:  2002-03       Impact factor: 5.191

6.  Determination of susceptibilities of 26 Leptospira sp. serovars to 24 antimicrobial agents by a broth microdilution technique.

Authors:  Clinton K Murray; Duane R Hospenthal
Journal:  Antimicrob Agents Chemother       Date:  2004-10       Impact factor: 5.191

7.  Broth microdilution susceptibility testing for Leptospira spp.

Authors:  Clinton K Murray; Duane R Hospenthal
Journal:  Antimicrob Agents Chemother       Date:  2004-05       Impact factor: 5.191

8.  Antimicrobial effects of a new carboxyquinolone drug, Q-35, on five serogroups of Leptospira interrogans.

Authors:  I Takashima; M Ngoma; N Hashimoto
Journal:  Antimicrob Agents Chemother       Date:  1993-04       Impact factor: 5.191

Review 9.  Newly documented antimicrobial activity of quinolones.

Authors:  Y X Furet; J C Pechère
Journal:  Eur J Clin Microbiol Infect Dis       Date:  1991-04       Impact factor: 3.267

10.  Proteome-wide cellular protein concentrations of the human pathogen Leptospira interrogans.

Authors:  Johan Malmström; Martin Beck; Alexander Schmidt; Vinzenz Lange; Eric W Deutsch; Ruedi Aebersold
Journal:  Nature       Date:  2009-07-15       Impact factor: 49.962

  10 in total

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