| Literature DB >> 2751290 |
I Shalit1, A Barnea, A Shahar.
Abstract
Ciprofloxacin activity against Leptospira interrogans serogroup icterohaemorrhagiae was studied in vitro and in an animal model. The MBC of ciprofloxacin was 0.6 microgram/ml. Three of three Syrian hamsters died 8 to 9 days after intraperitoneal challenge with 10(6) leptospires. In contrast, five of six animals given ciprofloxacin 3 or 5 days after challenge survived.Entities:
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Year: 1989 PMID: 2751290 PMCID: PMC172537 DOI: 10.1128/AAC.33.5.788
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191