Literature DB >> 15388465

Determination of susceptibilities of 26 Leptospira sp. serovars to 24 antimicrobial agents by a broth microdilution technique.

Clinton K Murray1, Duane R Hospenthal.   

Abstract

The MICs of 24 antimicrobials for 26 Leptospira spp. serovars were determined using a broth microdilution technique. The MICs at which 90% of isolates tested were inhibited (MIC(90)s) of cefepime, imipenem-cilastatin, erythromycin, clarithromycin, and telithromycin were all </=0.01 microg/ml. The MIC(90)s of amoxicillin, aztreonam, cefdinir, chloramphenicol, and penicillin G were >/=3.13 microg/ml. Many antimicrobials have excellent in vitro activity against Leptospira.

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Year:  2004        PMID： 15388465      PMCID： PMC521904          DOI： 10.1128/AAC.48.10.4002-4005.2004

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  16 in total

1.  Preliminary evaluation of antimicrobial agents for treatment of Leptospira interrogans serovar pomona infection in hamsters and swine.

Authors:  D P Alt; C A Bolin
Journal:  Am J Vet Res       Date:  1996-01       Impact factor: 1.156

2.  Cephalothin in the treatment of experimental leptospirosis in hamsters.

Authors:  R N Yoshimori; H S Goldberg; D C Blenden
Journal:  Antimicrob Agents Chemother (Bethesda)       Date:  1965

3.  The susceptibility of a strain of Leptospira interrogans serogroup icterohaemorrhagiae to amoxycillin, erythromycin, lincomycin, tetracycline, oxytetracycline and minocycline.

Authors:  E S Broughton; L E Flack
Journal:  Zentralbl Bakteriol Mikrobiol Hyg A       Date:  1986-07

4.  Broth microdilution susceptibility testing for Leptospira spp.

Authors:  Clinton K Murray; Duane R Hospenthal
Journal:  Antimicrob Agents Chemother       Date:  2004-05       Impact factor: 5.191

5.  Penicillin therapy in icteric leptospirosis.

Authors:  C N Edwards; G D Nicholson; T A Hassell; C O Everard; J Callender
Journal:  Am J Trop Med Hyg       Date:  1988-10       Impact factor: 2.345

6.  Penicillins, cephalosporins, and tetracyclines in treatment of hamsters with fatal leptospirosis.

Authors:  A D Alexander; P L Rule
Journal:  Antimicrob Agents Chemother       Date:  1986-12       Impact factor: 5.191

7.  Antimicrobial effects of a new carboxyquinolone drug, Q-35, on five serogroups of Leptospira interrogans.

Authors:  I Takashima; M Ngoma; N Hashimoto
Journal:  Antimicrob Agents Chemother       Date:  1993-04       Impact factor: 5.191

8.  Efficacy of ciprofloxacin against Leptospira interrogans serogroup icterohaemorrhagiae.

Authors:  I Shalit; A Barnea; A Shahar
Journal:  Antimicrob Agents Chemother       Date:  1989-05       Impact factor: 5.191

9.  Placebo-controlled trial of intravenous penicillin for severe and late leptospirosis.

Authors:  G Watt; L P Padre; M L Tuazon; C Calubaquib; E Santiago; C P Ranoa; L W Laughlin
Journal:  Lancet       Date:  1988-02-27       Impact factor: 79.321

10.  Ceftriaxone compared with sodium penicillin g for treatment of severe leptospirosis.

Authors:  Thanachai Panaphut; Somnuek Domrongkitchaiporn; Asda Vibhagool; Bandit Thinkamrop; Wattanachai Susaengrat
Journal:  Clin Infect Dis       Date:  2003-06-06       Impact factor: 9.079
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  17 in total

1.  In vitro and in vivo activity of first generation cephalosporins against Leptospira.

Authors:  Brande M Harris; Peter J Blatz; Mary K Hinkle; Suzanne McCall; Miriam L Beckius; Katrin Mende; Janelle L Robertson; Matthew E Griffith; Clinton K Murray; Duane R Hospenthal
Journal:  Am J Trop Med Hyg       Date:  2011-11       Impact factor: 2.345

2.  In vitro sensitivity and resistance of 46 Leptospira strains isolated from rats in the Philippines to 14 antimicrobial agents.

Authors:  Antara Chakraborty; Satoshi Miyahara; Sharon Y A M Villanueva; Nina G Gloriani; Shin-Ichi Yoshida
Journal:  Antimicrob Agents Chemother       Date:  2010-09-20       Impact factor: 5.191

3.  Efficacy of macrolides and telithromycin against leptospirosis in a hamster model.

Authors:  James E Moon; Michael W Ellis; Michael C Ellis; Matthew E Griffith; Joshua S Hawley; Robert G Rivard; Suzanne McCall; Duane R Hospenthal; Clinton K Murray
Journal:  Antimicrob Agents Chemother       Date:  2006-06       Impact factor: 5.191

4.  Efficacy of fluoroquinolones against Leptospira interrogans in a hamster model.

Authors:  Matthew E Griffith; James E Moon; Erica N Johnson; Kyra P Clark; Joshua S Hawley; Duane R Hospenthal; Clinton K Murray
Journal:  Antimicrob Agents Chemother       Date:  2007-04-30       Impact factor: 5.191

5.  Antimicrobial susceptibilities of geographically diverse clinical human isolates of Leptospira.

Authors:  Roseanne A Ressner; Matthew E Griffith; Miriam L Beckius; Guillermo Pimentel; R Scott Miller; Katrin Mende; Susan L Fraser; Renee L Galloway; Duane R Hospenthal; Clinton K Murray
Journal:  Antimicrob Agents Chemother       Date:  2008-04-14       Impact factor: 5.191

6.  Use of luminescent Leptospira interrogans for enumeration in biological assays.

Authors:  Gerald L Murray; Amy M King; Amporn Srikram; Rasana W Sermswan; Ben Adler
Journal:  J Clin Microbiol       Date:  2010-04-07       Impact factor: 5.948

7.  Antibiotic Efficacy in Eliminating Leptospiruria in California Sea Lions (Zalophus californianus) Stranding with Leptospirosis.

Authors:  K C Prager; David P Alt; Michael G Buhnerkempe; Denise J Greig; Renee L Galloway; Qingzhong Wu; Frances M D Gulland; James O Lloyd-Smith
Journal:  Aquat Mamm       Date:  2015-05-26       Impact factor: 1.382

8.  Leptospirosis in the tropics and in travelers.

Authors:  Jessica N Ricaldi; Joseph M Vinetz
Journal:  Curr Infect Dis Rep       Date:  2006-01       Impact factor: 3.725

9.  Rapid isolation and susceptibility testing of Leptospira spp. using a new solid medium, LVW agar.

Authors:  Vanaporn Wuthiekanun; Premjit Amornchai; Daniel H Paris; Sayan Langla; Janjira Thaipadunpanit; Wirongrong Chierakul; Lee D Smythe; Nicholas J White; Nicholas P J Day; Direk Limmathurotsakul; Sharon J Peacock
Journal:  Antimicrob Agents Chemother       Date:  2012-10-31       Impact factor: 5.191

10.  Antimicrobial Disk Susceptibility Testing of Leptospira spp. Using Leptospira Vanaporn Wuthiekanun (LVW) Agar.

Authors:  Vanaporn Wuthiekanun; Premjit Amornchai; Sayan Langla; Nicholas J White; Nicholas P J Day; Direk Limmathurotsakul; Sharon J Peacock
Journal:  Am J Trop Med Hyg       Date:  2015-06-08       Impact factor: 2.345
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