Literature DB >> 27503959

Using Genetic Technologies To Reduce, Rather Than Widen, Health Disparities.

Caren E Smith1, Stephanie M Fullerton2, Keith A Dookeran3, Heather Hampel4, Adrienne Tin5, Nisa M Maruthur6, Jonathan C Schisler7, Jeffrey A Henderson8, Katherine L Tucker9, José M Ordovás10.   

Abstract

Evidence shows that both biological and nonbiological factors contribute to health disparities. Genetics, in particular, plays a part in how common diseases manifest themselves. Today, unprecedented advances in genetically based diagnoses and treatments provide opportunities for personalized medicine. However, disadvantaged groups may lack access to these advances, and treatments based on research on non-Hispanic whites might not be generalizable to members of minority groups. Unless genetic technologies become universally accessible, existing disparities could be widened. Addressing this issue will require integrated strategies, including expanding genetic research, improving genetic literacy, and enhancing access to genetic technologies among minority populations in a way that avoids harms such as stigmatization. Project HOPE—The People-to-People Health Foundation, Inc.

Entities:  

Keywords:  Determinants Of Health; Disparities; Minority Health; Public Health; Research And Technology

Mesh:

Year:  2016        PMID: 27503959      PMCID: PMC5100696          DOI: 10.1377/hlthaff.2015.1476

Source DB:  PubMed          Journal:  Health Aff (Millwood)        ISSN: 0278-2715            Impact factor:   6.301


  46 in total

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Authors:  Susan M Domchek; Tara M Friebel; Christian F Singer; D Gareth Evans; Henry T Lynch; Claudine Isaacs; Judy E Garber; Susan L Neuhausen; Ellen Matloff; Rosalind Eeles; Gabriella Pichert; Laura Van t'veer; Nadine Tung; Jeffrey N Weitzel; Fergus J Couch; Wendy S Rubinstein; Patricia A Ganz; Mary B Daly; Olufunmilayo I Olopade; Gail Tomlinson; Joellen Schildkraut; Joanne L Blum; Timothy R Rebbeck
Journal:  JAMA       Date:  2010-09-01       Impact factor: 56.272

2.  Rural Mexican-Americans' perceptions of family health history, genetics, and disease risk: implications for disparities-focused research dissemination.

Authors:  Rachel Malen; Sarah Knerr; Fernanda Delgado; Stephanie M Fullerton; Beti Thompson
Journal:  J Community Genet       Date:  2015-07-04

3.  Natural and sexual selection in a monogamous historical human population.

Authors:  Alexandre Courtiol; Jenni E Pettay; Markus Jokela; Anna Rotkirch; Virpi Lummaa
Journal:  Proc Natl Acad Sci U S A       Date:  2012-04-30       Impact factor: 11.205

4.  Racial variation in breast tumor promoter methylation in the Carolina Breast Cancer Study.

Authors:  Kathleen Conway; Sharon N Edmiston; Chiu-Kit Tse; Christopher Bryant; Pei Fen Kuan; Brionna Y Hair; Eloise A Parrish; Ryan May; Theresa Swift-Scanlan
Journal:  Cancer Epidemiol Biomarkers Prev       Date:  2015-03-25       Impact factor: 4.254

5.  Hemostatic Factors, APOL1 Risk Variants, and the Risk of ESRD in the Atherosclerosis Risk in Communities Study.

Authors:  Adrienne Tin; Morgan E Grams; Nisa M Maruthur; Brad C Astor; David Couper; Thomas H Mosley; Myriam Fornage; Rulan S Parekh; Josef Coresh; Wen Hong Linda Kao
Journal:  Clin J Am Soc Nephrol       Date:  2015-04-17       Impact factor: 8.237

6.  Breast cancer subtypes as defined by the estrogen receptor (ER), progesterone receptor (PR), and the human epidermal growth factor receptor 2 (HER2) among women with invasive breast cancer in California, 1999-2004.

Authors:  Carol A Parise; Katrina R Bauer; Monica M Brown; Vincent Caggiano
Journal:  Breast J       Date:  2009-09-17       Impact factor: 2.431

7.  Determining the effects and challenges of incorporating genetic testing into primary care management of hypertensive patients with African ancestry.

Authors:  C R Horowitz; N S Abul-Husn; S Ellis; M A Ramos; R Negron; M Suprun; R E Zinberg; T Sabin; D Hauser; N Calman; E Bagiella; E P Bottinger
Journal:  Contemp Clin Trials       Date:  2015-12-30       Impact factor: 2.226

8.  Cancer statistics for Hispanics/Latinos, 2012.

Authors:  Rebecca Siegel; Deepa Naishadham; Ahmedin Jemal
Journal:  CA Cancer J Clin       Date:  2012 Sep-Oct       Impact factor: 508.702

9.  Disparities in BRCA testing: when insurance coverage is not a barrier.

Authors:  Windy Olaya; Pamela Esquivel; Jan H Wong; John W Morgan; Adam Freeberg; Sharmila Roy-Chowdhury; Sharon S Lum
Journal:  Am J Surg       Date:  2009-10       Impact factor: 2.565

10.  APOL1 genetic variants, chronic kidney diseases and hypertension in mixed ancestry South Africans.

Authors:  Tandi E Matsha; Andre P Kengne; Katya L Masconi; Yandiswa Y Yako; Rajiv T Erasmus
Journal:  BMC Genet       Date:  2015-06-26       Impact factor: 2.797

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  23 in total

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Authors:  Kelly E Ormond; Douglas P Mortlock; Derek T Scholes; Yvonne Bombard; Lawrence C Brody; W Andrew Faucett; Nanibaa' A Garrison; Laura Hercher; Rosario Isasi; Anna Middleton; Kiran Musunuru; Daniel Shriner; Alice Virani; Caroline E Young
Journal:  Am J Hum Genet       Date:  2017-08-03       Impact factor: 11.025

2.  Application of the ConNECT Framework to Precision Health and Health Disparities.

Authors:  Usha Menon; Kimlin Ashing; Mei Wei Chang; Shannon M Christy; Katarina Friberg-Felsted; Virginia Gil Rivas; Clement K Gwede; Qian Lu; Cathy D Meade; Jamila Sly; Monica Wang; Betina Yanez; Karen Yeary; Jean C Yi; Kassandra I Alcaraz
Journal:  Nurs Res       Date:  2019 Mar/Apr       Impact factor: 2.381

Review 3.  The Role of Safety-Net Hospitals in Reducing Disparities in Breast Cancer Care.

Authors:  Angelena Crown; Kalpana Ramiah; Bruce Siegel; Kathie-Ann Joseph
Journal:  Ann Surg Oncol       Date:  2022-03-31       Impact factor: 5.344

4.  A Framework for Promoting Diversity, Equity, and Inclusion in Genetics and Genomics Research.

Authors:  Timothy R Rebbeck; John F P Bridges; Jennifer W Mack; Stacy W Gray; Jeffrey M Trent; Suzanne George; Norah L Crossnohere; Electra D Paskett; Corrie A Painter; Nikhil Wagle; Miria Kano; Patricia Nez Henderson; Jeffrey A Henderson; Shiraz I Mishra; Cheryl L Willman; Andrew L Sussman
Journal:  JAMA Health Forum       Date:  2022-04-15

5.  Racial and ethnic differences in knowledge and attitudes about genetic testing in the US: Systematic review.

Authors:  Juan R Canedo; Stephania T Miller; Hector F Myers; Maureen Sanderson
Journal:  J Genet Couns       Date:  2019-01-21       Impact factor: 2.537

6.  Development and early implementation of an Accessible, Relational, Inclusive and Actionable approach to genetic counseling: The ARIA model.

Authors:  Leslie Riddle; Laura M Amendola; Marian J Gilmore; Claudia Guerra; Barbara Biesecker; Tia L Kauffman; Katherine Anderson; Alan F Rope; Michael C Leo; Mikaella Caruncho; Gail P Jarvik; Benjamin Wilfond; Katrina A B Goddard; Galen Joseph
Journal:  Patient Educ Couns       Date:  2020-12-23

Review 7.  Future of Rare Diseases Research 2017-2027: An IRDiRC Perspective.

Authors:  Christopher P Austin; Christine M Cutillo; Lilian P L Lau; Anneliene H Jonker; Ana Rath; Daria Julkowska; David Thomson; Sharon F Terry; Béatrice de Montleau; Diego Ardigò; Virginie Hivert; Kym M Boycott; Gareth Baynam; Petra Kaufmann; Domenica Taruscio; Hanns Lochmüller; Makoto Suematsu; Carlo Incerti; Ruxandra Draghia-Akli; Irene Norstedt; Lu Wang; Hugh J S Dawkins
Journal:  Clin Transl Sci       Date:  2017-10-23       Impact factor: 4.689

Review 8.  A framework for enhancing ethical genomic research with Indigenous communities.

Authors:  Katrina G Claw; Matthew Z Anderson; Rene L Begay; Krystal S Tsosie; Keolu Fox; Nanibaa' A Garrison
Journal:  Nat Commun       Date:  2018-07-27       Impact factor: 14.919

9.  State of recent literature on communication about cancer genetic testing among Latinx populations.

Authors:  Daniel Chavez-Yenter; Wen-Ying Sylvia Chou; Kimberly A Kaphingst
Journal:  J Genet Couns       Date:  2020-11-03       Impact factor: 2.717

10.  Factors influencing precision medicine knowledge and attitudes.

Authors:  Rohini Chakravarthy; Sarah C Stallings; Michael Williams; Megan Hollister; Mario Davidson; Juan Canedo; Consuelo H Wilkins
Journal:  PLoS One       Date:  2020-11-11       Impact factor: 3.752

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