Literature DB >> 27491350

Ever HRD a ubiquitin-gated channel?

Ting Zhang1, Yihong Ye1.   

Abstract

Elimination of misfolded proteins of the endoplasmic reticulum (ER) requires their retrotranslocation from the ER to the cytosol via membrane-bound ubiquitin ligase complexes. Baldridge and Rapoport now reconstitute a key step of retrotranslocation, demonstrating a protein conduit gated by ubiquitination.

Mesh：

Substances：

Year:  2016        PMID： 27491350      PMCID： PMC5113310          DOI： 10.1038/cr.2016.92

Source DB:  PubMed          Journal:  Cell Res        ISSN： 1001-0602            Impact factor:   25.617


  10 in total

1.  RING fingers mediate ubiquitin-conjugating enzyme (E2)-dependent ubiquitination.

Authors:  K L Lorick; J P Jensen; S Fang; A M Ong; S Hatakeyama; A M Weissman
Journal:  Proc Natl Acad Sci U S A       Date:  1999-09-28       Impact factor: 11.205

Review 2.  Protein translocation by the Sec61/SecY channel.

Authors:  Andrew R Osborne; Tom A Rapoport; Bert van den Berg
Journal:  Annu Rev Cell Dev Biol       Date:  2005       Impact factor: 13.827

3.  Distinct ubiquitin-ligase complexes define convergent pathways for the degradation of ER proteins.

Authors:  Pedro Carvalho; Veit Goder; Tom A Rapoport
Journal:  Cell       Date:  2006-07-28       Impact factor: 41.582

Review 4.  The increasing complexity of the ubiquitin code.

Authors:  Richard Yau; Michael Rape
Journal:  Nat Cell Biol       Date:  2016-05-27       Impact factor: 28.824

Review 5.  Roles of p97-associated deubiquitinases in protein quality control at the endoplasmic reticulum.

Authors:  Yanfen Liu; Yihong Ye
Journal:  Curr Protein Pept Sci       Date:  2012-08       Impact factor: 3.272

6.  Retrotranslocation of a misfolded luminal ER protein by the ubiquitin-ligase Hrd1p.

Authors:  Pedro Carvalho; Ann Marie Stanley; Tom A Rapoport
Journal:  Cell       Date:  2010-11-12       Impact factor: 41.582

7.  Autoubiquitination of the Hrd1 Ligase Triggers Protein Retrotranslocation in ERAD.

Authors:  Ryan D Baldridge; Tom A Rapoport
Journal:  Cell       Date:  2016-06-16       Impact factor: 41.582

8.  Key steps in ERAD of luminal ER proteins reconstituted with purified components.

Authors:  Alexander Stein; Annamaria Ruggiano; Pedro Carvalho; Tom A Rapoport
Journal:  Cell       Date:  2014-09-11       Impact factor: 41.582

Review 9.  Cleaning up in the endoplasmic reticulum: ubiquitin in charge.

Authors:  John C Christianson; Yihong Ye
Journal:  Nat Struct Mol Biol       Date:  2014-04       Impact factor: 18.361

10.  Misfolded proteins are sorted by a sequential checkpoint mechanism of ER quality control.

Authors:  Shilpa Vashist; Davis T W Ng
Journal:  J Cell Biol       Date:  2004-04       Impact factor: 10.539
  10 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.