Literature DB >> 27488743

Regulation of Gastrointestinal Smooth Muscle Function by Interstitial Cells.

Kenton M Sanders1, Yoshihiko Kito2, Sung Jin Hwang3, Sean M Ward3.   

Abstract

Interstitial cells of mesenchymal origin form gap junctions with smooth muscle cells in visceral smooth muscles and provide important regulatory functions. In gastrointestinal (GI) muscles, there are two distinct classes of interstitial cells, c-Kit(+) interstitial cells of Cajal and PDGFRα(+) cells, that regulate motility patterns. Loss of these cells may contribute to symptoms in GI motility disorders. ©2016 Int. Union Physiol. Sci./Am. Physiol. Soc.

Entities:  

Mesh：

Year:  2016        PMID： 27488743      PMCID： PMC5504460          DOI： 10.1152/physiol.00006.2016

Source DB:  PubMed          Journal:  Physiology (Bethesda)        ISSN： 1548-9221


  126 in total

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