Literature DB >> 2747261

Use of extracts of Picralima nitida bark in the treatment of experimental trypanosomiasis: a preliminary study.

L O Wosu1, C C Ibe.   

Abstract

The effect of a boiling water extract of Picralima nitida bark against trypanosomes (T. brucei) in rats was compared with that of diminazene aceturate at 8 mg/kg i.p. Results showed that the extract had a definite trypanocidal effect which was statistically comparable to that of diminazene aceturate. Further work is needed to identify the active pharmacological agent and to standardise the usage of the agent in practice.

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Year:  1989        PMID： 2747261     DOI： 10.1016/0378-8741(89)90032-9

Source DB:  PubMed          Journal:  J Ethnopharmacol        ISSN： 0378-8741            Impact factor:   4.360


  5 in total

1.  Evaluation of three medicinal plant extracts against Plasmodium falciparum and selected microganisms.

Authors:  Abiodun Falodun; Vincent Imieje; Osayewenre Erharuyi; Joy Ahomafor; Melissa R Jacob; Shabana I Khan; Mark T Hamann
Journal:  Afr J Tradit Complement Altern Med       Date:  2014-06-04

2.  Evaluation of antitrypanosomal and anti inflammatory activities of selected Nigerian medicinal plants in mice.

Authors:  Victoria O Adelodun; C A Elusiyan; F O Olorunmola; F B Adewoyin; N O Omisore; A O Adepiti; J M Agbedahunsi; C O Adewunmi
Journal:  Afr J Tradit Complement Altern Med       Date:  2013-10-03

3.  The anti-shigellosis activity of the methanol extract of Picralima nitida on Shigella dysenteriae type I induced diarrhoea in rats.

Authors:  Laure Brigitte Mabeku Kouitcheu; Joseph Lebel Tamesse; Jacques Kouam
Journal:  BMC Complement Altern Med       Date:  2013-08-17       Impact factor: 3.659

4.  The alkaloid alstonine: a review of its pharmacological properties.

Authors:  E Elisabetsky; L Costa-Campos
Journal:  Evid Based Complement Alternat Med       Date:  2006-01-16       Impact factor: 2.629

5.  Pro-apoptotic and anti-adhesive effects of four African plant extracts on the breast cancer cell line MCF-7.

Authors:  Nadja Engel; Abiodun Falodun; Juliane Kühn; Udo Kragl; Peter Langer; Barbara Nebe
Journal:  BMC Complement Altern Med       Date:  2014-09-09       Impact factor: 3.659
  5 in total

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