Literature DB >> 27462382

Simple microfluidic stagnation point flow geometries.

Greet Dockx1, Tom Verwijlen1, Wouter Sempels2, Mathias Nagel3, Paula Moldenaers1, Johan Hofkens2, Jan Vermant3.   

Abstract

A geometrically simple flow cell is proposed to generate different types of stagnation flows, using a separation flow and small variations of the geometric parameters. Flows with high local deformation rates can be changed from purely rotational, over simple shear flow, to extensional flow in a region surrounding a stagnation point. Computational fluid dynamic calculations are used to analyse how variations of the geometrical parameters affect the flow field. These numerical calculations are compared to the experimentally obtained streamlines of different designs, which have been determined by high speed confocal microscopy. As the flow type is dictated predominantly by the geometrical parameters, such simple separating flow devices may alleviate the requirements for flow control, while offering good stability for a wide variety of flow types.

Year:  2016        PMID: 27462382      PMCID: PMC4920808          DOI: 10.1063/1.4954936

Source DB:  PubMed          Journal:  Biomicrofluidics        ISSN: 1932-1058            Impact factor:   2.800


  15 in total

1.  Hydrodynamic shearing of DNA in a polymeric microfluidic device.

Authors:  Irina V Nesterova; Mateusz L Hupert; Malgorzata A Witek; Steven A Soper
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2.  Shear-stress sensitive lenticular vesicles for targeted drug delivery.

Authors:  Margaret N Holme; Illya A Fedotenko; Daniel Abegg; Jasmin Althaus; Lucille Babel; France Favarger; Renate Reiter; Radu Tanasescu; Pierre-Léonard Zaffalon; André Ziegler; Bert Müller; Till Saxer; Andreas Zumbuehl
Journal:  Nat Nanotechnol       Date:  2012-06-10       Impact factor: 39.213

Review 3.  Cells on chips.

Authors:  Jamil El-Ali; Peter K Sorger; Klavs F Jensen
Journal:  Nature       Date:  2006-07-27       Impact factor: 49.962

4.  Structure and dynamics of colloidal depletion gels: coincidence of transitions and heterogeneity.

Authors:  Clare J Dibble; Michael Kogan; Michael J Solomon
Journal:  Phys Rev E Stat Nonlin Soft Matter Phys       Date:  2006-10-20

5.  Dynamics and configurational fluctuations of single DNA molecules in linear mixed flows.

Authors:  Joe S Hur; Eric S G Shaqfeh; Hazen P Babcock; Steven Chu
Journal:  Phys Rev E Stat Nonlin Soft Matter Phys       Date:  2002-07-26

6.  Imaging the microscopic structure of shear thinning and thickening colloidal suspensions.

Authors:  Xiang Cheng; Jonathan H McCoy; Jacob N Israelachvili; Itai Cohen
Journal:  Science       Date:  2011-09-02       Impact factor: 47.728

7.  Extensional flow of hyaluronic acid solutions in an optimized microfluidic cross-slot device.

Authors:  S J Haward; A Jaishankar; M S N Oliveira; M A Alves; G H McKinley
Journal:  Biomicrofluidics       Date:  2013-07-30       Impact factor: 2.800

8.  Interstitial flow influences direction of tumor cell migration through competing mechanisms.

Authors:  William J Polacheck; Joseph L Charest; Roger D Kamm
Journal:  Proc Natl Acad Sci U S A       Date:  2011-06-20       Impact factor: 11.205

Review 9.  Poly(dimethylsiloxane) as a material for fabricating microfluidic devices.

Authors:  J Cooper McDonald; George M Whitesides
Journal:  Acc Chem Res       Date:  2002-07       Impact factor: 22.384

10.  Microfluidic systems for single DNA dynamics.

Authors:  Danielle J Mai; Christopher Brockman; Charles M Schroeder
Journal:  Soft Matter       Date:  2012-07-03       Impact factor: 3.679

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  1 in total

1.  Preface to Special Topic: Invited Articles on Microfluidic Rheology.

Authors:  Anke Lindner; Paulo E Arratia
Journal:  Biomicrofluidics       Date:  2016-08-26       Impact factor: 2.800

  1 in total

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