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Literature DB >> 27460761

Versicones E-H and arugosin K produced by the mangrove-derived fungus Aspergillus versicolor HDN11-84.

Feng Li¹, Wenqiang Guo¹, Qian Che¹, Tianjiao Zhu¹, Qianqun Gu¹, Dehai Li¹.

Abstract

Four new xanthonoids, versicones E-H (1-4), and a biogenetically related new derivative arugosin K (5), were isolated from a culture extract of the mangrove-derived fungus Aspergillus versicolor HDN11-84. Their structures were elucidated on the basis of extensive NMR spectroscopic data analysis. Versicone E (1) represents the first example of naturally occurring xanthonoids containing a 2-butenamide moiety. Among them, 5 showed the best cytotoxicity against Hela cell line with an IC50 value of 9.2 μm.

Entities: Chemical Disease Species

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Year: 2016 PMID： 27460761 DOI： 10.1038/ja.2016.95

Source DB: PubMed Journal: J Antibiot (Tokyo) ISSN： 0021-8820 Impact factor: 2.649

16 in total

Review 1. Naturally-occurring xanthones: recent developments.

Authors: L M M Vieira; A Kijjoa
Journal: Curr Med Chem Date: 2005 Impact factor: 4.530

Review 2. Xanthones from fungi, lichens, and bacteria: the natural products and their synthesis.

Authors: Kye-Simeon Masters; Stefan Bräse
Journal: Chem Rev Date: 2012-05-22 Impact factor: 60.622

Review 3. Recent insights into the biosynthesis and biological activities of natural xanthones.

Authors: H R El-Seedi; M A El-Barbary; D M H El-Ghorab; L Bohlin; Anna-Karin Borg-Karlson; U Göransson; R Verpoorte
Journal: Curr Med Chem Date: 2010 Impact factor: 4.530

4. Unprecedented citrinin trimer tricitinol B functions as a novel topoisomerase IIα inhibitor.

Authors: Lin Du; Hong-Chun Liu; Wei Fu; De-Hai Li; Qiu-Ming Pan; Tian-Jiao Zhu; Mei-Yu Geng; Qian-Qun Gu
Journal: J Med Chem Date: 2011-07-28 Impact factor: 7.446

5. Aspergiolides C and D: spirocyclic aromatic polyketides with potent protein kinase c-Met inhibitory effects.

Authors: Lin Du; Jing Ai; Dehai Li; Tianjiao Zhu; Ying Wang; Michael Knauer; Torsten Bruhn; Hongbing Liu; Meiyu Geng; Qianqun Gu; Gerhard Bringmann
Journal: Chemistry Date: 2010-12-03 Impact factor: 5.236

6. The biosynthesis of fungal metabolites. Part V. Structure of variecoxanthones A, B, and C, metabolites of Aspergillus variecolor; conversion of variecoxanthone a into (plus or minus)-de-c-prenylepishamixanthone.

Authors: K K Chexal; J S Holker; T J Simpson; K Young
Journal: J Chem Soc Perkin 1 Date: 1975

7. New colorimetric cytotoxicity assay for anticancer-drug screening.

Authors: P Skehan; R Storeng; D Scudiero; A Monks; J McMahon; D Vistica; J T Warren; H Bokesch; S Kenney; M R Boyd
Journal: J Natl Cancer Inst Date: 1990-07-04 Impact factor: 13.506

8. New insights into the biosynthesis of prenylated xanthones: Xptb from Aspergillus nidulans catalyses an O-prenylation of xanthones.

Authors: Daniel Pockrandt; Lena Ludwig; Aili Fan; Gabriele M König; Shu-Ming Li
Journal: Chembiochem Date: 2012-11-13 Impact factor: 3.164

9. Antifungal New Oxepine-Containing Alkaloids and Xanthones from the Deep-Sea-Derived Fungus Aspergillus versicolor SCSIO 05879.

Authors: Junfeng Wang; Weijun He; Xiaolong Huang; Xinpeng Tian; Shengrong Liao; Bin Yang; Fazuo Wang; Xiaojiang Zhou; Yonghong Liu
Journal: J Agric Food Chem Date: 2016-03-30 Impact factor: 5.279