Literature DB >> 20156171

Recent insights into the biosynthesis and biological activities of natural xanthones.

H R El-Seedi1, M A El-Barbary, D M H El-Ghorab, L Bohlin, Anna-Karin Borg-Karlson, U Göransson, R Verpoorte.   

Abstract

This review focuses on recent advances in our understanding of the complex biosynthetic pathways and diverse biological activities of naturally occurring xanthones. The biosynthesis section covers studies published from 1989 to 2008 on xanthone production in plants and fungi, while the bioactivity review presents tabulated activities of more than 250 xanthones described in studies published from 2001 to 2008, together with structural information and indications of their wide-ranging potential uses as pharmacological tools. A large number of relevant papers have been published on these subjects (128 cited here), illustrating the diversity of the xanthones and their possible uses.

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Year:  2010        PMID: 20156171     DOI: 10.2174/092986710790712147

Source DB:  PubMed          Journal:  Curr Med Chem        ISSN: 0929-8673            Impact factor:   4.530


  15 in total

1.  2,3-Diarylxanthones as Potential Inhibitors of Arachidonic Acid Metabolic Pathways.

Authors:  Clementina M M Santos; Daniela Ribeiro; Artur M S Silva; Eduarda Fernandes
Journal:  Inflammation       Date:  2017-06       Impact factor: 4.092

2.  Genome-based deletion analysis reveals the prenyl xanthone biosynthesis pathway in Aspergillus nidulans.

Authors:  James F Sanchez; Ruth Entwistle; Jui-Hsiang Hung; Junko Yaegashi; Sofina Jain; Yi-Ming Chiang; Clay C C Wang; Berl R Oakley
Journal:  J Am Chem Soc       Date:  2011-02-25       Impact factor: 15.419

3.  Mangiferin, a natural xanthone, accelerates gastrointestinal transit in mice involving cholinergic mechanism.

Authors:  Talita Cavalcante Morais; Synara Cavalcante Lopes; Karine Maria Martins Bezerra Carvalho; Bruno Rodrigues Arruda; Francisco Thiago Correia de Souza; Maria Teresa Salles Trevisan; Vietla Satyanarayana Rao; Flávia Almeida Santos
Journal:  World J Gastroenterol       Date:  2012-07-07       Impact factor: 5.742

4.  Xanthones from roots, hairy roots and cell suspension cultures of selected Hypericum species and their antifungal activity against Candida albicans.

Authors:  Daniela Zubrická; Anna Mišianiková; Jana Henzelyová; Alessio Valletta; Giulia De Angelis; Felicia Diodata D'Auria; Giovanna Simonetti; Gabriella Pasqua; Eva Čellárová
Journal:  Plant Cell Rep       Date:  2015-07-21       Impact factor: 4.570

5.  Versicones E-H and arugosin K produced by the mangrove-derived fungus Aspergillus versicolor HDN11-84.

Authors:  Feng Li; Wenqiang Guo; Qian Che; Tianjiao Zhu; Qianqun Gu; Dehai Li
Journal:  J Antibiot (Tokyo)       Date:  2016-07-27       Impact factor: 2.649

Review 6.  Xanthone Biosynthetic Pathway in Plants: A Review.

Authors:  Juwairiah Remali; Idin Sahidin; Wan Mohd Aizat
Journal:  Front Plant Sci       Date:  2022-04-08       Impact factor: 6.627

Review 7.  Trypanocidal activity of marine natural products.

Authors:  Amy J Jones; Tanja Grkovic; Melissa L Sykes; Vicky M Avery
Journal:  Mar Drugs       Date:  2013-10-22       Impact factor: 5.118

8.  Heterocyclic analogues of xanthone and xanthione. 1H-pyrano[2,3-c:6,5-c]dipyrazol-4(7H)-ones and thiones: synthesis and NMR data.

Authors:  Barbara Datterl; Nicole Tröstner; Dorota Kucharski; Wolfgang Holzer
Journal:  Molecules       Date:  2010-09-01       Impact factor: 4.411

9.  Bifunctional CYP81AA proteins catalyse identical hydroxylations but alternative regioselective phenol couplings in plant xanthone biosynthesis.

Authors:  Islam El-Awaad; Marco Bocola; Till Beuerle; Benye Liu; Ludger Beerhues
Journal:  Nat Commun       Date:  2016-05-05       Impact factor: 14.919

10.  Delivery of Alpha-Mangostin Using Cyclodextrins through a Biological Membrane: Molecular Dynamics Simulation.

Authors:  Wiparat Hotarat; Bodee Nutho; Peter Wolschann; Thanyada Rungrotmongkol; Supot Hannongbua
Journal:  Molecules       Date:  2020-05-29       Impact factor: 4.411

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