Literature DB >> 27450499

PICSAR: Long Noncoding RNA in Cutaneous Squamous Cell Carcinoma.

Yunhai Luo1, Stefanie L Morgan1, Kevin C Wang2.   

Abstract

It is increasingly evident that long noncoding RNAs may play the roles of both oncogenes and tumor suppressors during cancer development. A new study from Piipponen et al. provides evidence that a long noncoding RNA, PICSAR, promotes cutaneous squamous cell carcinoma development through activation of extracellular signal-regulated kinase signaling. Because specific inhibition of PICSAR suppresses tumor growth, this long noncoding RNA may serve as a useful diagnostic marker and therapeutic target for cutaneous squamous cell carcinoma.
Copyright © 2016 The Authors. Published by Elsevier Inc. All rights reserved.

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Year:  2016        PMID： 27450499      PMCID： PMC6138452          DOI： 10.1016/j.jid.2016.04.013

Source DB:  PubMed          Journal:  J Invest Dermatol        ISSN： 0022-202X            Impact factor:   8.551


  10 in total

1.  Suppression of progenitor differentiation requires the long noncoding RNA ANCR.

Authors:  Markus Kretz; Dan E Webster; Ross J Flockhart; Carolyn S Lee; Ashley Zehnder; Vanessa Lopez-Pajares; Kun Qu; Grace X Y Zheng; Jennifer Chow; Grace E Kim; John L Rinn; Howard Y Chang; Zurab Siprashvili; Paul A Khavari
Journal:  Genes Dev       Date:  2012-02-02       Impact factor: 11.361

Review 2.  The emerging role of lncRNAs in cancer.

Authors:  Maite Huarte
Journal:  Nat Med       Date:  2015-11       Impact factor: 53.440

Review 3.  Molecular mechanisms of long noncoding RNAs.

Authors:  Kevin C Wang; Howard Y Chang
Journal:  Mol Cell       Date:  2011-09-16       Impact factor: 17.970

Review 4.  From keratinocyte to cancer: the pathogenesis and modeling of cutaneous squamous cell carcinoma.

Authors:  Vladimir Ratushny; Michael D Gober; Ryan Hick; Todd W Ridky; John T Seykora
Journal:  J Clin Invest       Date:  2012-02-01       Impact factor: 14.808

5.  Control of somatic tissue differentiation by the long non-coding RNA TINCR.

Authors:  Markus Kretz; Zurab Siprashvili; Ci Chu; Dan E Webster; Ashley Zehnder; Kun Qu; Carolyn S Lee; Ross J Flockhart; Abigail F Groff; Jennifer Chow; Danielle Johnston; Grace E Kim; Robert C Spitale; Ryan A Flynn; Grace X Y Zheng; Subhadra Aiyer; Arjun Raj; John L Rinn; Howard Y Chang; Paul A Khavari
Journal:  Nature       Date:  2012-12-02       Impact factor: 49.962

6.  IQGAP1 scaffold-kinase interaction blockade selectively targets RAS-MAP kinase-driven tumors.

Authors:  Katherine L Jameson; Pawel K Mazur; Ashley M Zehnder; Jiajing Zhang; Brian Zarnegar; Julien Sage; Paul A Khavari
Journal:  Nat Med       Date:  2013-04-21       Impact factor: 53.440

Review 7.  Consensus for Nonmelanoma Skin Cancer Treatment, Part II: Squamous Cell Carcinoma, Including a Cost Analysis of Treatment Methods.

Authors:  Arielle N B Kauvar; Christopher J Arpey; George Hruza; Suzanne M Olbricht; Richard Bennett; Bassel H Mahmoud
Journal:  Dermatol Surg       Date:  2015-11       Impact factor: 3.398

8.  Long Noncoding RNA PICSAR Promotes Growth of Cutaneous Squamous Cell Carcinoma by Regulating ERK1/2 Activity.

Authors:  Minna Piipponen; Liisa Nissinen; Mehdi Farshchian; Pilvi Riihilä; Atte Kivisaari; Markku Kallajoki; Juha Peltonen; Sirkku Peltonen; Veli-Matti Kähäri
Journal:  J Invest Dermatol       Date:  2016-04-02       Impact factor: 8.551

Review 9.  Long non-coding RNAs: new players in cell differentiation and development.

Authors:  Alessandro Fatica; Irene Bozzoni
Journal:  Nat Rev Genet       Date:  2013-12-03       Impact factor: 53.242

10.  Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis.

Authors:  Rajnish A Gupta; Nilay Shah; Kevin C Wang; Jeewon Kim; Hugo M Horlings; David J Wong; Miao-Chih Tsai; Tiffany Hung; Pedram Argani; John L Rinn; Yulei Wang; Pius Brzoska; Benjamin Kong; Rui Li; Robert B West; Marc J van de Vijver; Saraswati Sukumar; Howard Y Chang
Journal:  Nature       Date:  2010-04-15       Impact factor: 49.962
  10 in total
  4 in total

1.  A Prognostic 5-lncRNA Expression Signature for Head and Neck Squamous Cell Carcinoma.

Authors:  Guancheng Liu; Jinyang Zheng; Liming Zhuang; Yunxia Lv; Gangcai Zhu; Leiming Pi; Junchen Wang; Changhan Chen; Zhexuan Li; Jiangyi Liu; Liangjuan Chen; Gengming Cai; Xin Zhang
Journal:  Sci Rep       Date:  2018-10-15       Impact factor: 4.379

2.  Lnc-PICSAR contributes to cisplatin resistance by miR-485-5p/REV3L axis in cutaneous squamous cell carcinoma.

Authors:  Dan Wang; Xiaoqiang Zhou; Jing Yin; Yang Zhou
Journal:  Open Life Sci       Date:  2020-07-10       Impact factor: 0.938

3.  Long non-coding RNA PICSAR serves as a non-invasive biomarker for the diagnosis and prognosis of cutaneous squamous cell carcinoma.

Authors:  Jianping Lv; Wei Zhang; Yanhua Wang
Journal:  Clin Exp Med       Date:  2021-05-27       Impact factor: 3.984

4.  Long noncoding RNA PICSAR/miR-588/EIF6 axis regulates tumorigenesis of hepatocellular carcinoma by activating PI3K/AKT/mTOR signaling pathway.

Authors:  Zhikui Liu; Huanye Mo; Liankang Sun; Liang Wang; Tianxiang Chen; Bowen Yao; Runkun Liu; Yongshen Niu; Kangsheng Tu; Qiuran Xu; Nan Yang
Journal:  Cancer Sci       Date:  2020-09-23       Impact factor: 6.716
  4 in total

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