Literature DB >> 27448329

Treatment for Multiple Acute Cardiopulmonary Conditions in Older Adults Hospitalized with Pneumonia, Chronic Obstructive Pulmonary Disease, or Heart Failure.

Kumar Dharmarajan1,2, Kelly M Strait2, Mary E Tinetti3,4, Tara Lagu5,6,7, Peter K Lindenauer5,6,7, Joanne Lynn8, Michelle R Krukas9, Frank R Ernst9, Shu-Xia Li2, Harlan M Krumholz1,2,10,11.   

Abstract

OBJECTIVES: To determine how often hospitalized older adults principally diagnosed with pneumonia, chronic obstructive pulmonary disease (COPD), or heart failure (HF) are concurrently treated for two or more of these acute cardiopulmonary conditions.
DESIGN: Retrospective cohort study.
SETTING: 368 U.S. hospitals in the Premier research database. PARTICIPANTS: Individuals aged 65 and older principally hospitalized with pneumonia, COPD, or HF in 2009 or 2010. MEASUREMENTS: Proportion of diagnosed episodes of pneumonia, COPD, or HF concurrently treated for two or more of these acute cardiopulmonary conditions during the first 2 hospital days.
RESULTS: Of 91,709 diagnosed pneumonia hospitalizations, 32% received treatment for two or more acute cardiopulmonary conditions (18% for HF, 18% for COPD, 4% for both). Of 41,052 diagnosed COPD hospitalizations, 19% received treatment for two or more acute cardiopulmonary conditions (all of which involved additional HF treatment). Of 118,061 diagnosed HF hospitalizations, 38% received treatment for two or more acute cardiopulmonary conditions (34% for pneumonia, 9% for COPD, 5% for both).
CONCLUSION: Hospitalized older adults diagnosed with pneumonia, COPD, or HF are frequently treated for two or more acute cardiopulmonary conditions, suggesting that clinical syndromes often fall between traditional diagnostic categories. Research is needed to evaluate the risks and benefits of real-world treatment for the many older adults whose presentations elicit diagnostic uncertainty or concern about coexisting acute conditions.
© 2016, Copyright the Authors Journal compilation © 2016, The American Geriatrics Society.

Entities:  

Keywords:  cardiovascular disease; comorbidity; hospital medicine; pharmacoepidemiology; pulmonary diseases

Mesh:

Substances:

Year:  2016        PMID: 27448329      PMCID: PMC4988873          DOI: 10.1111/jgs.14303

Source DB:  PubMed          Journal:  J Am Geriatr Soc        ISSN: 0002-8614            Impact factor:   5.562


  44 in total

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