| Literature DB >> 27437281 |
Mohammed Shafi Abdulsalam1, Hari Chandana Ghanta2, Prabu Pandurangan3, Maya Menon4, Sheba S K Jacob5.
Abstract
Hypereosinophilic syndrome (HES) is a myeloproliferative disorder characterised by marked peripheral eosinophilia and end organ damage attributable to eosinophilia without secondary cause. Early recognition and treatment are essential to prevent morbidity and mortality. Cytoreduction with Steroids, Hydroxyurea and Imatinib are the main stay of treatment. Molecular studies like Fip1-like-1 fused with platelet derived growth factor receptor alpha (FIP1L1-PDGFRα) etc., are recommended in view of therapeutic implication. In this paper we report a rare case of HES developing in a lady 6 months after surgical removal of lymphangioma of spleen, which in itself is rare.Entities:
Keywords: Adrenal insufficiency; Cytoreduction; Lymphangioma of spleen; Tissue eosinophilia
Year: 2016 PMID: 27437281 PMCID: PMC4948457 DOI: 10.7860/JCDR/2016/19057.7770
Source DB: PubMed Journal: J Clin Diagn Res ISSN: 0973-709X