| Literature DB >> 27395047 |
Peggy Gandia1,2, Cyril Jaudet3, Etienne Chatelut1,4, Didier Concordet5.
Abstract
Positron emission tomography-computed tomography is a medical imaging method measuring the activity of a radiotracer chosen to accumulate in cancer cells. A recent trend of medical imaging analysis is to account for the radiotracer's pharmacokinetic properties at a voxel (three-dimensional-pixel) level to separate the different tissues. These analyses are closely linked to population pharmacokinetic-pharmacodynamic modelling. Kineticists possess the cultural background to improve medical imaging analysis. This article stresses the common points with population pharmacokinetics and highlights the methodological locks that need to be lifted.Entities:
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Year: 2017 PMID: 27395047 DOI: 10.1007/s40262-016-0437-9
Source DB: PubMed Journal: Clin Pharmacokinet ISSN: 0312-5963 Impact factor: 6.447