Literature DB >> 27383373

Self-Sealing Porous Silicon-Calcium Silicate Core-Shell Nanoparticles for Targeted siRNA Delivery to the Injured Brain.

Jinyoung Kang1, Jinmyoung Joo2, Ester J Kwon3, Matthew Skalak3, Sazid Hussain4, Zhi-Gang She4, Erkki Ruoslahti4,5, Sangeeta N Bhatia3,6,7,8, Michael J Sailor9,10,11.   

Abstract

Calcium ions react with silicic acid released from dissolving porous silicon nanoparticles to create an insoluble calcium silicate shell. The calcium silicate shell traps and protects an siRNA payload, which can be delivered to neuronal tissues in vitro or in vivo. Gene delivery is enhanced by the action of targeting and cell-penetrating peptides attached to the calcium silicate shell.
© 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  gene knockdowns; injured brains; photoluminescence; rabies virus glycoprotein peptides; targeted nanoparticles

Mesh:

Substances:

Year:  2016        PMID: 27383373      PMCID: PMC6274592          DOI: 10.1002/adma.201600634

Source DB:  PubMed          Journal:  Adv Mater        ISSN: 0935-9648            Impact factor:   30.849


  35 in total

1.  Mesoporous silica nanoparticles as a delivery system for hydrophobic anticancer drugs.

Authors:  Jie Lu; Monty Liong; Jeffrey I Zink; Fuyuhiko Tamanoi
Journal:  Small       Date:  2007-08       Impact factor: 13.281

Review 2.  Tailoring nanocarriers for intracellular protein delivery.

Authors:  Zhen Gu; Anuradha Biswas; Muxun Zhao; Yi Tang
Journal:  Chem Soc Rev       Date:  2011-05-12       Impact factor: 54.564

3.  Gated Luminescence Imaging of Silicon Nanoparticles.

Authors:  Jinmyoung Joo; Xiangyou Liu; Venkata Ramana Kotamraju; Erkki Ruoslahti; Yoonkey Nam; Michael J Sailor
Journal:  ACS Nano       Date:  2015-06-09       Impact factor: 15.881

4.  Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes.

Authors:  Lydia Alvarez-Erviti; Yiqi Seow; Haifang Yin; Corinne Betts; Samira Lakhal; Matthew J A Wood
Journal:  Nat Biotechnol       Date:  2011-03-20       Impact factor: 54.908

5.  Biodegradable luminescent porous silicon nanoparticles for in vivo applications.

Authors:  Ji-Ho Park; Luo Gu; Geoffrey von Maltzahn; Erkki Ruoslahti; Sangeeta N Bhatia; Michael J Sailor
Journal:  Nat Mater       Date:  2009-02-22       Impact factor: 43.841

6.  Association of blood proteins with large unilamellar liposomes in vivo. Relation to circulation lifetimes.

Authors:  A Chonn; S C Semple; P R Cullis
Journal:  J Biol Chem       Date:  1992-09-15       Impact factor: 5.157

Review 7.  The role of solid nanoparticle technology in the parenteral delivery of poorly water-soluble drugs.

Authors:  J E Kipp
Journal:  Int J Pharm       Date:  2004-10-13       Impact factor: 5.875

8.  Rabies virus binding to an acetylcholine receptor alpha-subunit peptide.

Authors:  T L Lentz
Journal:  J Mol Recognit       Date:  1990-04       Impact factor: 2.137

9.  Does a targeting ligand influence nanoparticle tumor localization or uptake?

Authors:  Kathleen F Pirollo; Esther H Chang
Journal:  Trends Biotechnol       Date:  2008-08-21       Impact factor: 19.536

10.  Oxidation-Induced Trapping of Drugs in Porous Silicon Microparticles.

Authors:  Nicole L Fry; Gerry R Boss; Michael J Sailor
Journal:  Chem Mater       Date:  2014-03-20       Impact factor: 9.811

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  31 in total

1.  A Porous Au@Rh Bimetallic Core-Shell Nanostructure as an H2 O2 -Driven Oxygenerator to Alleviate Tumor Hypoxia for Simultaneous Bimodal Imaging and Enhanced Photodynamic Therapy.

Authors:  Jinping Wang; Jingyu Sun; Wei Hu; Yuhao Wang; Tsengming Chou; Beilu Zhang; Qiang Zhang; Lei Ren; Hongjun Wang
Journal:  Adv Mater       Date:  2020-04-24       Impact factor: 30.849

2.  Antibiotic-loaded nanoparticles targeted to the site of infection enhance antibacterial efficacy.

Authors:  Sazid Hussain; Jinmyoung Joo; Jinyoung Kang; Byungji Kim; Gary B Braun; Zhi-Gang She; Dokyoung Kim; Aman P Mann; Tarmo Mölder; Tambet Teesalu; Santina Carnazza; Salvatore Guglielmino; Michael J Sailor; Erkki Ruoslahti
Journal:  Nat Biomed Eng       Date:  2018-01-22       Impact factor: 25.671

Review 3.  Challenges of gene delivery to the central nervous system and the growing use of biomaterial vectors.

Authors:  Devan L Puhl; Anthony R D'Amato; Ryan J Gilbert
Journal:  Brain Res Bull       Date:  2019-06-05       Impact factor: 4.077

4.  Lipidoid-siRNA Nanoparticle-Mediated IL-1β Gene Silencing for Systemic Arthritis Therapy in a Mouse Model.

Authors:  Ping Song; Chuanxu Yang; Jesper Skovhus Thomsen; Frederik Dagnæs-Hansen; Maria Jakobsen; Annemarie Brüel; Bent Deleuran; Jørgen Kjems
Journal:  Mol Ther       Date:  2019-05-15       Impact factor: 11.454

Review 5.  Rekindling RNAi Therapy: Materials Design Requirements for In Vivo siRNA Delivery.

Authors:  Byungji Kim; Ji-Ho Park; Michael J Sailor
Journal:  Adv Mater       Date:  2019-09-30       Impact factor: 30.849

6.  Self-Reporting Photoluminescent Porous Silicon Microparticles for Drug Delivery.

Authors:  Joanna Wang; Tushar Kumeria; Maria Teresa Bezem; Jian Wang; Michael J Sailor
Journal:  ACS Appl Mater Interfaces       Date:  2018-01-16       Impact factor: 9.229

7.  Oriented Nanofibrous Polymer Scaffolds Containing Protein-Loaded Porous Silicon Generated by Spray Nebulization.

Authors:  Jonathan M Zuidema; Tushar Kumeria; Dokyoung Kim; Jinyoung Kang; Joanna Wang; Geoffrey Hollett; Xuan Zhang; David S Roberts; Nicole Chan; Cari Dowling; Elena Blanco-Suarez; Nicola J Allen; Mark H Tuszynski; Michael J Sailor
Journal:  Adv Mater       Date:  2018-01-24       Impact factor: 30.849

8.  Enhanced Performance of a Molecular Photoacoustic Imaging Agent by Encapsulation in Mesoporous Silicon Nanoparticles.

Authors:  Jinyoung Kang; Dokyoung Kim; Junxin Wang; Yunho Han; Jonathan M Zuidema; Ali Hariri; Ji-Ho Park; Jesse V Jokerst; Michael J Sailor
Journal:  Adv Mater       Date:  2018-05-21       Impact factor: 30.849

9.  Porous Silicon Nanoparticles Embedded in Poly(lactic-co-glycolic acid) Nanofiber Scaffolds Deliver Neurotrophic Payloads to Enhance Neuronal Growth.

Authors:  Jonathan M Zuidema; Courtney M Dumont; Joanna Wang; Wyndham M Batchelor; Yi-Sheng Lu; Jinyoung Kang; Alessandro Bertucci; Noel M Ziebarth; Lonnie D Shea; Michael J Sailor
Journal:  Adv Funct Mater       Date:  2020-05-11       Impact factor: 18.808

10.  Quantum Ensembles of Silicon Nanoparticles: Discrimination of Static and Dynamic Photoluminescence Quenching Processes.

Authors:  Geoffrey Hollett; David S Roberts; Mollie Sewell; Emma Wensley; Julia Wagner; William Murray; Alex Krotz; Bryan Toth; Vibha Vijayakumar; Michael J Sailor
Journal:  J Phys Chem C Nanomater Interfaces       Date:  2019-07-01       Impact factor: 4.126

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