Literature DB >> 27370116

Quantitative analysis of treatment process time and throughput capacity for spot scanning proton therapy.

Kazumichi Suzuki1, Matthew B Palmer2, Narayan Sahoo1, Xiaodong Zhang1, Falk Poenisch1, Dennis S Mackin1, Amy Y Liu1, Richard Wu1, X Ronald Zhu1, Steven J Frank3, Michael T Gillin1, Andrew K Lee4.   

Abstract

PURPOSE: To determine the patient throughput and the overall efficiency of the spot scanning system by analyzing treatment time, equipment availability, and maximum daily capacity for the current spot scanning port at Proton Therapy Center Houston and to assess the daily throughput capacity for a hypothetical spot scanning proton therapy center.
METHODS: At their proton therapy center, the authors have been recording in an electronic medical record system all treatment data, including disease site, number of fields, number of fractions, delivered dose, energy, range, number of spots, and number of layers for every treatment field. The authors analyzed delivery system downtimes that had been recorded for every equipment failure and associated incidents. These data were used to evaluate the patient census, patient distribution as a function of the number of fields and total target volume, and equipment clinical availability. The duration of each treatment session from patient walk-in to patient walk-out of the spot scanning treatment room was measured for 64 patients with head and neck, central nervous system, thoracic, and genitourinary cancers. The authors retrieved data for total target volume and the numbers of layers and spots for all fields from treatment plans for a total of 271 patients (including the above 64 patients). A sensitivity analysis of daily throughput capacity was performed by varying seven parameters in a throughput capacity model.
RESULTS: The mean monthly equipment clinical availability for the spot scanning port in April 2012-March 2015 was 98.5%. Approximately 1500 patients had received spot scanning proton therapy as of March 2015. The major disease sites treated in September 2012-August 2014 were the genitourinary system (34%), head and neck (30%), central nervous system (21%), and thorax (14%), with other sites accounting for the remaining 1%. Spot scanning beam delivery time increased with total target volume and accounted for approximately 30%-40% of total treatment time for the total target volumes exceeding 200 cm(3), which was the case for more than 80% of the patients in this study. When total treatment time was modeled as a function of the number of fields and total target volume, the model overestimated total treatment time by 12% on average, with a standard deviation of 32%. A sensitivity analysis of throughput capacity for a hypothetical four-room spot scanning proton therapy center identified several priority items for improvements in throughput capacity, including operation time, beam delivery time, and patient immobilization and setup time.
CONCLUSIONS: The spot scanning port at our proton therapy center has operated at a high performance level and has been used to treat a large number of complex cases. Further improvements in efficiency may be feasible in the areas of facility operation, beam delivery, patient immobilization and setup, and optimization of treatment scheduling.

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Year:  2016        PMID: 27370116     DOI: 10.1118/1.4952731

Source DB:  PubMed          Journal:  Med Phys        ISSN: 0094-2405            Impact factor:   4.071


  9 in total

1.  Conventionally fractionated large volume head and neck re-irradiation using multileaf collimator-based robotic technique: A feasibility study.

Authors:  Houda Bahig; Catherine Wang; Sweet Ping Ng; Jack Phan
Journal:  Clin Transl Radiat Oncol       Date:  2020-07-02

2.  Multiple energy extraction reduces beam delivery time for a synchrotron-based proton spot-scanning system.

Authors:  James E Younkin; Martin Bues; Terence T Sio; Wei Liu; Xiaoning Ding; Sameer R Keole; Joshua B Stoker; Jiajian Shen
Journal:  Adv Radiat Oncol       Date:  2018-02-23

3.  Operational Performance of a Compact Proton Therapy System: A 5-Year Experience.

Authors:  Omar A Zeidan; Ethan Pepmiller; Twyla Willoughby; Zhiqiu Li; James Burkavage; Brian Harper; Michael Fraser; Katie Moffatt; Sanford L Meeks; Naren Ramakrishna
Journal:  Int J Part Ther       Date:  2022-07-01

4.  Retrospective analysis of reduced energy switching and room switching times on throughput efficiency of a multi-room proton therapy center.

Authors:  Dennis Mah; Chin Cheng Chen; A Omer Nawaz; Greg Galbreath; Reuven Shmulenson; Nancy Lee; Brian Chon
Journal:  Br J Radiol       Date:  2019-12-02       Impact factor: 3.039

Review 5.  Roadmap: proton therapy physics and biology.

Authors:  Harald Paganetti; Chris Beltran; Stefan Both; Lei Dong; Jacob Flanz; Keith Furutani; Clemens Grassberger; David R Grosshans; Antje-Christin Knopf; Johannes A Langendijk; Hakan Nystrom; Katia Parodi; Bas W Raaymakers; Christian Richter; Gabriel O Sawakuchi; Marco Schippers; Simona F Shaitelman; B K Kevin Teo; Jan Unkelbach; Patrick Wohlfahrt; Tony Lomax
Journal:  Phys Med Biol       Date:  2021-02-26       Impact factor: 4.174

6.  Analysis of treatment process time for real-time-image gated-spot-scanning proton-beam therapy (RGPT) system.

Authors:  Takaaki Yoshimura; Shinichi Shimizu; Takayuki Hashimoto; Kentaro Nishioka; Norio Katoh; Tetsuya Inoue; Hiroshi Taguchi; Koichi Yasuda; Taeko Matsuura; Seishin Takao; Masaya Tamura; Yoichi M Ito; Yuto Matsuo; Hiroshi Tamura; Kenji Horita; Kikuo Umegaki; Hiroki Shirato
Journal:  J Appl Clin Med Phys       Date:  2019-12-30       Impact factor: 2.102

7.  Quantitative analysis of treatments using real-time image gated spot-scanning with synchrotron-based proton beam therapy system log data.

Authors:  Takaaki Yoshimura; Shinichi Shimizu; Takayuki Hashimoto; Kentaro Nishioka; Norio Katoh; Hiroshi Taguchi; Koichi Yasuda; Taeko Matsuura; Seishin Takao; Masaya Tamura; Sodai Tanaka; Yoichi M Ito; Yuto Matsuo; Hiroshi Tamura; Kenji Horita; Kikuo Umegaki; Hiroki Shirato
Journal:  J Appl Clin Med Phys       Date:  2020-11-05       Impact factor: 2.102

Review 8.  Future Developments in Charged Particle Therapy: Improving Beam Delivery for Efficiency and Efficacy.

Authors:  Jacinta Yap; Andrea De Franco; Suzie Sheehy
Journal:  Front Oncol       Date:  2021-12-09       Impact factor: 5.738

9.  Quantitative analysis of MRI-guided radiotherapy treatment process time for tumor real-time gating efficiency.

Authors:  Lorenzo Placidi; Davide Cusumano; Luca Boldrini; Claudio Votta; Veronica Pollutri; Marco Valerio Antonelli; Giuditta Chiloiro; Angela Romano; Viola De Luca; Francesco Catucci; Luca Indovina; Vincenzo Valentini
Journal:  J Appl Clin Med Phys       Date:  2020-10-22       Impact factor: 2.243

  9 in total

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