Literature DB >> 27340364

A Glucose Sensing Contact Lens: A Non-Invasive Technique for Continuous Physiological Glucose Monitoring.

Ramachandram Badugu1, Joseph R Lakowicz1, Chris D Geddes2.   

Abstract

We have developed a range of glucose sensing contact lenses, using a daily, disposable contact lens embedded with newly developed boronic acid containing fluorophores. Our findings show that our approach may be suitable for the continuous monitoring of tear glucose levels in the range 50-1000 μM, which typically track blood glucose levels, which are ≈5-10 fold higher. Our non-invasive approach may well offer an alternative solution to current invasive glucose monitoring techniques for diabetes, such as "finger pricking."

Entities:  

Keywords:  Glucose monitoring; contact lens; continuous monitoring; non-invasive

Year:  2003        PMID: 27340364      PMCID: PMC4915737          DOI: 10.1023/A:1026103804104

Source DB:  PubMed          Journal:  J Fluoresc        ISSN: 1053-0509            Impact factor:   2.217


  17 in total

1.  Noninvasive glucose monitoring in diabetic patients: a preliminary evaluation.

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Journal:  Clin Chem       Date:  1992-09       Impact factor: 8.327

2.  Evaluation of a new system for self blood glucose monitoring.

Authors:  W L Clarke; D J Becker; D Cox; J V Santiago; N H White; J Betschart; K Eckenrode; L A Levandoski; E A Prusinski; L M Simineiro
Journal:  Diabetes Res Clin Pract       Date:  1988-02-19       Impact factor: 5.602

3.  An evaluation and comparison of Reflolux II and Glucometer II, two new portable reflectance meters for capillary blood glucose determination.

Authors:  G M Schier; R G Moses; I E Gan; S C Blair
Journal:  Diabetes Res Clin Pract       Date:  1988-02-19       Impact factor: 5.602

4.  Fluorescence-sensing methods.

Authors:  Zygmunt Gryczynski; Ignacy Gryczynski; Joseph R Lakowicz
Journal:  Methods Enzymol       Date:  2003       Impact factor: 1.600

5.  New color chemosensors for monosaccharides based on azo dyes.

Authors:  N DiCesare; J R Lakowicz
Journal:  Org Lett       Date:  2001-11-29       Impact factor: 6.005

6.  Noninvasive blood glucose sensors based on near-infrared spectroscopy.

Authors:  H M Heise; R Marbach; T Koschinsky; F A Gries
Journal:  Artif Organs       Date:  1994-06       Impact factor: 3.094

Review 7.  Clinical biochemistry of tears.

Authors:  N J Van Haeringen
Journal:  Surv Ophthalmol       Date:  1981 Sep-Oct       Impact factor: 6.048

8.  Noninvasive glucose monitoring of the aqueous humor of the eye: Part I. Measurement of very small optical rotations.

Authors:  B Rabinovitch; W F March; R L Adams
Journal:  Diabetes Care       Date:  1982 May-Jun       Impact factor: 19.112

9.  Ocular glucose sensor.

Authors:  W F March; B Rabinovitch; R Adams; J R Wise; M Melton
Journal:  Trans Am Soc Artif Intern Organs       Date:  1982

10.  A thermophilic apoglucose dehydrogenase as nonconsuming glucose sensor.

Authors:  S D'Auria; N Di Cesare; Z Gryczynski; I Gryczynski; M Rossi; J R Lakowicz
Journal:  Biochem Biophys Res Commun       Date:  2000-08-11       Impact factor: 3.575

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  19 in total

1.  Nanogold-plasmon-resonance-based glucose sensing.

Authors:  Kadir Aslan; Joseph R Lakowicz; Chris D Geddes
Journal:  Anal Biochem       Date:  2004-07-01       Impact factor: 3.365

2.  Conformational stability and domain coupling in D-glucose/D-galactose-binding protein from Escherichia coli.

Authors:  Grzegorz Piszczek; Sabato D'Auria; Maria Staiano; Mosè Rossi; Ann Ginsburg
Journal:  Biochem J       Date:  2004-07-01       Impact factor: 3.857

Review 3.  Progress in boronic acid-based fluorescent glucose sensors.

Authors:  Hao Fang; Gurpreet Kaur; Binghe Wang
Journal:  J Fluoresc       Date:  2004-09       Impact factor: 2.217

Review 4.  Ophthalmic glucose monitoring using disposable contact lenses--a review.

Authors:  Ramachandram Badugu; Joseph R Lakowicz; Chris D Geddes
Journal:  J Fluoresc       Date:  2004-09       Impact factor: 2.217

Review 5.  Fluorescence glucose detection: advances toward the ideal in vivo biosensor.

Authors:  Elizabeth A Moschou; Bethel V Sharma; Sapna K Deo; Sylvia Daunert
Journal:  J Fluoresc       Date:  2004-09       Impact factor: 2.217

Review 6.  Current problems and potential techniques in in vivo glucose monitoring.

Authors:  Y Wickramasinghe; Y Yang; S A Spencer
Journal:  J Fluoresc       Date:  2004-09       Impact factor: 2.217

7.  Evaluation of pyranine derivatives in boronic acid based saccharide sensing: significance of charge interaction between dye and quencher in solution and hydrogel.

Authors:  Frank E Cappuccio; Jeff T Suri; David B Cordes; Ritchie A Wessling; Bakthan Singaram
Journal:  J Fluoresc       Date:  2004-09       Impact factor: 2.217

8.  Enhanced fluorescence cyanide detection at physiologically lethal levels: reduced ICT-based signal transduction.

Authors:  Ramachandram Badugu; Joseph R Lakowicz; Chris D Geddes
Journal:  J Am Chem Soc       Date:  2005-03-16       Impact factor: 15.419

9.  Nanogold plasmon resonance-based glucose sensing. 2. Wavelength-ratiometric resonance light scattering.

Authors:  Kadir Aslan; Joseph R Lakowicz; Chris D Geddes
Journal:  Anal Chem       Date:  2005-04-01       Impact factor: 6.986

10.  OPHTHALMIC GLUCOSE MONITORING USING DISPOSABLE CONTACT LENSES.

Authors:  Ramachandram Badugu; Joseph R Lakowicz; Chris D Geddes
Journal:  Rev Fluoresc       Date:  2005
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