| Literature DB >> 27338221 |
Georg Osterhoff1, Elise F Morgan2, Sandra J Shefelbine3, Lamya Karim4, Laoise M McNamara5, Peter Augat6.
Abstract
This review will define the role of collagen and within-bone heterogeneity and elaborate the importance of trabecular and cortical architecture with regard to their effect on the mechanical strength of bone. For each of these factors, the changes seen with osteoporosis and ageing will be described and how they can compromise strength and eventually lead to bone fragility.Entities:
Keywords: Biomechanics; Bone fragility; Bone loss; Bone resorption; Collagen
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Year: 2016 PMID: 27338221 PMCID: PMC4955555 DOI: 10.1016/S0020-1383(16)47003-8
Source DB: PubMed Journal: Injury ISSN: 0020-1383 Impact factor: 2.586