Literature DB >> 27270304

Chemical and biological studies of reveromycin A.

Hiroyuki Osada1.   

Abstract

The research on antibiotics requires the integration of broad areas, such as microbiology, organic chemistry, biochemistry and pharmacology. It is similar to the field of chemical biology that is recently popular as an approach for drug discovery. When we isolate a new compound from a microorganism, we can pursue the interesting research on chemistry and biology. In this review, I would like to introduce our achievements in relation to reveromycin A.

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Year:  2016        PMID： 27270304     DOI： 10.1038/ja.2016.57

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN： 0021-8820            Impact factor:   2.649


  35 in total

1.  Chemical modification of reveromycin A and its biological activities.

Authors:  Takeshi Shimizu; Takeo Usui; Kiyotaka Machida; Kouichi Furuya; Hiroyuki Osada; Tadashi Nakata
Journal:  Bioorg Med Chem Lett       Date:  2002-12-02       Impact factor: 2.823

Review 2.  Introduction of new tools for chemical biology research on microbial metabolites.

Authors:  Hiroyuki Osada
Journal:  Biosci Biotechnol Biochem       Date:  2010-06-07       Impact factor: 2.043

Review 3.  Target identification of small molecules based on chemical biology approaches.

Authors:  Yushi Futamura; Makoto Muroi; Hiroyuki Osada
Journal:  Mol Biosyst       Date:  2013-05

4.  Structure-function analyses of cytochrome P450revI involved in reveromycin A biosynthesis and evaluation of the biological activity of its substrate, reveromycin T.

Authors:  Shunji Takahashi; Shingo Nagano; Toshihiko Nogawa; Naoki Kanoh; Masakazu Uramoto; Makoto Kawatani; Takeshi Shimizu; Takeshi Miyazawa; Yoshitsugu Shiro; Hiroyuki Osada
Journal:  J Biol Chem       Date:  2014-09-25       Impact factor: 5.157

Review 5.  Mechanisms of cancer metastasis to the bone.

Authors:  Juan Juan Yin; Claire B Pollock; Kathleen Kelly
Journal:  Cell Res       Date:  2005-01       Impact factor: 25.617

6.  The multidrug resistance-associated protein (MRP) subfamily (Yrs1/Yor1) of Saccharomyces cerevisiae is important for the tolerance to a broad range of organic anions.

Authors:  Z Cui; D Hirata; E Tsuchiya; H Osada; T Miyakawa
Journal:  J Biol Chem       Date:  1996-06-21       Impact factor: 5.157

7.  Inhibitory action of reveromycin A on TGF-alpha-dependent growth of ovarian carcinoma BG-1 in vitro and in vivo.

Authors:  H Takahashi; Y Yamashita; H Takaoka; J Nakamura; M Yoshihama; H Osada
Journal:  Oncol Res       Date:  1997       Impact factor: 5.574

8.  Characterization of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus unveiling new insights into dialkylmaleic anhydride and polyketide biosynthesis.

Authors:  Wenli Li; Jianhua Ju; Scott R Rajski; Hiroyuki Osada; Ben Shen
Journal:  J Biol Chem       Date:  2008-08-15       Impact factor: 5.157

9.  Analysis of the biosynthetic gene cluster for the polyether antibiotic monensin in Streptomyces cinnamonensis and evidence for the role of monB and monC genes in oxidative cyclization.

Authors:  Markiyan Oliynyk; Christian B W Stark; Apoorva Bhatt; Michelle A Jones; Zoë A Hughes-Thomas; Christopher Wilkinson; Zoryana Oliynyk; Yuliya Demydchuk; James Staunton; Peter F Leadlay
Journal:  Mol Microbiol       Date:  2003-09       Impact factor: 3.501

10.  Inhibition of Hsp90 activates osteoclast c-Src signaling and promotes growth of prostate carcinoma cells in bone.

Authors:  Akihiro Yano; Shinji Tsutsumi; Shiro Soga; Min-Jung Lee; Jane Trepel; Hiroyuki Osada; Len Neckers
Journal:  Proc Natl Acad Sci U S A       Date:  2008-10-07       Impact factor: 11.205
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  3 in total

1.  Reveromycins A and B from Streptomyces sp. 3-10: Antifungal Activity against Plant Pathogenic Fungi In vitro and in a Strawberry Food Model System.

Authors:  Ang Lyu; Hao Liu; Hongjie Che; Long Yang; Jing Zhang; Mingde Wu; Weidong Chen; Guoqing Li
Journal:  Front Microbiol       Date:  2017-04-03       Impact factor: 5.640

2.  Biocontrol of Aspergillus flavus on Peanut Kernels Using Streptomyces yanglinensis 3-10.

Authors:  Qaiser Shakeel; Ang Lyu; Jing Zhang; Mingde Wu; Guoqing Li; Tom Hsiang; Long Yang
Journal:  Front Microbiol       Date:  2018-05-23       Impact factor: 5.640

3.  The biosynthetic pathway to ossamycin, a macrocyclic polyketide bearing a spiroacetal moiety.

Authors:  Oksana Bilyk; Markiyan Samborskyy; Peter F Leadlay
Journal:  PLoS One       Date:  2019-04-30       Impact factor: 3.240
  3 in total

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