| Literature DB >> 27246759 |
Eva-Maria Willing1, Vimal Rawat1, Terezie Mandáková2, Florian Maumus3, Geo Velikkakam James1, Karl J V Nordström1, Claude Becker4, Norman Warthmann4,5, Claudia Chica6, Bogna Szarzynska6, Matthias Zytnicki3, Maria C Albani1, Christiane Kiefer1, Sara Bergonzi1, Loren Castaings1, Julieta L Mateos1, Markus C Berns1, Nora Bujdoso1, Thomas Piofczyk1, Laura de Lorenzo7, Cristina Barrero-Sicilia8, Isabel Mateos7, Mathieu Piednoël1, Jörg Hagmann4, Romy Chen-Min-Tao6, Raquel Iglesias-Fernández8, Stephan C Schuster9, Carlos Alonso-Blanco7, François Roudier6, Pilar Carbonero8, Javier Paz-Ares7, Seth J Davis1, Ales Pecinka1, Hadi Quesneville3, Vincent Colot6, Martin A Lysak2, Detlef Weigel4, George Coupland1, Korbinian Schneeberger1.
Abstract
Despite evolutionary conserved mechanisms to silence transposable element activity, there are drastic differences in the abundance of transposable elements even among closely related plant species. We conducted a de novo assembly for the 375 Mb genome of the perennial model plant, Arabis alpina. Analysing this genome revealed long-lasting and recent transposable element activity predominately driven by Gypsy long terminal repeat retrotransposons, which extended the low-recombining pericentromeres and transformed large formerly euchromatic regions into repeat-rich pericentromeric regions. This reduced capacity for long terminal repeat retrotransposon silencing and removal in A. alpina co-occurs with unexpectedly low levels of DNA methylation. Most remarkably, the striking reduction of symmetrical CG and CHG methylation suggests weakened DNA methylation maintenance in A. alpina compared with Arabidopsis thaliana. Phylogenetic analyses indicate a highly dynamic evolution of some components of methylation maintenance machinery that might be related to the unique methylation in A. alpina.Entities:
Year: 2015 PMID： 27246759 DOI： 10.1038/nplants.2014.23
Source DB: PubMed Journal: Nat Plants ISSN： 2055-0278 Impact factor: 15.793