Literature DB >> 27246221

Molecular, Cellular, and Physiological Characterization of Sirtuin 7 (SIRT7).

Jiyung Shin1, Danica Chen2.   

Abstract

Sirtuin 7 (SIRT7), a histone 3 lysine 18 (H3K18) deacetylase, functions at chromatin to suppress endoplasmic reticulum (ER) stress and mitochondrial protein folding stress (PFS(mt)), and prevent the development of fatty liver disease and hematopoietic stem cell aging. In this chapter, we provide a methodology to characterize the molecular, cellular, and physiological functions of SIRT7.

Entities:  

Keywords:  Aging; ER UPR (UPRer); ER stress; Fatty liver; Hematopoietic stem cell; Mitochondrial UPR (UPRmt); Mitochondrial protein folding stress; Myc; NRF1; SIRT7

Mesh：

Substances：

Year:  2016        PMID： 27246221      PMCID： PMC7233270          DOI： 10.1007/978-1-4939-3667-0_18

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN： 1064-3745


  15 in total

1.  Genomic instability and aging-like phenotype in the absence of mammalian SIRT6.

Authors:  Raul Mostoslavsky; Katrin F Chua; David B Lombard; Wendy W Pang; Miriam R Fischer; Lionel Gellon; Pingfang Liu; Gustavo Mostoslavsky; Sonia Franco; Michael M Murphy; Kevin D Mills; Parin Patel; Joyce T Hsu; Andrew L Hong; Ethan Ford; Hwei-Ling Cheng; Caitlin Kennedy; Nomeli Nunez; Roderick Bronson; David Frendewey; Wojtek Auerbach; David Valenzuela; Margaret Karow; Michael O Hottiger; Stephen Hursting; J Carl Barrett; Leonard Guarente; Richard Mulligan; Bruce Demple; George D Yancopoulos; Frederick W Alt
Journal:  Cell       Date:  2006-01-27       Impact factor: 41.582

2.  Increase in activity during calorie restriction requires Sirt1.

Authors:  Danica Chen; Andrew D Steele; Susan Lindquist; Leonard Guarente
Journal:  Science       Date:  2005-12-09       Impact factor: 47.728

Review 3.  Ten years of NAD-dependent SIR2 family deacetylases: implications for metabolic diseases.

Authors:  Shin-ichiro Imai; Leonard Guarente
Journal:  Trends Pharmacol Sci       Date:  2010-03-11       Impact factor: 14.819

4.  Stem cell aging. A mitochondrial UPR-mediated metabolic checkpoint regulates hematopoietic stem cell aging.

Authors:  Mary Mohrin; Jiyung Shin; Yufei Liu; Katharine Brown; Hanzhi Luo; Yannan Xi; Cole M Haynes; Danica Chen
Journal:  Science       Date:  2015-03-20       Impact factor: 47.728

5.  SIRT7 represses Myc activity to suppress ER stress and prevent fatty liver disease.

Authors:  Jiyung Shin; Ming He; Yufei Liu; Silvana Paredes; Lidia Villanova; Katharine Brown; Xiaolei Qiu; Noushin Nabavi; Mary Mohrin; Kathleen Wojnoonski; Patrick Li; Hwei-Ling Cheng; Andrew J Murphy; David M Valenzuela; Hanzhi Luo; Pankaj Kapahi; Ronald Krauss; Raul Mostoslavsky; George D Yancopoulos; Frederick W Alt; Katrin F Chua; Danica Chen
Journal:  Cell Rep       Date:  2013-11-07       Impact factor: 9.423

6.  SIRT4 protein suppresses tumor formation in genetic models of Myc-induced B cell lymphoma.

Authors:  Seung Min Jeong; Annie Lee; Jaewon Lee; Marcia C Haigis
Journal:  J Biol Chem       Date:  2013-12-24       Impact factor: 5.157

7.  SIRT3 reverses aging-associated degeneration.

Authors:  Katharine Brown; Stephanie Xie; Xiaolei Qiu; Mary Mohrin; Jiyung Shin; Yufei Liu; Dan Zhang; David T Scadden; Danica Chen
Journal:  Cell Rep       Date:  2013-01-31       Impact factor: 9.423

Review 8.  Recent progress in the biology and physiology of sirtuins.

Authors:  Toren Finkel; Chu-Xia Deng; Raul Mostoslavsky
Journal:  Nature       Date:  2009-07-30       Impact factor: 49.962

9.  SIRT7 links H3K18 deacetylation to maintenance of oncogenic transformation.

Authors:  Matthew F Barber; Eriko Michishita-Kioi; Yuanxin Xi; Luisa Tasselli; Mitomu Kioi; Zarmik Moqtaderi; Ruth I Tennen; Silvana Paredes; Nicolas L Young; Kaifu Chen; Kevin Struhl; Benjamin A Garcia; Or Gozani; Wei Li; Katrin F Chua
Journal:  Nature       Date:  2012-07-05       Impact factor: 49.962

10.  SIRT2 deficiency modulates macrophage polarization and susceptibility to experimental colitis.

Authors:  Giuseppe Lo Sasso; Keir Joe Menzies; Adrienne Mottis; Alessandra Piersigilli; Alessia Perino; Hiroyasu Yamamoto; Kristina Schoonjans; Johan Auwerx
Journal:  PLoS One       Date:  2014-07-29       Impact factor: 3.240
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  1 in total

1.  Genetic variations in the sheep SIRT7 gene and their correlation with body size traits.

Authors:  Hongwei Xu; Xiaoyu Zhang; Rongxin Zang; Yong Cai; Xin Cao; Jutian Yang; Jie Li; Xianyong Lan; Jianping Wu
Journal:  Arch Anim Breed       Date:  2019-04-16
  1 in total

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