Literature DB >> 16339438

Increase in activity during calorie restriction requires Sirt1.

Danica Chen1, Andrew D Steele, Susan Lindquist, Leonard Guarente.   

Abstract

Sir2 (silent information regulator 2) is a nicotinamide adenine dinucleotide-dependent deacetylase required for longevity due to calorie restriction in yeast and Drosophila. In mammals, calorie restriction induces a complex pattern of physiological and behavioral changes. Here we report that the mammalian Sir2 ortholog, Sirt1, is required for the induction of a phenotype by calorie restriction in mice.

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Year:  2005        PMID： 16339438     DOI： 10.1126/science.1118357

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  192 in total

Review 1.  Regulation of SIRT1 in cellular functions: role of polyphenols.

Authors:  Sangwoon Chung; Hongwei Yao; Samuel Caito; Jae-Woong Hwang; Gnanapragasam Arunachalam; Irfan Rahman
Journal:  Arch Biochem Biophys       Date:  2010-05-05       Impact factor: 4.013

2.  SIRT1 activates MAO-A in the brain to mediate anxiety and exploratory drive.

Authors:  Sergiy Libert; Kelli Pointer; Eric L Bell; Abhirup Das; Dena E Cohen; John M Asara; Karen Kapur; Sven Bergmann; Martin Preisig; Takeshi Otowa; Kenneth S Kendler; Xiangning Chen; John M Hettema; Edwin J van den Oord; Justin P Rubio; Leonard Guarente
Journal:  Cell       Date:  2011-12-08       Impact factor: 41.582

Review 3.  Protective effects and mechanisms of sirtuins in the nervous system.

Authors:  Feng Zhang; Suping Wang; Li Gan; Peter S Vosler; Yanqin Gao; Michael J Zigmond; Jun Chen
Journal:  Prog Neurobiol       Date:  2011-09-10       Impact factor: 11.685

4.  Sirt1 improves healthy ageing and protects from metabolic syndrome-associated cancer.

Authors:  Daniel Herranz; Maribel Muñoz-Martin; Marta Cañamero; Francisca Mulero; Barbara Martinez-Pastor; Oscar Fernandez-Capetillo; Manuel Serrano
Journal:  Nat Commun       Date:  2010-04-12       Impact factor: 14.919

Review 5.  Sirtuins mediate mammalian metabolic responses to nutrient availability.

Authors:  Angeliki Chalkiadaki; Leonard Guarente
Journal:  Nat Rev Endocrinol       Date:  2012-01-17       Impact factor: 43.330

6.  Leptin boosts cellular metabolism by activating AMPK and the sirtuins to reduce tau phosphorylation and β-amyloid in neurons.

Authors:  Steven J Greco; Ashkan Hamzelou; Jane M Johnston; Mark A Smith; J Wesson Ashford; Nikolaos Tezapsidis
Journal:  Biochem Biophys Res Commun       Date:  2011-09-17       Impact factor: 3.575

7.  Changes in behaviors of male C57BL/6J mice across adult life span and effects of dietary restriction.

Authors:  Andreas Fahlström; Hugo Zeberg; Brun Ulfhake
Journal:  Age (Dordr)       Date:  2011-10-12

Review 8.  An epigenetic perspective on the free radical theory of development.

Authors:  Michael J Hitchler; Frederick E Domann
Journal:  Free Radic Biol Med       Date:  2007-07-10       Impact factor: 7.376

Review 9.  A scale-free systems theory of motivation and addiction.

Authors:  R Andrew Chambers; Warren K Bickel; Marc N Potenza
Journal:  Neurosci Biobehav Rev       Date:  2007-05-03       Impact factor: 8.989

10.  Endospanin-2 enhances skeletal muscle energy metabolism and running endurance capacity.

Authors:  Steve Lancel; Matthijs Kc Hesselink; Estelle Woldt; Yves Rouillé; Emilie Dorchies; Stephane Delhaye; Christian Duhem; Quentin Thorel; Alicia Mayeuf-Louchart; Benoit Pourcet; Valérie Montel; Gert Schaart; Nicolas Beton; Florence Picquet; Olivier Briand; Jean Pierre Salles; Hélène Duez; Patrick Schrauwen; Bruno Bastide; Bernard Bailleul; Bart Staels; Yasmine Sebti
Journal:  JCI Insight       Date:  2018-05-03
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