BACKGROUND: For Parkinson's disease (PD), essential tremor (ET), and dystonia patients with deep brain stimulation (DBS) implants, magnetic resonance imaging (MRI) requires additional safety considerations due to potentially hazardous interactions. OBJECTIVE: A propensity-matched cohort of DBS-implanted patients was analyzed to determine the likelihood of needing MRI. METHODS: Patients with new DBS full-system implants (n = 576) were identified in the Truven Health MarketScan® Commercial Claims and Medicare Supplemental Databases (2009-2012). Patients diagnosed with PD, ET, or dystonia and no DBS implant were identified (DBS-indicated patients: n = 11,216). The DBS-indicated patients were continuously enrolled for 4 years and matched for age, gender, and propensity score based on comorbid conditions to DBS-implanted patients (n = 4,878 and 543, respectively). A Kaplan-Meier survival curve of time to first MRI was extrapolated to 10 years. RESULTS: An estimated 56-57% of DBS-indicated patients need an MRI within 5 years and 66-75% within 10 years after implantation. While 92% of DBS-implanted patients' MRI after implantation was of the head, for DBS-indicated patients, 62% of MRIs were of the body, potentially unrelated to the primary diagnosis. CONCLUSIONS: This analysis highlights the projected utilization of MRI in the DBS population for head and full-body images.
BACKGROUND: For Parkinson's disease (PD), essential tremor (ET), and dystoniapatients with deep brain stimulation (DBS) implants, magnetic resonance imaging (MRI) requires additional safety considerations due to potentially hazardous interactions. OBJECTIVE: A propensity-matched cohort of DBS-implanted patients was analyzed to determine the likelihood of needing MRI. METHODS:Patients with new DBS full-system implants (n = 576) were identified in the Truven Health MarketScan® Commercial Claims and Medicare Supplemental Databases (2009-2012). Patients diagnosed with PD, ET, or dystonia and no DBS implant were identified (DBS-indicated patients: n = 11,216). The DBS-indicated patients were continuously enrolled for 4 years and matched for age, gender, and propensity score based on comorbid conditions to DBS-implanted patients (n = 4,878 and 543, respectively). A Kaplan-Meier survival curve of time to first MRI was extrapolated to 10 years. RESULTS: An estimated 56-57% of DBS-indicated patients need an MRI within 5 years and 66-75% within 10 years after implantation. While 92% of DBS-implanted patients' MRI after implantation was of the head, for DBS-indicated patients, 62% of MRIs were of the body, potentially unrelated to the primary diagnosis. CONCLUSIONS: This analysis highlights the projected utilization of MRI in the DBS population for head and full-body images.
Authors: Alexandre Boutet; Clement T Chow; Keshav Narang; Gavin J B Elias; Clemens Neudorfer; Jürgen Germann; Manish Ranjan; Aaron Loh; Alastair J Martin; Walter Kucharczyk; Christopher J Steele; Ileana Hancu; Ali R Rezai; Andres M Lozano Journal: Radiology Date: 2020-06-23 Impact factor: 11.105
Authors: Yanan Sui; Ye Tian; Wai Kin Daniel Ko; Zhiyan Wang; Fumin Jia; Andreas Horn; Dirk De Ridder; Ki Sueng Choi; Ausaf A Bari; Shouyan Wang; Clement Hamani; Kenneth B Baker; Andre G Machado; Tipu Z Aziz; Erich Talamoni Fonoff; Andrea A Kühn; Hagai Bergman; Terence Sanger; Hesheng Liu; Suzanne N Haber; Luming Li Journal: Front Neurol Date: 2021-01-28 Impact factor: 4.003
Authors: M Arcan Erturk; Eric Panken; Mark J Conroy; Jonathan Edmonson; Jeff Kramer; Jacob Chatterton; S Riki Banerjee Journal: Front Hum Neurosci Date: 2020-02-20 Impact factor: 3.169