Literature DB >> 27231731

Pyristriatins A and B: Pyridino-Cyathane Antibiotics from the Basidiomycete Cyathus cf. striatus.

Christian Richter1, Soleiman E Helaly1,2, Benjarong Thongbai3, Kevin D Hyde3, Marc Stadler1.   

Abstract

Two novel pyridino-cyathane diterpenoids, pyristriatins A and B (1 and 2), together with striatin C (3) were isolated from cultures of Cyathus cf. striatus, a basidiomycete that was found during a field trip in northern Thailand. The pyristriatins showed antimicrobial effects against Gram-positive bacteria and fungi. The isolation, structure elucidation, relative configuration, and biological and cytotoxic activity are described. Their structures were assigned by HRMS and NMR spectroscopy. We also describe the first 2D NMR assignment of striatin C. Pyristriatins A and B are the first cyathane natural products featuring a pyridine ring.

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Year:  2016        PMID： 27231731     DOI： 10.1021/acs.jnatprod.6b00194

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  10 in total

1.  Genome Mining of Micromonospora yangpuensis DSM 45577 as a Producer of an Anthraquinone-Fused Enediyne.

Authors:  Xiaohui Yan; Jian-Jun Chen; Ajeeth Adhikari; Dong Yang; Ivana Crnovcic; Nan Wang; Chin-Yuan Chang; Christoph Rader; Ben Shen
Journal:  Org Lett       Date:  2017-10-31       Impact factor: 6.005

2.  Ijuhya vitellina sp. nov., a novel source for chaetoglobosin A, is a destructive parasite of the cereal cyst nematode Heterodera filipjevi.

Authors:  Samad Ashrafi; Soleiman Helaly; Hans-Josef Schroers; Marc Stadler; Katja R Richert-Poeggeler; Abdelfattah A Dababat; Wolfgang Maier
Journal:  PLoS One       Date:  2017-07-12       Impact factor: 3.240

Review 3.  Fungal Identification Using Molecular Tools: A Primer for the Natural Products Research Community.

Authors:  Huzefa A Raja; Andrew N Miller; Cedric J Pearce; Nicholas H Oberlies
Journal:  J Nat Prod       Date:  2017-02-15       Impact factor: 4.050

4.  New nematicidal and antimicrobial secondary metabolites from a new species in the new genus, Pseudobambusicola thailandica.

Authors:  Zeljka Rupcic; Clara Chepkirui; Margarita Hernández-Restrepo; Pedro W Crous; Janet Jennifer Luangsa-Ard; Marc Stadler
Journal:  MycoKeys       Date:  2018-03-22       Impact factor: 2.984

5.  Five Unprecedented Secondary Metabolites from the Spider Parasitic Fungus Akanthomyces novoguineensis.

Authors:  Soleiman E Helaly; Wilawan Kuephadungphan; Souwalak Phongpaichit; Janet Jennifer Luangsa-Ard; Vatcharin Rukachaisirikul; Marc Stadler
Journal:  Molecules       Date:  2017-06-14       Impact factor: 4.411

6.  Akanthopyrones A-D, α-Pyrones Bearing a 4-O-Methyl-β-d-glucopyranose Moiety from the Spider-Associated Ascomycete Akanthomyces novoguineensis.

Authors:  Wilawan Kuephadungphan; Soleiman E Helaly; Charuwan Daengrot; Souwalak Phongpaichit; Janet Jennifer Luangsa-Ard; Vatcharin Rukachaisirikul; Marc Stadler
Journal:  Molecules       Date:  2017-07-18       Impact factor: 4.411

Review 7.  A Decade of Antifungal Leads from Natural Products: 2010-2019.

Authors:  Mohammed Aldholmi; Pascal Marchand; Isabelle Ourliac-Garnier; Patrice Le Pape; A Ganesan
Journal:  Pharmaceuticals (Basel)       Date:  2019-12-12

8.  Antifungal activity of dendritic cell lysosomal proteins against Cryptococcus neoformans.

Authors:  Benjamin N Nelson; Savannah G Beakley; Sierra Posey; Brittney Conn; Emma Maritz; Janakiram Seshu; Karen L Wozniak
Journal:  Sci Rep       Date:  2021-06-30       Impact factor: 4.379

9.  Antiviral 4-Hydroxypleurogrisein and Antimicrobial Pleurotin Derivatives from Cultures of the Nematophagous Basidiomycete Hohenbuehelia grisea.

Authors:  Birthe Sandargo; Benjarong Thongbai; Dimas Praditya; Eike Steinmann; Marc Stadler; Frank Surup
Journal:  Molecules       Date:  2018-10-19       Impact factor: 4.411

10.  Furanones and Anthranilic Acid Derivatives from the Endophytic Fungus Dendrothyrium variisporum.

Authors:  Rémy B Teponno; Sara R Noumeur; Soleiman E Helaly; Stephan Hüttel; Daoud Harzallah; Marc Stadler
Journal:  Molecules       Date:  2017-10-09       Impact factor: 4.411
  10 in total

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